N,N-dimethyl-4-(pyrimidin-2-yl)aniline | 1440252-93-6

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N,N-dimethyl-4-(pyrimidin-2-yl)aniline
• 英文别名: N,N-dimethyl-4-pyrimidin-2-ylaniline
• CAS: 1440252-93-6
• 化学式: C₁₂H₁₃N₃
• 分子量: 199.255
• InChiKey: RJJJWZAJSLSBKC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  29
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  2-氯嘧啶 、 4-二甲基氨基苯硼酸 在 四(三苯基膦)钯 、 sodium carbonate 作用下， 以 1,4-二氧六环 、 水 为溶剂， 反应 0.5h， 生成 N,N-dimethyl-4-(pyrimidin-2-yl)aniline
  参考文献：
  名称：

  Small-molecule pyrimidine inhibitors of the cdc2-like (Clk) and dual specificity tyrosine phosphorylation-regulated (Dyrk) kinases: Development of chemical probe ML315

  摘要：

  Substituted pyrimidine inhibitors of the Clk and Dyrk kinases have been developed, exploring structure-activity relationships around four different chemotypes. The most potent compounds have low-nanomolar inhibitory activity against Clk1, Clk2, Clk4, Dyrk1A and Dyrk1B. Kinome scans with 442 kinases using agents representing three of the chemotypes show these inhibitors to be highly selective for the Clk and Dyrk families. Further off-target pharmacological evaluation with ML315, the most selective agent, supports this conclusion. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2013.02.096

文献信息

• COLORED RESIN COMPOSITIONS FOR COLOR FILTER, COLOR FILTER, ORGANIC EL DISPLAY, AND LIQUID-CRYSTAL DISPLAY DEVICE
  申请人：SAKO Naoki

  公开号：US20110049444A1

  公开（公告）日：2011-03-03

  A colored resin composition is provided which is capable of providing blue pixels of a color filter that have excellent light resistance and which satisfies heat resistance required in color display production steps. A color filter having blue pixels with excellent color purity and transmittance and an organic EL display and a liquid-crystal display device both having satisfactory blue purity are also provided by using the colored resin composition. The colored resin composition for color filter includes (a) a binder resin, (b) a solvent, and a triarylmethane type coloring matter of a specific structure represented by general formula (I). The color filter, organic EL display, and liquid-crystal display device are produced using the colored resin composition.

  提供了一种彩色树脂组合物，能够提供具有优异光稳定性的蓝色像素的颜色滤光片，并满足彩色显示生产步骤所需的耐热性。通过使用该彩色树脂组合物，还提供了具有优异色纯度和透过率的蓝色像素的颜色滤光片，以及具有令人满意的蓝色纯度的有机EL显示器和液晶显示器设备。颜色滤光片的彩色树脂组合物包括（a）粘合剂树脂，（b）溶剂，以及由通式（I）表示的具有特定结构的三芳基甲烷型着色物。使用该彩色树脂组合物制备了颜色滤光片、有机EL显示器和液晶显示器设备。
• Photopolymerizable composition
  申请人：MITSUBISHI KASEI CORPORATION

  公开号：EP0138187A2

  公开（公告）日：1985-04-24

  A photopolymerizable composition comprising an addition-polymerizable compound having at least one ethylenically unsaturated double bond and a photopolymerization initiator, characterized in that the initiator comprises (a) a compound of the formula: wherein R1 and R2 are alkyl group, n is 1, 2 or 3 and ring A is an aromatic ring containing nitrogen atom, and (b) hexaarylbiimidazole. The initiator may additionally contain a thiol of the formula: wherein Z is -0-, -S- or -NH-. The composition is not only highly sensitive to ultraviolet ray but also highly stable in storage.

  一种可光聚合的组合物，包括至少有一个乙烯不饱和双键的可加成聚合的化合物和一种光聚合引发剂，其特征在于引发剂包括(a)式中R1和R2为烷基，n为1、2或3，环A为含氮原子的芳香环的化合物，和(b)六芳基比咪唑。 引发剂还可含有式中Z为-0-、-S-或-NH-的硫醇。 该组合物不仅对紫外线高度敏感，而且在储存中高度稳定。
• POLYMERIZABLE COMPOSITION FOR COLOR FILTER
  申请人：MITSUBISHI CHEMICAL CORPORATION

  公开号：EP0758097A1

  公开（公告）日：1997-02-12

  The present invention provides a polymerizable composition for a color filter, which comprises a (meth)acrylate copolymer containing alicyclic (meth)acryloyl groups in its side chains, a compound having at least one ethylenically unsaturated double bond, a photopolymerization initiator and a colorant, a color filter obtained by coating the composition on a glass substrate, followed by exposure and development; and a method for producing a color filter, which comprises coating the composition on a glass substrate, followed by exposure and development. The polymerizable composition of the present invention is highly sensitive and excellent in chemical resistance. Accordingly, according to the present invention, it is possible to produce a color filter of a high quality without a protective layer such as an oxygen-shielding film.

  本发明提供了一种用于彩色滤光片的可聚合组合物，该组合物包括侧链中含有脂环族（甲基）丙烯酰基的（甲基）丙烯酸酯共聚物、具有至少一个乙烯不饱和双键的化合物、光聚合引发剂和着色剂；通过将该组合物涂在玻璃基板上，然后进行曝光和显影而获得彩色滤光片；以及一种生产彩色滤光片的方法，该方法包括将该组合物涂在玻璃基板上，然后进行曝光和显影。 本发明的可聚合组合物具有高灵敏度和优异的耐化学性。因此，根据本发明，可以在不使用氧屏蔽膜等保护层的情况下生产出高质量的彩色滤光片。
• BLUE COLOR COMPOSITION FOR COLOR FILTER, COLOR FILTER, AND COLOR IMAGE DISPLAY DEVICE
  申请人：Mitsubishi Chemical Corporation

  公开号：EP1742096A1

  公开（公告）日：2007-01-10

  To provide a blue composition for a color filter which realizes an image with a high color purity, a color filter and a color image display device. A color image display device comprising a combination of light bulbs, a color filter having color elements of at least three colors of red, green and blue corresponding to the light bulbs, and a backlight for transmission illumination, wherein the backlight contains a LED in its structure, and under the following definitions: λn nm represents a wavelength at every interval of 5 nm in the visible light range of from 380 to 780 nm; TR(λn) a spectral transmittance (%) at a wavelength λn nm by a red pixel of the color filter; and I(λn) a relative emission intensity, normalized by a total emission intensity, at a wavelength λn nm from the backlight, these satisfy the following condition (1): I⁢620-680×TR⁢620-680≧1.1

  提供一种可实现高色彩纯度图像的彩色滤光片的蓝色成分、彩色滤光片和彩色图像显示装置。 一种彩色图像显示装置，包括灯泡组合、具有与灯泡相对应的至少红、绿、蓝三种颜色的彩色元件的彩色滤光片，以及用于透射照明的背光灯，其中背光灯的结构中包含一个发光二极管，并根据以下定义：λn nm 表示在 380 至 780 nm 的可见光范围内每间隔 5 nm 的波长；TR(λn) 彩色滤光片的红色像素在波长 λn nm 处的光谱透过率 (%)；I(λn) 背光灯在波长 λn nm 处的相对发射强度，按总发射强度归一化，这些满足以下条件 (1)：I⁢620-680×TR⁢620-680≧1.1
• LCD backlight containing a LED with adapted light emission and suitable colour filters
  申请人：Mitsubishi Chemical Corporation

  公开号：EP2078978A2

  公开（公告）日：2009-07-15

  To provide a blue composition for a color filter which realizes an image with a high color purity, a color filter and a color image display device. A color image display device comprising a combination of light bulbs, a color filter having color elements of at least three colors of red, green and blue corresponding to the light bulbs, and a backlight for transmission illumination, wherein the backlight contains a LED in its structure, and under the following definitions: λn nm represents a wavelength at every interval of 5 nm in the visible light range of from 380 to 780 nm; TR(λn) a spectral transmittance (%) at a wavelength λn nm by a red pixel of the color filter; and I(λn) a relative emission intensity, normalized by a total emission intensity, at a wavelength λn nm from the backlight, these satisfy the following condition (1): I620-680×TR⁢620-680≧1.1

  提供一种可实现高色彩纯度图像的彩色滤光片的蓝色成分、彩色滤光片和彩色图像显示装置。 一种彩色图像显示装置，包括灯泡组合、具有与灯泡相对应的至少红、绿、蓝三种颜色的彩色元件的彩色滤光片，以及用于透射照明的背光灯，其中背光灯的结构中包含一个发光二极管，并根据以下定义：λn nm 表示在 380 至 780 nm 的可见光范围内每间隔 5 nm 的波长；TR(λn) 彩色滤光片的红色像素在波长 λn nm 处的光谱透过率 (%)；I(λn) 背光灯在波长 λn nm 处的相对发射强度，按总发射强度归一化，这些满足以下条件 (1)：I620-680×TR⁢620-680≧1.1