2,5-dihydro-5,5-dimethyl-2-methoxy-4-methylthio-1,2-oxaphosphole 2-oxide | 73332-15-7

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机膦酸及其衍生物
• 英文名称: 2,5-dihydro-5,5-dimethyl-2-methoxy-4-methylthio-1,2-oxaphosphole 2-oxide
• 英文别名: 2-methoxy-5,5-dimethyl-4-methylsulfanyl-2,5-dihydro-[1,2]oxaphosphole 2-oxide；2-Methoxy-5,5-dimethyl-4-methylsulfanyl-1,2lambda5-oxaphosphole 2-oxide；2-methoxy-5,5-dimethyl-4-methylsulfanyl-1,2λ5-oxaphosphole 2-oxide
• CAS: 73332-15-7
• 化学式: C₇H₁₃O₃PS
• 分子量: 208.218
• InChiKey: NBPVMOZRMNKISZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.3
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  60.8
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  2,5-dihydro-2,2-dimethoxy-5,5-dimethyl-4-methylthio-1,2-oxaphospholium hexachloroantimonate 在 sodium carbonate 、 potassium carbonate 作用下， 以 二氯甲烷 为溶剂， 反应 1.0h， 以64%的产率得到2,5-dihydro-5,5-dimethyl-2-methoxy-4-methylthio-1,2-oxaphosphole 2-oxide
  参考文献：
  名称：

  SULFENOCYCLIZATION REACTION OF 3-METHYL-1,2-BUTADIENEPHOSPHONATE WITH METHYL (DIMETHYLTHIO) SULFONIUM ANTIMONATE

  摘要：

  Reaction of the 3-methyl-1,2-butadienephosphonic dimethyl ester 1 with sulfenating reagents such as methylsulfenyl chloride and methyl bis(methylthio) sulfonium hexachloroantimonate (MDTSAN) has been investigated. In the case of MDTSAN, 2,5-dihydro-2,2-dimethoxy-4-methylthio-1,2-oxaphospholium hexachloroantimonate 5 was isolated. Heating or treatment of 5 with a 10% aqueous solution of a mixture of sodium and potassium carbonates lead to formation of 2,5-dihydro-4-methylthio-1,2-oxaphosphole 2-oxide 2. A possible mechanism involving formation of thiiranium and/or carbenium ions as reaction intermediates has been discussed.

  DOI：

  10.1080/10426500008043662

文献信息

• Angelov,Kh.M. et al., Journal of general chemistry of the USSR, 1979, vol. 49, p. 2152 - 2156
  作者：Angelov,Kh.M. et al.

  DOI：——

  日期：——
• Angelov, Christo M.; Vachkov, Kolyo; Petrova, Jordanka, Phosphorus and Sulfur and the Related Elements, 1982, vol. 14, p. 7 - 14
  作者：Angelov, Christo M.、Vachkov, Kolyo、Petrova, Jordanka、Kirilov, Marko

  DOI：——

  日期：——
• BUSCHMANN E.; ZEEH B., LIEBIGS ANN. CHEM., 1979, NO 10, 1585-1590
  作者：BUSCHMANN E.、 ZEEH B.

  DOI：——

  日期：——
• ANGELOV X. M.; VACHKOV K. V.; IONIN B. I.; KIRILOV M., ZH. OBSHCH. XIMII, 1979, 49, HO 11, 2438-2442
  作者：ANGELOV X. M.、 VACHKOV K. V.、 IONIN B. I.、 KIRILOV M.

  DOI：——

  日期：——
• ANGELOV, C. M.;VACHKOV, K.;PETROVA, J.;KIRILOV, M., PHOSPH. AND SULFUR, 1982, 14, N 1, 7-14
  作者：ANGELOV, C. M.、VACHKOV, K.、PETROVA, J.、KIRILOV, M.

  DOI：——

  日期：——