5-(naphthalen-1-yl)benzene-1,3-diol | 881888-23-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 5-(naphthalen-1-yl)benzene-1,3-diol
• 英文别名: 5-Naphthalen-1-ylbenzene-1,3-diol
• CAS: 881888-23-9
• 化学式: C₁₆H₁₂O₂
• 分子量: 236.27
• InChiKey: HMRRMIAVEBCCMB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  18
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  5-(naphthalen-1-yl)benzene-1,3-diol 在 三氟化硼乙醚 、 对甲苯磺酸 作用下， 以 二氯甲烷 、 苯 为溶剂， 生成 (6aR,10aR)-6,6,9-trimethyl-3-(naphthalen-1-yl)-6a,7,10,10a-tetrahydro-6H-benzo[c]chromen-1-ol
  参考文献：
  名称：

  Structural modifications of the cannabinoid side chain towards C3-aryl and 1′,1′-cycloalkyl-1′-cyano cannabinoids

  摘要：

  The compounds reported in this study are Delta(8)-THC analogues in which the C3 five-carbon linear side chain of Delta(8)-THC was replaced with aryl and 1',1'-cycloalkyl substituents. Of the compounds described here analogues 2d (CB1, K-i = 11.7 nM. CB2, K-i = 9.39 nM) and 2f (CB1, K-i = 8.26 nM. CB2, K-i = 3.86 nM) exhibited enhanced binding affinities for CB1 and CB2, exceeding that of Delta(8)-THC. Efficient procedures for the synthesis of these novel cannabinoid analogues are described. (C) 2006 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2005.12.026
• 作为产物：
  描述：

  1-(3',5'-dimethoxyphenyl)naphthalene 在 三溴化硼 作用下， 以 二氯甲烷 为溶剂， 反应 12.0h， 以46%的产率得到5-(naphthalen-1-yl)benzene-1,3-diol
  参考文献：
  名称：

  间苯二酚的手性双核钒配合物介导的氧化偶联。

  摘要：

  通过在空气中使用二溴化二核钒（V）催化剂1c，建立了间苯二酚的高度区域和对映选择性氧化偶联的方法。当将带有芳基取代基的间苯二酚作为底物用于偶联时，可以以高达98％ee的高收率获得轴向手性双间苯二酚作为单一的区域异构体。

  DOI：

  10.1021/acs.joc.8b02494

文献信息

• NOVEL ARYL ESTER COMPOUND, ITS PRODUCTION PROCESS , EPOXY RESIN COMPOSITION USING SAID COMPOUND, AND COPPER-CLAD LAMINATE USING THE EPOXY RESIN COMPOSITION
  申请人：——

  公开号：US20020010288A1

  公开（公告）日：2002-01-24

  An aryl ester compound composed of a polyhydric phenol in which at least one OH group has been esterified with an organic acid or its derivatives having 1 to 20 carbon atoms, said polyhydric phenol being the condensation product of a phenolic compound represented by the general formula: 1 with a carbonyl compound represented by the general formula: 2 which aryl ester compound can give, when used as a curing agent for an epoxy resin, a cured product having a low dielectric constant and a low dielectric loss tangent; an epoxy resin composition comprising as the essential components an epoxy resin, said aryl ester compound and a cure accelerator; and a copper-clad laminate using the epoxy resin composition. The copper-clad laminate has a low dielectric constant and a low dielectric loss tangent and is excellent in adhesiveness as compared with conventional ones, and hence, is suitable for multilayer printed wiring board for high speed operation, especially at high-frequency region.

  一种芳基酯化合物，由多水酚组成，其中至少有一个羟基与具有 1 至 20 个碳原子的有机酸或其衍生物酯化，所述多水酚是通式所代表的酚类化合物的缩合产物： 1 的羰基化合物的缩合产物： 2 该芳基酯化合物用作环氧树脂的固化剂时，可得到具有低介电常数和低介电损耗正切的固化产品；环氧树脂组合物，其主要成分包括环氧树脂、上述芳基酯化合物和固化促进剂；以及使用该环氧树脂组合物的覆铜板。与传统层压板相比，覆铜层压板具有低介电常数和低介电损耗正切，粘合性极佳，因此适用于高速运行的多层印刷线路板，特别是在高频区域。
• Novel ester compound and thermosetting resin composition using the same
  申请人：Sumitomo Chemical Company, Limited

  公开号：EP0811619B1

  公开（公告）日：2000-09-27
• Aryl ester compound, its production process, epoxy resin composition using said compound, and copper-clad laminate using the epoxy resin composition
  申请人：SUMITOMO CHEMICAL COMPANY LIMITED

  公开号：EP0699670B1

  公开（公告）日：2002-03-06
• US5726257A
  申请人：——

  公开号：US5726257A

  公开（公告）日：1998-03-10
• US5916683A
  申请人：——

  公开号：US5916683A

  公开（公告）日：1999-06-29