Dimethyl-2-methylcyclopentylboronat | 37981-95-6

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 硼酸衍生物
• 英文名称: Dimethyl-2-methylcyclopentylboronat
• 英文别名: Dimethoxy-(2-methylcyclopentyl)borane
• CAS: 37981-95-6
• 化学式: C₈H₁₇BO₂
• 分子量: 156.033
• InChiKey: JQVWLDGWZDLNGR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.96
• 重原子数：
  11
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  频哪醇 、 Dimethyl-2-methylcyclopentylboronat 在 4 Angstroem MS 作用下， 以 甲苯 为溶剂， 反应 12.0h， 以42%的产率得到4,4,5,5-tetramethyl-2-(2-methylcyclopentyl)-1,3,2-dioxaborolane
  参考文献：
  名称：

  Diastereoselective Reduction of Alkenylboronic Esters as a New Method for Controlling the Stereochemistry of up to Three Adjacent Centers in Cyclic and Acyclic Molecules

  摘要：

  [GRAPHIC]cis-Boronates are readily available via a diastereoselective Pd-catalyzed reduction of tetrasubstituted alkenylboronic esters using H-2. Applying the reaction conditions presented to unsaturated open-chain boronic esters allows the stereochemistry of up to three adjacent centers to be controlled.

  DOI：

  10.1021/ol0262486
• 作为产物：
  描述：

  Thexyl(2-methylcyclopentyl)boran 生成 Dimethyl-2-methylcyclopentylboronat
  参考文献：
  名称：

  Remarkably facile and selective dehydroboration of tetramethylethylene from thexylmonoalkylboranes under the influence of triethylamine. Novel, convenient synthesis of monoalkylboranes as triethylaminates

  摘要：

  DOI：

  10.1021/ja00771a059

文献信息

• Remarkably facile and selective dehydroboration of tetramethylethylene from thexylmonoalkylboranes under the influence of triethylamine. Novel, convenient synthesis of monoalkylboranes as triethylaminates
  作者：Herbert C. Brown、Eiichi Negishi、Jean Jacques Katz

  DOI：10.1021/ja00771a059

  日期：1972.8
• Diastereoselective Reduction of Alkenylboronic Esters as a New Method for Controlling the Stereochemistry of up to Three Adjacent Centers in Cyclic and Acyclic Molecules
  作者：Eike Hupe、Ilan Marek、Paul Knochel

  DOI：10.1021/ol0262486

  日期：2002.8.1

  [GRAPHIC]cis-Boronates are readily available via a diastereoselective Pd-catalyzed reduction of tetrasubstituted alkenylboronic esters using H-2. Applying the reaction conditions presented to unsaturated open-chain boronic esters allows the stereochemistry of up to three adjacent centers to be controlled.