3-bromo-4,5-dimethylpyrocatechol | 3938-14-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 3-bromo-4,5-dimethylpyrocatechol
• 英文别名: 3-Brom-4,5-dimethyl-brenzcatechin；3-Brom-4,5-dimethyl-brenzkatechin；3-Bromo-4,5-dimethylbenzene-1,2-diol
• CAS: 3938-14-5
• 化学式: C₈H₉BrO₂
• 分子量: 217.062
• InChiKey: INITZNGCCVPPHI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  11
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  3-bromo-4,5-dimethylpyrocatechol 在 邻四氯苯醌 作用下， 生成 3-Brom-4,5-dimethyl-o-benzochinon
  参考文献：
  名称：

  Horner; Duerckheimer, Zeitschrift fur Naturforschung, 1959, vol. 14b, p. 741

  摘要：

  DOI：
• 作为产物：
  描述：

  3,4-二甲基苯酚 在 sodium hydroxide 、 双氧水 、 溴 、 硼酸 作用下， 以 氯仿 、 甘油 为溶剂， 生成 3-bromo-4,5-dimethylpyrocatechol
  参考文献：
  名称：

  Dallacker,F. et al., Zeitschrift fur Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, 1979, vol. 34, p. 624 - 632

  摘要：

  DOI：

文献信息

• Late transition metal catalysts for olefin polymerization and oligomerization
  申请人：Cherkasov Kuzunich Vladimir

  公开号：US20060047094A1

  公开（公告）日：2006-03-02

  This invention relates to a transition metal compound represented by the formula LMX wherein M is a Group 3 to 11 metal L is a bulky bidentate or tridentate neutral ligand that is bonded to M by two or three heteroatoms and at least one heteroatom is nitrogen; X is a substituted or unsubstituted catecholate ligand provided that the substituted catecholate ligand does not contain a 1,2-diketone functionality.

  本发明涉及一种由式LMX所表示的过渡金属化合物，其中M是第3到11族金属，L是一种笨重的双或三齿中性配体，通过两个或三个杂原子与M结合，至少一个杂原子是氮；X是一种取代或未取代的邻二酚配体，但取代的邻二酚配体不含1,2-二酮官能团。
• Process for the treatment of plastic profiles
  申请人：Bayer MaterialScience AG

  公开号：EP1739119A1

  公开（公告）日：2007-01-03

  A process for treatment of the plastic profiles which is characterized in that the plastic profile, after being extruded and calibrated, is passed through a bath containing at least one additive.

  一种处理塑料型材的工艺，其特征在于塑料型材在经过挤压和校准后，要通过一个含有至少一种添加剂的浴槽。
• USE OF BROMOPHENOL-PYRAZOLINE COMPOUNDS IN THE TREATMENT OF PORCINE CORONAVIRUS DISEASES
  申请人：Shandong Linghai Biotechnology Co., Ltd.

  公开号：EP4014975A1

  公开（公告）日：2022-06-22

  The invention belongs to the technical field of medicine, and particularly relates to use of bromophenol-pyrazoline compounds in the treatment of porcine coronavirus diseases. Through the research in the invention, it is found that the bromophenol-pyrazoline compounds inhibit replication of porcine coronaviruses at a cellular level, and can treat porcine coronavirus diseases (such as PEDV and TGEV) in clinical trials, greatly improving the survival rate of infected piglets, so the compounds can be used to prepare drugs for treating porcine coronavirus diseases.

  本发明属于医药技术领域，尤其涉及溴酚吡唑啉化合物在治疗猪冠状病毒疾病中的用途。通过本发明的研究发现，溴酚吡唑啉化合物在细胞水平上抑制猪冠状病毒的复制，在临床上可以治疗猪冠状病毒病（如PEDV和TGEV），大大提高了感染仔猪的存活率，因此该化合物可用于制备治疗猪冠状病毒病的药物。
• Organic photochromic compositions of improved kinetic performance
  申请人：——

  公开号：US20030045612A1

  公开（公告）日：2003-03-06

  Described are imbibition compositions that incorporate kinetic enhancing additive(s) into photochromic polymeric host material. Kinetic enhancing additives include organic polyol(s), epoxy-containing compound(s) or a mixture thereof that improves the performance of organic photochromic compounds in the polymeric host as determined in the Photochromic Performance Test. Also described is a process for incorporating kinetic enhancing additives into polymeric substrates prior to, after and/or with organic photochromic compounds and the resulting photochromic articles produced by such a process.

  所述的浸泡组合物在光致变色聚合主材料中加入了动力学增强添加剂。动力学增强添加剂包括有机多元醇、含环氧化合物或它们的混合物，这些添加剂可改善聚合物主材料中有机光致变色化合物的性能，如在光致变色性能测试中确定的那样。此外，还描述了一种在有机光致变色化合物之前、之后和/或与有机光致变色化合物一起将动力学增强添加剂加入聚合物基质中的工艺，以及通过这种工艺生产的光致变色物品。
• Articles having a photochromic polymeric coating
  申请人：——

  公开号：US20030143404A1

  公开（公告）日：2003-07-31

  Described is a photochromic article that includes a substrate and at least a partial coating of an at least partially cured polymerizable composition of a photochromic amount of at least one photochromic compound, at least one material having at least one carbonate group and at least one hydroxyl group, and at least one monoisocyanate containing material having at least one unsaturated group. Also described are photochromic optical elements such as ophthalmic lenses, prepared from an optical element substrate coated with the photochromic polymerizable composition.

  描述了一种光致变色制品，该制品包括基底和至少部分涂覆的至少部分固化的可聚合组合物，该组合物包含至少一种光致变色化合物的光致变色量、至少一种具有至少一个碳酸酯基团和至少一个羟基的材料，以及至少一种具有至少一个不饱和基团的含单异氰酸酯的材料。此外，还描述了由涂有光致变色可聚合组合物的光学元件基材制备的光致变色光学元件，如眼科透镜。