7H-acenaphth[1,2-b]indole | 208-54-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 7H-acenaphth[1,2-b]indole
• 英文别名: 7H-Acenaphth[1,2-b]indol；Acenaphtho[1,2-b]indole；9-azapentacyclo[9.7.1.02,10.03,8.015,19]nonadeca-1(18),2(10),3,5,7,11,13,15(19),16-nonaene
• CAS: 208-54-8
• 化学式: C₁₈H₁₁N
• 分子量: 241.292
• InChiKey: UKYUPGOQZKKWDR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  19
• 可旋转键数：
  0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  15.8
• 氢给体数：
  1
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  7H-acenaphth[1,2-b]indole 在 氢氧化钾 、 硝酸 、 丙酮 作用下， 生成 6B-acetoxy-11b-nitro-6b,11b-dihydro-acenaphth[1,2-b]indole-7-carboxylic acid methyl ester
  参考文献：
  名称：

  Construction and analysis of hemin binding protein mutants in the oral pathogen Treponema denticola

  摘要：

  Treponema denticola, a periodontal pathogen, can use hemin as its sole iron source. The organism synthesizes two low-iron-induced outer-membrane hemin-binding proteins, HbpA and HbpB. To characterize genetically the function of these two novel proteins, standard recombinant DNA procedures and electroporation were used to construct T denticola strains in which the genomic copies of either hbpA or both hbpA and hbpB were interrupted with an erythromycin resistance cassette. Northern blot and RT-PCR analyses verified that the normal hbpA transcripts were missing in both mutants. The hbpA mutation also had a polar effect on the transcription of hbpB and thus neither mutant strain transcribes the downstream hbpB gene. The parental and hbp mutant strains had similar growth properties in normal media, but the mutants reached a lower cell density than parental cells in iron-restricted media. The results indicate that HbpA and/or HbpB are required for efficient iron utilization but that there is an additional system that can help T denticola acquire iron. The growth defect of the mutants was totally restored by lactoferrin but only partially restored by adding exogenous hemin or inorganic iron. Thus, hbpA and/or hhpB specifically facilitate hemin and iron utilization under low iron conditions and are presumably important for T denticola virulence in the host environment. (C) 2002 Editions scientifiques et medicales Elsevier SAS. All rights reserved.

  DOI：

  10.1016/s0923-2508(02)01370-0
• 作为产物：
  描述：

  Phenylhydrazon v.Acenaphthenon 在 盐酸 作用下， 生成 7H-acenaphth[1,2-b]indole
  参考文献：
  名称：

  Korczynski; Brydowna; Kierzek, Gazzetta Chimica Italiana, 1926, vol. 56, p. 905

  摘要：

  DOI：

文献信息

• Tandem Meinwald Rearrangement-Fischer Indolisation: A One-Pot Conversion of Epoxides into Indoles
  作者：Richard Taylor、James Donald

  DOI：10.1055/s-0028-1087476

  日期：——

  A tandem Sc(OTf)3-mediated Meinwald epoxide re­arrangement-Fischer indole synthesis is reported. Optimisation and scope and limitation studies are described. In addition, preliminary investigations to develop a telescoped epoxidation-Meinwald re­arrangement-Fischer indole sequence are outlined.

  报告了串联 Sc(OTf)3 介导的 Meinwald 环氧化物重排-费舍尔吲哚合成。报告介绍了优化、范围和限制研究。此外，还概述了为开发伸缩环氧化-Meinwald 重排-Fischer 吲哚序列而进行的初步研究。
• Compound for organic-electric element, organic-electric element using same, and electronic device for same
  申请人：DUK SAN NEOLUXCO., LTD.

  公开号：US11024812B2

  公开（公告）日：2021-06-01

  The present invention provides the compound represented by Formula 1, an organic electric element comprising a first electrode, a second electrode, and an organic material layer formed between the first electrode and the second electrode, and electronic device thereof, and by comprising the compound represented by Formula 1 in the organic material layer, the driving voltage of the organic electronic device can be lowered, and the luminous efficiency and life time of the organic electronic device can be improved.

  本发明提供了式 1 所代表的化合物、包括第一电极、第二电极和形成于第一电极与第二电极之间的有机材料层的有机电子元件及其电子装置，通过在有机材料层中加入式 1 所代表的化合物，可以降低有机电子装置的驱动电压，提高有机电子装置的发光效率和使用寿命。
• Synthesis of 1-hydroxyindoles and indoles from ortho-nitroarylethanes
  作者：Zbigniew Wróbel、Mieczyslaw Ma̧kosza

  DOI：10.1016/s0040-4020(97)00208-1

  日期：1997.4

  Cyclization of substituted ortho-nitroarylethanes to 1-hydroxyindoles and their further reduction to indoles is described. The mechanism of cyclization is discussed. (C) 1997 Elsevier Science Ltd.
• Sircar; Gopalan, Journal of the Indian Chemical Society, 1932, vol. 9, p. 297,299
  作者：Sircar、Gopalan

  DOI：——

  日期：——
• [EN] COMPOUND FOR ORGANIC-ELECTRIC ELEMENT, ORGANIC-ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE FOR SAME<br/>[FR] COMPOSÉ POUR ÉLÉMENT ORGANO-ÉLECTRIQUE, ÉLÉMENT ORGANO-ÉLECTRIQUE L'UTILISANT ET DISPOSITIF ÉLECTRONIQUE CORRESPONDANT<br/>[KO] 유기전기 소자용 화합물, 이를 이용한 유기전기소자 및 그 전자 장치
  申请人：DUK SAN NEOLUXCO LTD

  公开号：WO2017095054A1

  公开（公告）日：2017-06-08

  화학식 1로 표시되는 화합물과, 제 1전극, 제 2전극 및 제 1전극과 제 2전극 사이의 유기물층을 포함하는 유기전기소자 및 이를 포함하는 전자장치가 개시되며, 유기물층에 화학식 1로 표시되는 화합물을 포함함으로써, 유기전기소자의 구동전압을 낮출 수 있고, 발광효율 및 수명을 향상시킬 수 있다.