2,2-Dichloroheptane | 65786-09-6

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 有机氯化物
• 英文名称: 2,2-Dichloroheptane
• 英文别名: 2,2-Dichlor-heptan
• CAS: 65786-09-6
• 化学式: C₇H₁₄Cl₂
• 分子量: 169.094
• InChiKey: ANINKBHZBZQOQI-UHFFFAOYSA-N

物化性质

• 熔点：
  23.5°C (estimate)
• 沸点：
  198.96°C (estimate)
• 密度：
  1.0120

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  9
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  2-庚酮 在 aluminum oxide 、 氯化亚砜 、 五氯化磷 作用下， 生成 2,2-Dichloroheptane
  参考文献：
  名称：

  Surface-Mediated Reactions. 4. Hydrohalogenation of Alkynes

  摘要：

  The use of appropriately prepared silica gel and alumina has been found to mediate the addition of hydrogen halides to alkynes. The technique has been rendered even more convenient by the use of various organic and inorganic acid halides that react in the presence of silica gel or alumina to generate hydrogen halides in situ. Treatment in this fashion of 1-propynylbenzene (1), which underwent no reaction in CH2Cl2 solution saturated with HCl, readily afforded the syn addition product, alkenyl chloride (E)-4a. On extended treatment (E)-4a underwent subsequent isomerization to the thermodynamically more stable Z isomer. Thus either isomer of 4a could be obtained in good yield depending on the reaction conditions. In a similar way bromides (E)- and (Z)-4b were obtained without competing formation of the radical products (E)- and (Z)-5, which occurred in solution. In contrast with solution-phase hydriodination of alkyne 1, which slowly afforded iodide (E)-4c, surface-mediated addition readily afforded (E)-4c, followed by isomerization to the Z isomer. E reversible arrow Z equilibration of the alkenyl halides 4 was shown to involve, at least in part, addition-elimination via the gem-dihalides 13. Analogous behavior was exhibited by the phenylalkynes 2 and 3 on surface-mediated hydrohalogenation. Surface-mediated addition of Hbr and HI to the internal alkylalkyne 14 afforded principally the anti addition products (Z)-15b,c. Treatment of the terminal alkynes 17 and 22 with (COBr)(2) over alumina gave the dibromides 20 and 24/25,respectively, whereas use of acetyl bromide as the Hbr precursor afforded the alkenyl bromides 18b and 23.

  DOI：

  10.1021/jo00090a031

文献信息

• Method for chlorinating ketones
  申请人：BASF Aktiengesellschaft

  公开号：US06337425B1

  公开（公告）日：2002-01-08

  In a process for chlorinating ketones which, apart from the carbonyl group, are inert in respect of triarylphosphine dichlorides, except for cyclopropyl methyl ketone, in which the ketones are reacted with a chlorinating agent in the presence of triarylphosphine oxides, the amount of triarylphosphine oxide is from 0.1 to 10 mol %, based on the amount of ketone. The ketones preferably have a least one CH-acid proton in the &agr; position to the carbonyl group.

  在氯化酮的过程中，除了羰基以外，在三芳基膦二氯化物方面是惰性的，除了环丙基甲基酮外，在三芳基膦氧化物的存在下，酮与氯化剂反应，三芳基膦氧化物的量为酮的量的0.1至10摩尔％。酮最好在羰基的α位置至少有一个CH-酸质子。
• Composition for curable paints
  申请人：MITSUI PETROCHEMICAL INDUSTRIES, LTD.

  公开号：EP0238327A2

  公开（公告）日：1987-09-23

  A composition for curable paints, comprising (A) l00 parts by weight of resin for curable paints, and (B) 0.5 to l0 parts by weight of chlorinated and graft-modified polypropylene which is produced by chlorinating polypropylene graft-modified with a grafting component selected from the group consisting of alpha,beta-unsaturated dicarboxylic acids, anhydrides thereof and esters thereof, and which has a chlorine content of 5 to 50% by weight, said graft-modified poly­propylene having a degree of saponification of 5 to l50 mg/g and an intrinsic viscosity [η] of 0.l to 5 dl/g. A curable paint comprising the composition and a diluent.

  一种用于固化涂料的组合物，包括 (A) 100 份（按重量计）用于固化涂料的树脂，和 (B) 0.5至l0份（重量）氯化和接枝改性聚丙烯，该聚丙烯是通过氯化聚丙烯，并用选自α，β-不饱和二羧酸、其酸酐和其酯组成的接枝组分进行接枝改性而制得，其氯含量为5至50%（重量），所述接枝改性聚丙烯的皂化度为5至l50毫克/克，固有粘度[η]为0.l 至 5 dl/g。一种可固化涂料，由该组合物和稀释剂组成。
• [DE] VERFAHREN ZUR CHLORIERUNG VON KETONEN<br/>[EN] METHOD FOR CHLORINATING KETONES<br/>[FR] PROCEDE DE CHLORATION DES CETONES
  申请人：BASF AKTIENGESELLSCHAFT

  公开号：WO1999047479A1

  公开（公告）日：1999-09-23

  (DE) In einem Verfahren zur Chlorierung von Ketonen, die abgesehen von der Carbonylgruppe in bezug auf Triarylphosphindichloride inert sind, ausgenommen Cyclopropylmethylketon, bei dem man die Ketone mit einem Chlorierungsmittel in Gegenwart von Triarylphosphinoxiden umsetzt, beträgt die Menge an Triarylphosphinoxid, bezogen auf die Menge an Keton, 01 bis 10 mol-%. Vorzugsweise weisen die Ketone in $g(a)-Stellung zur Carbonylgruppe mindestens ein CH-acides Proton auf.(EN) The invention relates to a method for chlorinating ketones which apart from the carbonyl group are inert in relation to triarylphosphine dichlorides, except cyclopropyl methyl ketone. According to said method the ketones are reacted with a chlorinating agent in the presence of triarylphosphine oxides and the quantity of triaryl phosphine oxide, in relation to the quantity of ketone, is between 0.1 and 10 mol. %. The ketones preferably have at least one CH acid proton in the $g(a) position in relation to the carbonyl group.(FR) L'invention concerne un procédé permettant de chlorer les cétones qui, en dehors du groupe carbonyle, sont inertes par rapport au dichlorure de triarylphosphine, à l'exception de la cyclopropylméthylcétone. Le procédé consiste à faire réagir les cétones avec un agent de chloration en présence de triarylphosphinoxydes, la quantité de triarylphosphinoxyde, par rapport à la quantité de cétones, étant comprise entre 0,1 et 10 mol. %. De préférence, les cétones comportent au moins un proton CH acide en position $g(a) par rapport au groupe carbonyle.

  在一种用于氯化酮的工艺中，这些酮（除了羰基外）对三苯基磷二氯化物惰性，但排除了环丙基甲酮，其中将酮与氯化试剂在三苯基磷氧化物的条件下反应，三苯基磷氧化物相对于酮的量介于0.1到10 mol-%。优先的是这些酮至少在羰基的 $g(a)-位置有一个CH 酸氢 proton。
• The Chemistry of the Acetylenes. I. The Preparation of 1-Heptyne by Dehalogenation Methods
  作者：G. Bryant Bachman、Arthur J. Hill

  DOI：10.1021/ja01327a061

  日期：1934.12
• VERFAHREN ZUR CHLORIERUNG VON KETONEN
  申请人：BASF AKTIENGESELLSCHAFT

  公开号：EP1068169A1

  公开（公告）日：2001-01-17