5-Heptylamino-2-methyl-isoindole-1,3-dione | 134276-60-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异吲哚及其衍生物
• 英文名称: 5-Heptylamino-2-methyl-isoindole-1,3-dione
• 英文别名: 5-(Heptylamino)-2-methylisoindole-1,3-dione
• CAS: 134276-60-1
• 化学式: C₁₆H₂₂N₂O₂
• 分子量: 274.363
• InChiKey: JJQLRIQHVVDPSB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  20
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  49.4
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  正庚醇 在 吡啶 、 potassium carbonate 作用下， 反应 29.0h， 生成 5-Heptylamino-2-methyl-isoindole-1,3-dione
  参考文献：
  名称：

  Synthesis of long alkyl chain mono-and di-N-substituted 4-amino-N-methylphthalimides. Comparison of N-alkylation methods

  摘要：

  4-Amino-N-methylphthalimide, 1, was N-alkylated with the respective n-alkyl sulfonates and halides. In the former case, the di-derivative 4 was favored, while in the latter case, under phase transfer catalysis, the mono-derivative 3 was predominant.

  DOI：

  10.1007/bf00809358

文献信息

• AMARILIO, DAVID S.;VARVERI, FANNIE S., MONATSH. CHEM., 122,(1991) N, C. 139-144
  作者：AMARILIO, DAVID S.、VARVERI, FANNIE S.

  DOI：——

  日期：——
• Synthesis of long alkyl chain mono-and di-N-substituted 4-amino-N-methylphthalimides. Comparison of N-alkylation methods
  作者：David S. Amarilio、Fannie S. Varveri

  DOI：10.1007/bf00809358

  日期：1991.3

  4-Amino-N-methylphthalimide, 1, was N-alkylated with the respective n-alkyl sulfonates and halides. In the former case, the di-derivative 4 was favored, while in the latter case, under phase transfer catalysis, the mono-derivative 3 was predominant.