N,N'-dimethyl-but-2t-ene-1,4-diamine | 59824-12-3

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N,N'-dimethyl-but-2t-ene-1,4-diamine
• 英文别名: 2-Butene-1,4-diamine, N,N'-dimethyl-；(E)-N,N'-dimethylbut-2-ene-1,4-diamine
• CAS: 59824-12-3
• 化学式: C₆H₁₄N₂
• 分子量: 114.191
• InChiKey: QXDVFQAKOKIPCM-ONEGZZNKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.3
• 重原子数：
  8
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  24.1
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2,2-双-(4-甘胺氧苯)丙烷 、 N,N'-dimethyl-but-2t-ene-1,4-diamine 以 Petroleum ether 、 苯 为溶剂， 生成 2,2,8,13-tetramethyl-4,17-dioxa-8,13-diaza-1,3(1,4)-dibenzena-cycloheptadecaphan-10t-ene-6,15-diol
  参考文献：
  名称：

  Ore,S.; Tjugum,O.G., Acta Chemica Scandinavica (1947), 1970, vol. 24, p. 2397 - 2407

  摘要：

  DOI：

文献信息

• Materials for inducing alignment in liquid crystal and liquid crystal displays
  申请人：——

  公开号：US20010039361A1

  公开（公告）日：2001-11-08

  The present invention provides novel aromatic diamines useful in preparing polyimides for optical alignment layers in liquid crystal displays. The novel compositions comprise side-chains general formula I -L 1 -D-L 2 -C f wherein D comprises 1 to 4 carbon-carbon double bonds, C f is a monovalent C 4 to C 20 fluorocarbon radical and L 1 and L 2 are linking groups.

  本发明提供了一种新型芳香二胺，用于制备液晶显示器中的光学调向层的聚酰亚胺。这种新型组合物包括侧链通式I -L 1 -D-L 2 -C f 其中D包括1至4个碳-碳双键，C f 是一种一价的C 4 至C 20 氟碳基团，L 1 和L 2 是连接基团。
• Chiral Phosphoramidites
  申请人：Reetz Manfred T.

  公开号：US20080207942A1

  公开（公告）日：2008-08-28

  Phosphoramidites with the general formulae I to VI are claimed together with the use of these compounds as ligands of transition metal compounds, in particular in transition metal catalysts, in the hydrogenation, transfer hydrogenation, hydroboration, hydrocyanation, 1,4-addition, hydroformylation, hydrosilylation, hydrovinylation, and Heck reactions of prochiral olefins, ketones, or ketimines.

  主张具有一般公式I至VI的磷酰胺酯，以及将这些化合物用作过渡金属化合物的配体，特别是在过渡金属催化剂中，在顺反式烯烃、酮或酮亚胺的氢化、转移氢化、氢硼化、氢氰化、1,4-加成、羰基化、硅烷化、氢乙烯化和Heck反应中。
• Novel antibacterial agents
  申请人：Christensen G. Burton

  公开号：US20070134729A1

  公开（公告）日：2007-06-14

  This invention relates to novel multibinding compounds (agents) that are antibacterial agents. The multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands in their monovalent (i.e., unlinked) state have the ability to bind to a an enzyme involved in cell wall biosynthesis and metabolism, a precursor used in the synthesis of the bacterial cell wall and/or the bacterial cell surface thereby interfere with the synthesis and/or metabolism of the cell wall. In particular the multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands has a ligand domain capable of binding to penicillin binding proteins, a transpeptidase enzyme, a substrate of a transpeptidase enzyme, a beta-lactamase enzyme, pencillinase enzyme, cephalosporinase enzyme, a transglycoslase enzyme, or a transglycosylase enzyme substrate; Preferably, the ligands are selected from the beta lactam or glycopeptide class of antibacterial agents.

  本发明涉及一种新型多结合化合物（药剂），其为抗菌剂。该发明的多结合化合物由2-10个配体通过连接剂或连接剂共价连接而成，其中每个单价（即未连接的）配体具有与细胞壁生物合成和代谢中的酶、合成细菌细胞壁和/或细菌细胞表面的前体有结合能力，从而干扰细胞壁的合成和/或代谢。特别地，本发明的多结合化合物由2-10个配体通过连接剂或连接剂共价连接而成，其中每个配体具有能够结合青霉素结合蛋白、横向肽酶酶、横向肽酶酶底物、β-内酰胺酶、青霉素酶、头孢菌素酶、横向转移酶酶或横向转移酶酶底物的配体结构域。优选地，配体选自β-内酰胺类或糖肽类抗菌剂。
• Materials for inducing alignment in liquid crystals and liquid crystal displays
  申请人：——

  公开号：US20010018099A1

  公开（公告）日：2001-08-30

  The present invention provides novel polyimides, poly(amic acids) and poly(amide esters) thereof, and optical alignment layers derived therefrom, for inducing alignment of liquid crystals and liquid crystal displays. The novel compositions comprise side-chain polymers of the general formula I —L 1 —D—L 2 —C f wherein D comprises 1 to 4 carbon-carbon double bonds, C f is a monovalent C 4 to C 20 fluorocarbon radical and L 1 and L 2 are linking groups. The invention further describes liquid crystal displays and other liquid crystal devices.

  本发明提供了新型聚酰亚胺、聚酰胺酸和聚酰胺酯，以及由此衍生的光学对准层，用于诱导液晶和液晶显示器的对准。这些新型组合物包括具有以下一般式I—L1—D—L2—Cf的侧链聚合物，其中D包括1到4个碳-碳双键，Cf是一价的C4到C20氟碳基，L1和L2是连接基。本发明进一步描述了液晶显示器和其他液晶器件。
• Beta2-adrenergic receptor agonists
  申请人：Moran J. Edmund

  公开号：US20070179179A1

  公开（公告）日：2007-08-02

  Disclosed are multibinding compounds which are β2 adrenergic receptor agonists and are useful in the treatment and prevention of respiratory diseases such as asthma, bronchitis. They are also useful in the treatment of nervous system injury and premature labor.

  本发明涉及多重结合化合物，其为β2肾上腺素能受体激动剂，可用于治疗和预防哮喘、支气管炎等呼吸系统疾病。它们还可用于治疗神经系统损伤和早产。