N,N-diethyl-N'-phenyl-propanediyldiamine | 52994-21-5

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N,N-diethyl-N'-phenyl-propanediyldiamine
• 英文别名: N,N-Diaethyl-N'-phenyl-propandiyldiamin；1-Anilino-3-diaethylamino-propan；N',N'-diethyl-N-phenyl-propane-1,3-diamine；N',N'-diethyl-N-phenylpropane-1,3-diamine
• CAS: 52994-21-5
• 化学式: C₁₃H₂₂N₂
• 分子量: 206.331
• InChiKey: WXFNPHZNUUIRFT-UHFFFAOYSA-N

物化性质

• 沸点：
  128-130 °C(Press: 1 Torr)
• 密度：
  0.958±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  15
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  15.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  N,N-diethyl-N'-phenyl-propanediyldiamine 、 氯甲酸乙酯 生成 (3-diethylamino-propyl)-phenyl-carbamic acid ethyl ester
  参考文献：
  名称：

  Larizza; Brancaccio, Gazzetta Chimica Italiana, 1959, vol. 89, p. 2402,2404

  摘要：

  DOI：
• 作为产物：
  描述：

  N-苯基甲酰胺 在 盐酸 、 sodium 、 苯 作用下， 生成 N,N-diethyl-N'-phenyl-propanediyldiamine
  参考文献：
  名称：

  Leffler; Matson, Journal of the American Chemical Society, 1948, vol. 70, p. 3439,3440,3441

  摘要：

  DOI：

文献信息

• [EN] DNA-PK INHIBITORS<br/>[FR] INHIBITEURS D'ADN-PK
  申请人：CANCER REC TECH LTD

  公开号：WO2003024949A1

  公开（公告）日：2003-03-27

  The invention relates to the use of compounds of formula (I) and isomers, salts, solvates, chemically protected forms, and prodrugs thereof, in the preparation of a medicament for inhibiting the activity of DNA-PK, wherein R?1 and R2¿ are independently hydrogen, an optionally substituted C¿1-7? alkyl group, C3-20 heterocyclyl group, or C5-20 aryl group, or may together form, along with the nitrogen atom to which they are attached, an optionally substituted heterocyclic ring having from 4 to 8 ring atoms; X and Y are selected from CR?4¿ and O, O and CR'4 and NR'4 and N, where the unsaturation is in the appropriate place in the ring, and where one of R?3 and R4 or R'4¿ is an optionally substituted C¿3-20? heteroaryl or C5-20 aryl group, and the other of R?3 and R4 or R'4¿ is H, or R?3 and R4 or R'4¿ together are -A-B-, which collectively represent a fused optionally substituted aromatic ring. The compounds also selectively inhibit the activity of DNA-PK compared to PI 3-kinase and/or ATM.

  本发明涉及使用式(I)化合物及其异构体、盐、溶剂合物、化学保护形式和前药，在制备用于抑制DNA-PK活性的药物中使用，其中R?1和R2¿分别为氢、可选取代的C¿1-7?烷基、C3-20杂环基或C5-20芳基，或者可以与它们连接的氮原子一起形成具有4到8个环原子的可选取代杂环环；X和Y从CR?4¿和O、O和CR'4和NR'4和N中选取，其中不饱和度在环中适当位置，其中R?3和R4或R'4¿中的一个为可选取代的C¿3-20?杂芳基或C5-20芳基，而另一个为H，或者R?3和R4或R'4¿一起是-A-B-，它们共同代表一个融合的可选取代芳香环。这些化合物还比PI 3-激酶和/或ATM选择性地抑制DNA-PK活性。
• Multiple catalyst system for olefin polymerization and polymers produced therefrom
  申请人：——

  公开号：US20040138392A1

  公开（公告）日：2004-07-15

  This invention relates to a polymer comprising one or more C3 to C40 olefins, optionally one or more diolefins, and less than 15 mole % of ethylene, where the polymer has: a) a Dot T-Peel of 1 Newton or more; and b) a branching index (g′) of 0.95 or less measured at the Mz of the polymer; c) an Mw of 100,000 or less. This invention also relates a polymer comprising one or more C3 to C40 olefins where the polymer has: a) a Dot T-Peel of 1 Newton or more on Kraft paper; b) a branching index (g′) of 0.95 or less measured at the Mz of the polymer; c) a Mw of 10,000 to 100,000; and d) a heat of fusion of 1 to 70 J/g. This invention also relates a polymer comprising one or more C3 to C40 olefins where the polymer has: a) a Dot T-Peel of 1 Newton or more on Kraft paper; b) a branching index (g′) of 0.98 or less measured at the Mz of the polymer; c) a Mw of 10,000 to 60,000; d) a heat of fusion of 1 to 50 J/g. This invention also relates to a homopolypropylene or a copolymer of propylene and up to 5 mole % ethylene having: a) an isotactic run length of 1 to 30 (isotactic run length “IRL” is defined to be the percent of mmmm pentad divided by 0.5×percent of mmmr pentad) as determined by Carbon 13 NMR, preferably 3 to 25, more preferably 4 to 20, b) a percent of r dyad of greater than 20%, preferably from 20 to 70% as determined by Carbon 13 NMR, and c) a heat of fusion of 70 J/g or less, preferably 60 J/g or less, more preferably between 1 and 55 J/g, more preferably between 4 and 50 J/g. This invention further relates to a process to produce an olefin polymer comprising: 1) selecting a first catalyst component capable of producing a polymer having an Mw of 100,000 or less and a crystallinity of 5% or less at selected polymerization conditions; 2) selecting a second catalyst component capable of producing polymer having an Mw of 100,000 or less and a crystallinity of 20% or more at the selected polymerization conditions; 3) contacting the catalyst components in the presence of one or more activators with one or more C3 to C40 olefins, at the selected polymerization conditions in a reaction zone; 4) obtaining the polymer. This invention further relates to a continuous process to produce a branched olefin polymer comprising: 1) selecting a first catalyst component capable of producing a polymer having an Mw of 100,000 or less and a crystallinity of 5% or less under selected polymerization conditions; 2) selecting a second catalyst component capable of producing polymer having an Mw of 100,000 or less and a crystallinity of 20% or more at the selected polymerization conditions; 3) contacting the catalyst components in the presence of one or more activators with one or more C3 to C40 olefins, and, optionally one or more diolefins; 4) at a temperature of greater than 100° C.; 5) at a residence time of 120 minutes or less; 6) wherein the ratio of the first catalyst to the second catalyst is from 1:1 to 50:1; 7) wherein the activity of the catalyst components is at least 100 kilograms of polymer per gram of the catalyst components; and wherein at least 20% of the olefins are converted to polymer.

  本发明涉及一种聚合物，包括一种或多种C3至C40的烯烃，可选地包括一种或多种二烯烃，以及少于15摩尔％的乙烯，其中该聚合物具有：a）1牛顿或更多的Dot T-Peel；和b）在聚合物的Mz处测量的分支指数（g'）为0.95或更低；c）Mw为100,000或以下。本发明还涉及一种聚合物，包括一种或多种C3至C40的烯烃，其中该聚合物具有：a）在Kraft纸上1牛顿或更多的Dot T-Peel；b）在聚合物的Mz处测量的分支指数（g'）为0.95或更低；c）Mw为10,000至100,000；以及d）熔融热为1至70 J/g。本发明还涉及一种聚合物，包括一种或多种C3至C40的烯烃，其中该聚合物具有：a）在Kraft纸上1牛顿或更多的Dot T-Peel；b）在聚合物的Mz处测量的分支指数（g'）为0.98或更低；c）Mw为10,000至60,000；d）熔融热为1至50 J/g。本发明还涉及一种均聚丙烯或丙烯和最多5摩尔％乙烯的共聚物，具有：a）由Carbon 13 NMR确定的1至30的异构跑长（异构跑长“IRL”定义为mmmm五元组的百分比除以mmmr五元组的0.5×百分比），优选为3至25，更优选为4至20；b）由Carbon 13 NMR确定的大于20％的r二元组的百分比，优选为20至70％；以及c）熔融热为70 J/g或更低，优选为60 J/g或更低，更优选为1至55 J/g，更优选为4至50 J/g。本发明还涉及一种生产烯烃聚合物的过程，包括：1）选择第一催化剂组分，能够在选择的聚合条件下产生具有100,000或更低的Mw和5％或更低的结晶度的聚合物；2）选择第二催化剂组分，能够在选择的聚合条件下产生具有100,000或更低的Mw和20％或更高的结晶度的聚合物；3）在存在一种或多种活化剂的情况下，将催化剂组分与一种或多种C3至C40烯烃，在选择的聚合条件下，在反应区域中接触；4）获得聚合物。本发明还涉及一种连续生产支化烯烃聚合物的过程，包括：1）选择第一催化剂组分，能够在选择的聚合条件下产生具有100,000或更低的Mw和5％或更低的结晶度的聚合物；2）选择第二催化剂组分，能够在选择的聚合条件下产生具有100,000或更低的Mw和20％或更高的结晶度的聚合物；3）在存在一种或多种活化剂的情况下，将催化剂组分与一种或多种C3至C40烯烃和可选的一种或多种二烯烃接触；4）在大于100℃的温度下；5）在120分钟或更短的停留时间内；6）其中第一催化剂与第二催化剂的比例为1：1至50：1；7）其中催化剂组分的活性至少为每克催化剂组分100千克聚合物；并且至少20％的烯烃转化为聚合物。
• CURABLE COMPOSITION
  申请人：KANEKA CORPORATION

  公开号：EP1024170A1

  公开（公告）日：2000-08-02

  The present invention has its object to provide a curable composition insuring a reduced stress without sacrificing restoring force and other physical properties and having a sufficient degree of adhesiveness. The present invention is related to a curable composition comprising comprising an oxyalkylene polymer having at least one reactive silicon group per molecule (A-1), an acid (B), an amine (C), and a tin-series curing catalyst (D).

  本发明的目的是提供一种可固化组合物，确保在不牺牲恢复力和其他物理性能的情况下降低应力，并具有足够的粘合力。 本发明涉及一种可固化组合物，该组合物包括每分子至少有一个活性硅基团的氧亚烃聚合物（A-1）、 一种酸 (B) 胺（C），以及 锡系列固化催化剂 (D)。
• Polyolefin adhesive compositions
  申请人：ExxonMobil Chemical Patents Inc.

  公开号：EP2261292A2

  公开（公告）日：2010-12-15

  This invention relates to an adhesive comprising a homopolypropylene or a copolymer of propylene and up to 15 mole% ethylene having an isotactic run length of 1 to 30, a percent of r dyad of greater than 20%, a heat of fusion of 70 J/g or less, and a branching index (g') of 0.90 or less.

  本发明涉及一种由均聚丙烯或丙烯与不超过 15 摩尔%乙烯的共聚物组成的粘合剂，该粘合剂具有 1 至 30 的等轴向长度、大于 20% 的 r 二聚体百分比、70 焦耳/克或更低的熔融热以及 0.90 或更低的支化指数 (g')。
• Polypropylene ethylene-propylene copolymer blends and in-line process to produce them
  申请人：ExxonMobil Research and Engineering Company

  公开号：EP2450403A1

  公开（公告）日：2012-05-09

  Isotactic polypropylene ethylene-propylene copolymer blends and in-line processes for producing them. The blend of polypropylene and ethylene-propylene copolymer may have between 1 and 50 wt% of isotactic polypropylene with a melt flow rate of between 0.5 and 20,000 g/10 min and a melting peak temperature of 145°C or higher, and wherein the difference between the DSC peak melting and the peak crystallization temperatures is less than or equal to 0.5333 times the melting peak temperature minus 41.333°C, and between 50 and 99 wt% of ethylene-propylene copolymer including between 10 wt% and 20 wt% randomly distributed ethylene with a melt flow rate of between 0.5 and 20,000 g/10 min, wherein the copolymer is polymerized by a bulk homogeneous polymerization process, and wherein the total regio defects in the continuous propylene segments of the copolymer is between 40 and 150% greater than a copolymer of equivalent melt flow rate and wt% ethylene polymerized by a solution polymerization process. The in-line process for producing the blend includes providing two or more parallel reactor trains and a separator for product blending and product-feed separation; wherein the two or more reactor trains operate under fluid phase bulk homogeneous conditions and at least one of the trains operates under supercritical conditions.

  等规聚丙烯-乙烯-丙烯共聚物混合物及其在线生产工艺。聚丙烯和乙烯-丙烯共聚物的共混物可具有 1 至 50 wt%的异构聚丙烯，其熔体流动速率为 0.5 至 20,000 g/10 min，熔融峰值温度为 145°C 或更高，其中 DSC 熔融峰值温度和结晶峰值温度之差小于或等于 0.5333 倍熔融峰值温度减去 41.333°C，以及重量百分比在 50 至 99 之间的乙烯-丙烯共聚物，其中包括重量百分比在 10 至 20 之间的无规分布乙烯，熔体流动速率在 0.5 至 20,000 g/10 min 之间，其中共聚物是通过体均聚合工艺聚合的，并且其中共聚物的连续丙烯段中的总团缺陷比通过溶液聚合工艺聚合的同等熔体流动速率和重量百分比乙烯的共聚物高 40 至 150%。生产混合物的在线工艺包括提供两个或两个以上的平行反应器系列和一个分离器，用于产品混合和产品-进料分离；其中两个或两个以上的反应器系列在流体相散装均质条件下运行，至少一个反应器系列在超临界条件下运行。