2-[4-(2,4-dichlorobenzyloxy)phenyl]ethanol | 61292-78-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 2-[4-(2,4-dichlorobenzyloxy)phenyl]ethanol
• 英文别名: 4-(2,4-Dichlorobenzyloxy)-phenethyl alcohol；2-[4-[(2,4-dichlorophenyl)methoxy]phenyl]ethanol
• CAS: 61292-78-2
• 化学式: C₁₅H₁₄Cl₂O₂
• 分子量: 297.181
• InChiKey: RBRCNZWYHCTYET-UHFFFAOYSA-N

物化性质

• 熔点：
  55 °C(Solv: cyclohexane (110-82-7))
• 沸点：
  431.3±40.0 °C(Predicted)
• 密度：
  1.301±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  19
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-[4-(2,4-dichlorobenzyloxy)phenyl]ethanol 、 氯化亚砜 、 咪唑钠 以39%的产率得到
  参考文献：
  名称：

  STREHLKE P.; KESSLER H. J., EUR. J. MED. CHEM.-CHIM. THER., 1979, 14, NO 3, 238-242

  摘要：

  DOI：
• 作为产物：
  描述：

  对羟基苯乙醇 、 2,4-二氯氯苄 在 sodium hydroxide 作用下， 以 乙醇 为溶剂， 生成 2-[4-(2,4-dichlorobenzyloxy)phenyl]ethanol
  参考文献：
  名称：

  Strehlke; Kessler, European Journal of Medicinal Chemistry, 1979, vol. 14, # 3, p. 238 - 242

  摘要：

  DOI：

文献信息

• Amino-, mercapto- and -oxy-substituted-phenyl and -phenalkyl imidazoles
  申请人：Schering Aktiengesellschaft

  公开号：US04006243A1

  公开（公告）日：1977-02-01

  Compounds of the formula ##STR1## wherein Z is a direct bond or alkylene of 1 - 3 carbon atoms which is unsubstituted or substituted on the carbon atom alpha to the phenyl group by alkyl or unsubstituted or substituted phenyl, R.sub.2 and R.sub.3 singly are H, alkyl, alkoxy, alkylmercapto, halo, nitro or, collectively, C.sub.4 H.sub.4, and R.sub.4 is alkenyl, alkinyl, unsubstituted or substituted phenyl or phenylalkyl, or, when Z is substituted methylene, also alkyl, are useful in combating Germatophyte infections, especially Trichophyton rubrum and mentagrophytes, and yeast infections, especially Candida albicans, as well as bacterial and fungal infections.

  分子式为##STR1##的化合物，其中Z是直接键或1-3个碳原子的烷基，该烷基未取代或在与苯基相邻的碳原子上被烷基或未取代或取代的苯基取代，R.sub.2和R.sub.3分别是H、烷基、烷氧基、烷硫基、卤素、硝基或C.sub.4H.sub.4，R.sub.4是烯基、炔基、未取代或取代的苯基或苯基烷基，或当Z是取代的亚甲基时，也可以是烷基。这些化合物对抗真菌感染特别是红色毛癣菌和小鼠癣菌，以及酵母感染特别是白色念珠菌，以及细菌和真菌感染都有用。
• REVERSIBLY THERMOCHROMIC COMPOSITION
  申请人：Kabushiki Kaisha Pilot Corporation

  公开号：EP2772523A1

  公开（公告）日：2014-09-03

  [Object] To provide a reversibly thermochromic composition free from accidental discoloration by heat conducting from the opposite side writing surface or by self-heating due to quick writing; and also to provide a solid writing material and a writing ink composition comprising that composition. [Means to solve the problem] A reversibly thermochromic composition comprising a combination of: (a) a reversibly thermochromic component capable of being discolored or decolored by heat and (b) a component for controlling heat conducting to the reversibly thermochromic component; and also a solid writing material and a writing ink composition comprising that composition.

  [目的]提供一种可逆热致变色组合物，该组合物不会因反面书写面的热传导或快速书写导致的自热而意外变色；还提供一种固体书写材料和包含该组合物的书写墨水组合物。 [解决问题的方法] 一种可逆热致变色组合物，由以下物质组合而成：(a) 能够受热变色或脱色的可逆热致变色成分和 (b) 用于控制热量传导至可逆热致变色成分的成分；以及包含该成分的固体书写材料和书写墨水组合物。
• SOLID WRITING MATERIAL
  申请人：Kabushiki Kaisha Pilot Corporation

  公开号：EP2957608A1

  公开（公告）日：2015-12-23

  The invention aims at providing a solid writing material having a good color changing property or color extinguishing property, and having an excellent light resistance, moldability and strength. The solid writing material includes an inner core usable for writing and an outer shell covering an outer peripheral surface of the inner core; the inner core including a reversible thermochromic microcapsuled pigment encapsulating a temperature-sensitive color-changeable color-memorizing composition and an excpient; the temperature-sensitive color-changeable color-memorizing composition including at least (a) an electron-donating coloring organic compound, (b) an electron accepting compound and (c) a reaction medium effecting reversibly an electron transfer reaction between the (a) and (b) components in a specific temperature range; the outer shell including a filler.

  本发明旨在提供一种固体书写材料，该材料具有良好的变色性能或褪色性能，并具有优异的耐光性、成型性和强度。该固体书写材料包括一个可用于书写的内芯和一个覆盖内芯外周表面的外壳；内芯包括一个可逆热致变色微胶囊颜料，其中封装了一种对温度敏感的可变色记色组合物和一种赋形剂；感温变色记色组合物至少包括(a)一种电子捐赠着色有机化合物，(b)一种电子接受化合物和(c)一种反应介质，在特定温度范围内可逆地影响(a)和(b)组分之间的电子转移反应；外壳包括填料。
• REVERSIBLE THERMOCHROMIC COMPOSITION, REVERSIBLE THERMOCHROMIC MICROCAPSULE PIGMENT COMPRISING SAME, AND WRITING INSTRUMENT USING SAME
  申请人：THE PILOT INK CO., LTD.

  公开号：EP3950068A1

  公开（公告）日：2022-02-09

  [Problems] Provided are a highly marketable reversibly thermochromic composition that provides a black color during color development by using a fluoran derivative having a specific structure as an electron-donating color-developing organic compound, turns colorless during decoloration, and is excellent in contrast between a colored state and a decolored state and a microcapsule pigment encapsulating the same. [Solution] Disclosed are a reversibly thermochromic composition including: (a) a fluoran derivative having a specific structure as an electron-donating color-developing organic compound; (b) an electron-accepting compound; and (c) a reaction medium which reversibly induces an electron transfer reaction between the component (a) and the component (b) in a specific temperature range, and a reversibly thermochromic microcapsule pigment encapsulating the same.

  [问题]提供了一种极具市场前景的可逆热致变色组合物，该组合物通过使用具有特定结构的芴衍生物作为电子捐赠显色有机化合物，在显色过程中提供黑色，在脱色过程中变成无色，并且在有色状态和脱色状态之间具有极佳的对比度，同时还提供了封装该组合物的微胶囊颜料。 [解决方案]本发明公开了一种可逆热变色组合物，包括：（a）具有特定结构的氟烷衍生物，作为电子捐赠显色有机化合物；（b）电子接受化合物；以及（c）反应介质，该介质可在特定温度范围内可逆地诱导组分（a）和组分（b）之间的电子转移反应，以及封装该组合物的可逆热变色微胶囊颜料。
• REVERSIBLY THERMOCHROMIC AQUEOUS INK COMPOSITION, AND WRITING INSTRUMENT AND WRITING INSTRUMENT SET EACH UTILIZING SAME
  申请人：THE PILOT INK CO., LTD.

  公开号：EP2468828B1

  公开（公告）日：2016-11-30