2-(4'-aminophenylethinyl)-[1,10]-phenanthroline | 869378-89-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 菲咯啉
• 英文名称: 2-(4'-aminophenylethinyl)-[1,10]-phenanthroline
• 英文别名: 4-[2-(1,10-Phenanthrolin-2-yl)ethynyl]aniline
• CAS: 869378-89-2
• 化学式: C₂₀H₁₃N₃
• 分子量: 295.343
• InChiKey: HZODWFUHAUSMMH-UHFFFAOYSA-N

物化性质

• 沸点：
  568.9±40.0 °C(Predicted)
• 密度：
  1.32±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  23
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  51.8
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  二亚乙基三胺五乙酸二酐 、 2-(4'-aminophenylethinyl)-[1,10]-phenanthroline 在 三乙胺 作用下， 以 DMF (N,N-dimethyl-formamide) 为溶剂， 反应 2.0h， 以60%的产率得到
  参考文献：
  名称：

  [DE] LANTHANOIDCHELATE UND IHRE ANWENDUNG IN DER BIOANALYTIK
  [EN] LANTHANIDE CHELATES AND USE THEREOF IN BIOANALYSIS
  [FR] CHELATES DE LANTHANIDE ET LEUR APPLICATION EN BIOANALYTIQUE

  摘要：

  公开号：

  WO2005108405A3

文献信息

• LANTHANOIDCHELATE UND IHRE ANWENDUNG IN DER BIOANALYTIK
  申请人：Sensient Imaging Technologies GmbH

  公开号：EP1732935B1

  公开（公告）日：2007-12-12
• VERFAHREN ZUM SENSITIVEN NACHWEIS VON POLYAMINOSÄUREN UND ANDEREN MAKROMOLEKÜLEN
  申请人：Xyntec Chemie Gmbh Wolfen

  公开号：EP2279415A1

  公开（公告）日：2011-02-02
• METHOD FOR THE SENSITIVE DETECTION OF POLYAMINO ACIDS AND OTHER MACRO-MOLECULES
  申请人：Hennig Horst

  公开号：US20110111388A1

  公开（公告）日：2011-05-12

  The invention relates to a method for the detection of an analyte containing polyamino acid. The object of the invention is to detect polyamino acids in a highly sensitive manner. The object is achieved in that an LM is coupled to a protein after chemical activation, and is complexed using a lanthanoid ion. In order to detect polyamino acids, the time resolved fluorescence measurement is utilized after electrophoretic separation. The detection limit is 0.5 pg per spot (bovine serum albumin), wherein the linear region extends across six orders of magnitude. The invention also relates to analytes containing nucleic acid.
• Lanthanide Chelates and Use Thereof in Bioanalysis
  申请人：Marx Jorg

  公开号：US20110136242A1

  公开（公告）日：2011-06-09

  Novel chemical compounds, with application in fluorometric analytical methods, for qualitative and quantitative determination of biomolecules. The aim of the invention is to identify and prove the suitability of such compounds. Said aim is achieved with compounds of formula (1) where R′ is an antenna function, R 2 is a chelate forming agent, containing a coordinated lanthanide(III)ion, X is —OH or a group with affinity for the biomolecule, bonded to a carboxylate group of the chelate forming agent by means of an amide bond and Y is —H or a group with affinity for the biomolecule, coupled to the antenna function.
• US8257981B2
  申请人：——

  公开号：US8257981B2

  公开（公告）日：2012-09-04