1,2,3-trithiolane | 62601-92-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 三硫杂环戊烷
• 英文名称: 1,2,3-trithiolane
• 英文别名: trithiolane
• CAS: 62601-92-7
• 化学式: C₂H₄S₃
• 分子量: 124.252
• InChiKey: LTTGPXZEANXUSL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  5
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  75.9
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  1,2-乙二硫醇 在 硫化氢 、 三乙胺 作用下， 反应 2.0h， 以11%的产率得到1,2,3-trithiolane
  参考文献：
  名称：

  Do, Quang Tho; Elothmani, Driss; Simonet, Jacques, Bulletin de la Societe Chimique de France, 1996, vol. 133, # 3, p. 273 - 281

  摘要：

  DOI：

文献信息

• Laccase-catalyzed synthesis of 2,3-ethylenedithio-1,4-quinones
  作者：Mark D. Cannatelli、Arthur J. Ragauskas

  DOI：10.1016/j.molcatb.2015.05.016

  日期：2015.9

  Laccases (benzenediol:oxygen oxidoreductase EC 1.10.3.2) belong to the family of multicopper oxidases. These environmentally friendly enzymes require O-2 as their only co-substrate and produce H2O as their sole by-product. As a result, they have acquired increasing use in biotechnological applications, particularly in the field of organic synthesis. In the current study, laccases have been employed to successfully couple 1,2-ethanedithiol to various substituted hydroquinones to produce novel 2,3-ethylenedithio-1,4-quinones in good yields via an oxidation-addition-oxidation-addition-oxidation mechanism. The reactions proceeded in one-pot under mild conditions (room temperature, pH 5.0). This study further supports the use of laccases as green tools in organic chemistry. Furthermore, it provides evidence that laccase-catalyzed cross-coupling reactions involving small thiols are possible, in spite of research that suggests small thiols are potent inhibitors of laccases. (C) 2015 Elsevier B.V. All rights reserved.
• Do, Quang Tho; Elothmani, Driss; Simonet, Jacques, Bulletin de la Societe Chimique de France, 1996, vol. 133, # 3, p. 273 - 281
  作者：Do, Quang Tho、Elothmani, Driss、Simonet, Jacques、Guillanton, Georges Le

  DOI：——

  日期：——