(1RS,2RS)-(+/-)-1,2-diphenyl-1,2-propandiol

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: (1RS,2RS)-(+/-)-1,2-diphenyl-1,2-propandiol
• 英文别名: threo-1,2-Dihydroxy-1,2-diphenyl-propan；(1RS,2RS)-1,2-diphenylpropane-1,2-diol；(+/-)-1cat_F.2t_F-diphenyl-propanediol-(1r_F.2c_F)；(1RS:2RS)-1.2-Diphenyl-propandiol-(1.2)；(+/-)-1cat_F.2t_F-Diphenyl-propandiol-(1r_F.2c_F)；(1R,2R)-1,2-diphenylpropane-1,2-diol
• 化学式: C₁₅H₁₆O₂
• 分子量: 228.291
• InChiKey: KVDNJQJZESZZST-HUUCEWRRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  17
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  (1RS,2RS)-(+/-)-1,2-diphenyl-1,2-propandiol 在 吡啶 、 锌 作用下， 生成 2,2-二苯基丙醛
  参考文献：
  名称：

  Heterogeneous reactions with zinc. II. General synthesis of ketones from 1,2-trisubstituted glycol monoesters and the mechanism of the serini reaction

  摘要：

  DOI：

  10.1021/jo00828a025
• 作为产物：
  描述：

  1-苯基-1,2-丙二酮 在 乙醚 、 硫酸 、 锌 作用下， 生成 (1RS,2RS)-(+/-)-1,2-diphenyl-1,2-propandiol
  参考文献：
  名称：

  Satellite-based mapping of Canadian boreal forest fires: Evaluation and comparison of algorithms

  摘要：

  This paper evaluates annual fire maps that were produced from NOAA-14/AVHRR imagery using an algorithm described in a companion paper (Li et al., International Journal of Remote Sensing, 21, 3057-3069, 2000 ( this issue)). Burned area masks covering the Canadian boreal forest were created by compositing the daily maps of fire hot spots over the summer and by examining Normalized Difference Vegetation Index (NDVI) changes after burning. Both masks were compared with fire polygons derived by Canadian fire agencies through aerial surveillance. It was found that the majority of fire events were captured by the satellite-based techniques, but burnt area was generally underestimated. The burn boundary formed by the fire pixels detected by satellite were in good agreement with the polygons boundaries within which, however, there were some fires missed by the satellite. The presence of clouds and low sampling frequency of satellite observation are the two major causes for the underestimation. While this problem is alleviated by taking advantage of NDVI changes, a simple combination of a hot spot technique with a NDVI method is not an ideal solution due to the introduction of new sources of uncertainty.In addition, the performance of the algorithm used in the International Geosphere-Biosphere Programme (IGBP) Data and Information System (IGBP-DIS) for global fire detection was evaluated by comparing its results with ours and with the fire agency reports. It was found that the IGBP-DIS algorithm is capable of detecting the majority of fires over the boreal forest, but also includes many false fires over old burned scars created by fires taking place in previous years. A step-by-step comparison between the two algorithms revealed the causes of the problem and recommendations are made to rectify them.

  DOI：

  10.1080/01431160050144965

文献信息

• Hot water as a mild Brønsted acid catalyst in ring opening reactions of epoxides
  作者：ZhaoBing Xu、Jin Qu

  DOI：10.1007/s11426-011-4323-x

  日期：2011.11

  Ring opening of extremely hydrophobic epoxides with water, amines, sodium azide and thiophenol was realized in the mixture solvent of water and 1, 4-dioxane under reflux condition. Hot water was believed to act as a mild Brønsted acid catalyst in the epoxide-opening reactions.

  在水和 1，4-二氧六环的混合溶剂中，在回流条件下实现了疏水性极强的环氧化物与水、胺、叠氮化钠和苯硫酚的开环反应。在环氧化物开环反应中，热水被认为是一种温和的布氏酸催化剂。
• The direction of ring opening of trans-α-methylstilbene oxide by organic acids
  作者：G. Berti、F. Bottari、B. Macchia

  DOI：10.1016/s0040-4020(01)98616-8

  日期：1964.1

  In the reaction of mesitoic acid with trans-α-methylstilbene oxide the anion adds exclusively to the tertiary carbon atom, to give the hydroxy ester of type III, which also can be prepared from α-methylbenzoin mesitoate with KBH4 and is transformed into the isomeric ester of type V by the action of alkali; the latter ester also being formed by reaction of threo-1,2-diphenyl-1,2-propanediol with mesitoyl

  在甲基磺酸与反式-α-甲基二苯乙烯氧化物的反应中，阴离子仅加到叔碳原子上，得到III型羟基酯，该羟基酯也可以由甲基丙烯酸与KBH 4的甲基磺酸安息香酸酯制得，然后转化为在碱作用下的V型异构酯；后者的酯也可通过苏-1,2-二苯基-1,2-丙二醇与甲基磺酰氯反应形成。其他酸仅产生V型酯，可能是由III型初级产物通过快速酰基转移形成的。如此制备的所有酯均属于苏氨酸系列。制备相应的赤型酯用于比较。LiA1H 4还原α-甲基安息香乙酸酯和中观酸酯 与类似地还原α-甲基安息香本身的低立体选择性相反，它仅生产苏-1,2-二苯基-1,2-丙二醇。
• Bach, Thorsten; Joedicke, Kai, Chemische Berichte, 1993, vol. 126, # 11, p. 2457 - 2466
  作者：Bach, Thorsten、Joedicke, Kai

  DOI：——

  日期：——
• Extent and Severity of Groundwater Arsenic Contamination in Bangladesh
  作者：Md. Abul Fazal、Toshihiko Kawachi、Eiji Ichion

  DOI：10.1080/02508060108686929

  日期：2001.9
• v. Auwers; Ludewig; Mueller, Justus Liebigs Annalen der Chemie, 1936, vol. 526, p. 143,170
  作者：v. Auwers、Ludewig、Mueller

  DOI：——

  日期：——