triethyl-12-mercaptododecylammonium bromide

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: triethyl-12-mercaptododecylammonium bromide
• 英文别名: 12-(Triethylazaniumyl)dodecane-1-thiolate;hydrobromide
• 化学式: Br*C₁₈H₄₀NS
• 分子量: 382.492
• InChiKey: XMRJDAFLCNJERP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  21
• 可旋转键数：
  15
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  1
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  三乙胺 、 1-溴-12-巯基十二烷 以 乙醇 为溶剂， 生成 triethyl-12-mercaptododecylammonium bromide
  参考文献：
  名称：

  Ultrasensitive Detection of CrO₄^2- Using a Microcantilever Sensor

  摘要：

  用自组装单层修饰的微悬臂梁对特定离子浓度具有灵敏的响应。在这里，我们报告了使用用三乙基-12-巯基十二烷基溴化铵自组装单层修饰的微悬臂梁检测痕量的 CrO42-。自组装单层是在一侧涂有薄层金的硅微悬臂梁上制备的。由于单层改性侧吸附了 CrO42- 离子，微悬臂梁发生弯曲。结果发现，在流动池中使用该技术可以检测到 10-9 M CrO42- 的浓度。其他阴离子，如 Cl-、Br-、CO32-（或 HCO3-）和 SO42-，对该悬臂的偏转影响很小。讨论了弯曲的力学和悬臂修改的化学原理。

  DOI：

  10.1021/ac0013103

文献信息

• GOLD THIOLATE AND PHOTOCHEMICALLY FUNCTIONALIZED MICROCANTILEVERS USING MOLECULAR RECOGNITION AGENTS
  申请人：UT-Battelle, LLC

  公开号：EP1815236A2

  公开（公告）日：2007-08-08
• Gold thiolate and photochemically functionalized microcantilevers using molecular recognition agents
  申请人：Boiadjiev I. Vassil

  公开号：US20060057026A1

  公开（公告）日：2006-03-16

  Highly sensitive sensor platforms for the detection of specific reagents, such as chromate, gasoline and biological species, using microcantilevers and other microelectromechanical systems (MEMS) whose surfaces have been modified with photochemically attached organic monolayers, such as self-assembled monolayers (SAM), or gold-thiol surface linkage are taught. The microcantilever sensors use photochemical hydrosilylation to modify silicon surfaces and gold-thiol chemistry to modify metallic surfaces thereby enabling individual microcantilevers in multicantilever array chips to be modified separately. Terminal vinyl substituted hydrocarbons with a variety of molecular recognition sites can be attached to the surface of silicon via the photochemical hydrosilylation process. By focusing the activating UV light sequentially on selected silicon or silicon nitride hydrogen terminated surfaces and soaking or spotting selected metallic surfaces with organic thiols, sulfides, or disulfides, the microcantilevers are functionalized. The device and photochemical method are intended to be integrated into systems for detecting specific agents including chromate groundwater contamination, gasoline, and biological species.
• Method of Making Gold Thiolate and Photochemically Functionalized Microcantilevers
  申请人：Boiadjiev I. Vassil

  公开号：US20080085379A1

  公开（公告）日：2008-04-10

  Highly sensitive sensor platforms for the detection of specific reagents, such as chromate, gasoline and biological species, using microcantilevers and other microelectromechanical systems (MEMS) whose surfaces have been modified with photochemically attached organic monolayers, such as self-assembled monolayers (SAM), or gold-thiol surface linkage are taught. The microcantilever sensors use photochemical hydrosilylation to modify silicon surfaces and gold-thiol chemistry to modify metallic surfaces thereby enabling individual microcantilevers in multicantilever array chips to be modified separately. Terminal vinyl substituted hydrocarbons with a variety of molecular recognition sites can be attached to the surface of silicon via the photochemical hydrosilylation process. By focusing the activating UV light sequentially on selected silicon or silicon nitride hydrogen terminated surfaces and soaking or spotting selected metallic surfaces with organic thiols, sulfides, or disulfides, the microcantilevers are functionalized. The device and photochemical method are intended to be integrated into systems for detecting specific agents including chromate groundwater contamination, gasoline, and biological species.
• US7579052B2
  申请人：——

  公开号：US7579052B2

  公开（公告）日：2009-08-25
• [EN] GOLD THIOLATE AND PHOTOCHEMICALLY FUNCTIONALIZED MICROCANTILEVERS USING MOLECULAR RECOGNITION AGENTS<br/>[FR] THIOLATE D'OR ET MICROLEVIERS FONCTIONNALISES PHOTOCHIMIQUEMENT A L'AIDE D'AGENTS DE RECONNAISSANCE MOLECULAIRE
  申请人：UT BATTELLE LLC

  公开号：WO2007011376A2

  公开（公告）日：2007-01-25

  [EN] Highly sensitive sensor plarforms for the detection of specific reagents, such as chromate, gasoline and biological species, using microcantilevers and other microelectromechanical systems (MEMS) whose surfaces have been modified with photochemically attached organic monolayers, such as self-assembled monolayers (SAM), or gold-thiol surface linkage are taught. The microcantilever sensors use photochemical hydrosilylation to modify silicon surfaces and gold-thiol chemistry to modify metallic surfaces thereby enabling individual microcantilevers in multicantilever array chips to be modified separately. Terminal vinyl substituted hydrocarbons with a variety of molecular recognition sites can be attached to the surface of silicon via the photochemical hydrosilylation process. By focusing the activating UV light sequentially on selected silicon or silicon nitride hydrogen terminated surfaces and soaking or spotting selected metallic surfaces with organic thiols, sulfides, or disulfides, the microcantilevers are funtionalized. The device and photochemical method are intended to be integrated into systems for detecting specific agents including chromate groundwater contamination, gasoline, and biological species.
  [FR] L'invention concerne des plates-formes de capteurs hautement sensibles pour la détection de réactifs spécifiques, tels que du chromate, de l'essence et des espèces biologiques, utilisant des microleviers et d'autres systèmes microélectromécaniques (MEMS) dont les surfaces ont été modifiées à l'aide de monocouches organiques fixées photochimiquement, telles que des monocouches auto-assemblées (SAM), ou une liaison de surface thiol-or. Les capteurs à microleviers utilisent l'hydrosilylation photochimique pour modifier des surfaces de silicium et la chimie thiol-or pour modifier des surfaces métalliques, permettant ainsi d'obtenir des microleviers individuels dans des puces réseau à microleviers destinées à être modifiées séparément. Des hydrocarbures vinyle substituées terminales présentant une variété de sites de reconnaissance moléculaire peuvent être fixées à la surface de silicium via le procédé d'hydrosilylation photochimique. Par focalisation de la lumière UV d'activation de manière séquentielle sur les surfaces de silicium ou de nitrure de silicium à terminaison d'hydrogène et trempage ou formation de taches sur des surfaces métalliques à l'aide de thiols, de sulfures, ou de disulfures organiques, les microleviers sont fonctionnalisés. Le dispositif et le procédé photochimique sont conçus pour être intégrés dans des systèmes de détection d'agents spécifiques comprenant une contamination d'eau souterraine par du chromate, l'essence et des espèces biologiques.