5-amino-2,2,3,3-tetrafluoro-2,3-dihydrobenzofuran | 103082-67-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 香豆素
• 英文名称: 5-amino-2,2,3,3-tetrafluoro-2,3-dihydrobenzofuran
• 英文别名: 5-amino-2,3-dihydro-2,2,3,3-tetrafluorobenzofuran；5-amino-2,2,3,3-tetrafluorobenzofuran；5-Benzofuranamine, 2,2,3,3-tetrafluoro-2,3-dihydro-；2,2,3,3-tetrafluoro-1-benzofuran-5-amine
• CAS: 103082-67-3
• 化学式: C₈H₅F₄NO
• 分子量: 207.127
• InChiKey: WYUJZLSRJRHRSK-UHFFFAOYSA-N

物化性质

• 沸点：
  232.7±40.0 °C(Predicted)
• 密度：
  1.53±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  14
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  35.2
• 氢给体数：
  1
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  5-amino-2,2,3,3-tetrafluoro-2,3-dihydrobenzofuran 、 3-(4-difluoromethoxyphenyl)-4-phenyl-2-pyrazoline 生成 N-(2,2,3,3-tetrafluorobenzofuran-5-yl)-3-(4-difluoromethoxyphenyl)-4-phenylpyrazoline-1-carboxamide
  参考文献：
  名称：

  SEELVE, DAVID E.;PLUMMER, ERNEST L.

  摘要：

  DOI：
• 作为产物：
  描述：

  2,2,3,3-tetrafluoro-2,3-dihydro-5-nitrobenzofuran 在 氧化铂 作用下， 以 甲醇 为溶剂， 以produced 2.15 g of 5-amino-2,2,3,3-tetrafluorobenzofuran的产率得到5-amino-2,2,3,3-tetrafluoro-2,3-dihydrobenzofuran
  参考文献：
  名称：

  Tetrafluoro-2,3-dihydrobenzofurans

  摘要：

  公式为##STR1##的苯并呋喃化合物，其中R.sup.1是氢、硝基、氨基、邻苯二甲酰亚胺或乙酰亚胺，R.sup.2至少是以下化合物之一：卤素、氰基、烷基（C.sub.1-C.sub.8）、环烷基（C.sub.3-C.sub.8）、羟基、烷氧基（C.sub.1-C.sub.8）、酰基（C.sub.1-C.sub.8）、酰氧基（C.sub.1-C.sub.8）、烷氧基（C.sub.1-C.sub.8）羰基、烷氧基（C.sub.1-C.sub.8）羰基烷基（C.sub.1-C.sub.8）、苯基、苯氧基、三氟甲基或二烷基（C.sub.1-C.sub.8）氨基，m为0-3，且苯环中至少有一个碳原子被取代。这些化合物是制备吡唑啉类杀虫剂的中间体。

  公开号：

  US04772730A1

文献信息

• Insecticidal urea substituted 2,3-dihydro- benzofuran and benzothiophene
  申请人：FMC Corporation

  公开号：US04636523A1

  公开（公告）日：1987-01-13

  Insecticidal compounds of the formula ##STR1## in which A and B are both halogen or hydrogen, or one of A and B is hydrogen, and the other of A and B is halogen; Z and W are independently O or S; the substituted benzofuranyl or benzothienyl group is attached at position 5 or 6; R is halogen; m is 0 to 3; R' is F or CF.sub.3 ; methods for their preparation and formulation, insecticidal compositions, and their use to control insects are disclosed.

  公式为##STR1##的杀虫化合物，其中A和B均为卤素或氢原子，或者A和B中的一个为氢原子，另一个为卤素；Z和W独立地为O或S；取代的苯并呋喃基或苯并噻吩基附着在位置5或6；R为卤素；m为0至3；R'为F或CF.sub.3；揭示了其制备和配方的方法，杀虫组合物以及其用于控制昆虫的用途。
• Tetrafluoro-2,3-dihydrobenzofurans
  申请人：FMC Corporation

  公开号：US04772730A1

  公开（公告）日：1988-09-20

  Benzofurans of the formula ##STR1## wherein R.sup.1 is hydrogen, nitro, amino, phthalimido or acetamido, R.sup.2 is at least one of halo, cyano, alkyl(C.sub.1 -C.sub.8), cycloalkyl(C.sub.3 -C.sub.8), hydroxy, alkoxy(C.sub.1 -C.sub.8), acyl(C.sub.1 -C.sub.8), acyloxy(C.sub.1 -C.sub.8), alkoxy(C.sub.1 -C.sub.8)carbonyl, alkoxy(C.sub.1 -C.sub.8)carbonylalkyl(C.sub.1 -C.sub.8), phenyl, phenyloxy, trifluoromethyl or dialkyl(C.sub.1 -C.sub.8)amino, m is 0-3, and at least one of the carbon atoms of the benzene ring of said benzofuran is substituted. The compounds are intermediates in the preparation of pyrazoline insecticides.

  公式为##STR1##的苯并呋喃化合物，其中R.sup.1是氢、硝基、氨基、邻苯二甲酰亚胺或乙酰亚胺，R.sup.2至少是以下化合物之一：卤素、氰基、烷基（C.sub.1-C.sub.8）、环烷基（C.sub.3-C.sub.8）、羟基、烷氧基（C.sub.1-C.sub.8）、酰基（C.sub.1-C.sub.8）、酰氧基（C.sub.1-C.sub.8）、烷氧基（C.sub.1-C.sub.8）羰基、烷氧基（C.sub.1-C.sub.8）羰基烷基（C.sub.1-C.sub.8）、苯基、苯氧基、三氟甲基或二烷基（C.sub.1-C.sub.8）氨基，m为0-3，且苯环中至少有一个碳原子被取代。这些化合物是制备吡唑啉类杀虫剂的中间体。
• N-[(alpha-perhaloalkylbenzyloxy)pyridyl]N'-benzoylurea insecticides
  申请人：FMC Corporation

  公开号：US05008277A1

  公开（公告）日：1991-04-16

  N-[(Alpha-perhaloalkylbenzyloxy)pyridyl]-N'-benzoylurea compounds of the following structural formula are useful insecticides: ##STR1## in which R.sub.A is selected from the group consisting of -hydrogen, -halogen, -lower alkyl, -lower alkoxy, -benzyl, and -benzyloxy; R.sub.B is selected from -hydrogen and -halogen; R.sub.C and R.sub.D are both -hydrogen or together constitute a --COCO-- bridge; R is a perhaloalkyl substitutent; R.sub.3 is selected from the group consisting of -hydrogen, -halogen and -phenylthio; R.sub.4 is selected from the group consisting of -hydrogen, -halogen, -lower alkyl, -lower alkoxy, -lower alkoxyalkyl, -lower haloalkoxy, -lower alkylthio, -lower alkylsulfonyl, and -diallylamino; or R.sub.3 and R.sub.4 at adjacent ring positions constitute a --OCH.sub.2 O--, --CH.sub.2 C(CH.sub.3).sub.2 O--, or --CF.sub.2 CF.sub.2 O-- bridge; and R.sub.5 is --hydrogen or -lower alkyl.

  以下结构式的N-[(Alpha-perhaloalkylbenzyloxy)pyridyl]-N'-benzoyl脲化合物是有用的杀虫剂：##STR1## 其中，R.sub.A从以下组中选择：-氢，-卤素，-较低烷基，-较低烷氧基，-苯甲基和-苯甲氧基；R.sub.B从-氢和-卤素中选择；R.sub.C和R.sub.D都是-氢或共同构成--COCO--桥；R是一种perhaloalkyl取代基；R.sub.3从以下组中选择：-氢，-卤素和-苯基硫；R.sub.4从以下组中选择：-氢，-卤素，-较低烷基，-较低烷氧基，-较低烷氧基烷基，-较低卤代烷氧基，-较低烷基硫基，-较低烷基磺酰基和-二烯丙基氨基；或相邻环位上的R.sub.3和R.sub.4构成--OCH.sub.2 O--、--CH.sub.2 C(CH.sub.3).sub.2 O--或--CF.sub.2 CF.sub.2 O--桥；R.sub.5是--氢或-较低烷基。
• Pyrazoline-1-carboxamides, composition containing them, and insecticidal
  申请人：FMC Corporation

  公开号：US04767779A1

  公开（公告）日：1988-08-30

  Pyrazolines of the following formula are insecticides: ##STR1## wherein R.sub.A, R.sub.B and R.sub.C are aromatic groups; R.sub.N is hydrogen or lower alkyl; and W is oxygen or sulfur.

  以下化学式的吡唑啉类化合物可用作杀虫剂：##STR1## 其中，R.sub.A、R.sub.B和R.sub.C为芳香族基；R.sub.N为氢或低碳基；W为氧或硫。
• N-[(alpha-perhaloalkylbenzyloxy)pyridyl]-N'-benzoylurea insecticides
  申请人：FMC Corporation

  公开号：US04870089A1

  公开（公告）日：1989-09-26

  N-[(Alpha-perhaloalkylbenzyloxy)pyridyl]-N'-benzoylurea compounds of the following structural formula are useful insecticides: ##STR1## in which R.sub.A is selected from the group consisting of -hydrogen, -halogen, -lower alkyl, -lower alkoxy, -benzyl, and -benzyloxy; R.sub.B is selected from -hydrogen and -halogen; R.sub.C and R.sub.D are both -hydrogen or together constitute a --COCO-- bridge; R.sub..alpha. is a perhaloalkyl substituent; R.sub.3 is selected from the group consisting of -hydrogen, -halogen and -phenylthio; R.sub.4 is selected from the group consisting of -hydrogen, -halogen, -lower alkyl, -lower alkoxy, -lower alkoxyalkyl, -lower haloalkoxy, -lower alkylthio, -lower alkylsulfonyl, and -diallylamino; or R.sub.3 and R.sub.4 at adjacent ring positions constitute a --OCH.sub.2 O--, --CH.sub.2 C(CH.sub.3).sub.2 O--, or --CF.sub.2 CF.sub.2 O-- bridge; and R.sub.5 is -hydrogen or -lower alkyl.

  以下结构式的N-[(Alpha-perhaloalkylbenzyloxy)pyridyl]-N'-benzoyl脲化合物是有用的杀虫剂：##STR1## 其中，R.sub.A从羟基，卤素，较低的烷基，较低的烷氧基，苄基和苄氧基中选择；R.sub.B从氢和卤素中选择；R.sub.C和R.sub.D都是氢或一起构成--COCO--桥；R.sub..alpha.是一种卤代烷基取代基；R.sub.3从羟基，卤素和苯基硫中选择；R.sub.4从氢，卤素，较低的烷基，较低的烷氧基，较低的烷氧基烷基，较低的卤代烷氧基，较低的烷基硫基，较低的烷基磺酰基和二烯丙基氨基中选择；或相邻环位的R.sub.3和R.sub.4构成--OCH.sub.2 O--，--CH.sub.2 C(CH.sub.3).sub.2 O--或--CF.sub.2 CF.sub.2 O--桥；R.sub.5是氢或较低的烷基。