4-((2-chlorophenylimino)methyl)-N,N-dimethylaniline | 110915-77-0

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 4-((2-chlorophenylimino)methyl)-N,N-dimethylaniline
• 英文别名: 2-chloro-N-[4-(dimethylamino)benzylidene]aniline；4-dimethylaminobenzylidene-2-chloroaniline；Benzenamine, 4-[[(2-chlorophenyl)imino]methyl]-N,N-dimethyl-；4-[(2-chlorophenyl)iminomethyl]-N,N-dimethylaniline
• CAS: 110915-77-0
• 化学式: C₁₅H₁₅ClN₂
• 分子量: 258.75
• InChiKey: PIYOJDWSJRFVDM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  18
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.13
• 拓扑面积：
  15.6
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  4-((2-chlorophenylimino)methyl)-N,N-dimethylaniline 在 盐酸 作用下， 以 solid 为溶剂， 生成 4-dimethylaminobenzylidene-2-chloroaniline HCl complex
  参考文献：
  名称：

  Hadjoudis, E., Molecular Crystals and Liquid Crystals (1969-1991), 1986, vol. 137, p. 17 - 28

  摘要：

  DOI：
• 作为产物：
  描述：

  对氨基苯甲醛 、 邻氯苯胺 在 溶剂黄146 作用下， 以 乙醇 为溶剂， 反应 8.0h， 以77%的产率得到4-((2-chlorophenylimino)methyl)-N,N-dimethylaniline
  参考文献：
  名称：

  Synthesis, crystal growth and spectroscopic investigation of second order organic nonlinear optical single crystal: 2-Chloro-N-[4-(dimethylamino)benzylidene]aniline

  摘要：

  Organic nonlinear optical (NLO) crystal 2-chloro-N-14-(dimethylamino)benzylidene]aniline (2CI4DBA) was synthesized and grown by restricted slow evaporation technique at room temperature using acetone as solvent with good degree of transparency. The lattice parameters were determined and found to be noncentrosymmetric orthorhombic system by single crystal X-ray diffraction. The crystalline nature of the synthesized material was recorded by the powder X-ray diffraction pattern. Molecular structure of the grown crystal was investigated by 1H and 13C NMR and functional groups were identified by FTIR spectrum analysis. The optical absorbance of the grown crystal was ascertained by recording UV Visible spectrum. Thermal and physiochemical stability of the grown material was investigated by TG/DTA analysis. SHG efficiency was determined by Kurtz Perry Powder SHG technique and found to be 4.2 and 1.54 times greater that of standard KDP and urea crystals respectively. (C) 2013 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.saa.2013.07.021

文献信息

• An expeditious one-pot synthesis of substituted phenylazetidin-2-ones in the presence of zeolite
  作者：Ramakanth Pagadala、Jyotsna S. Meshram、Himani N. Chopde、Venkateshwarlu Jetti、V. Udayini

  DOI：10.1002/jhet.604

  日期：2011.9

  In this study, one‐pot rapid and efficient series of phenylazetidin‐2‐ones were synthesized from N,N‐dimethylaminobenzaldehyde, different substituted aromatic amines and phenylacetyl chloride in the presence of zeolite catalyst under microwave irradiation. We also reported schiff bases (1a–j) by classical and conventional microwave technique. The titled compounds are evaluated for their antimicrobial

  在这项研究中，在微波辐射下，在沸石催化剂的存在下，由N，N-二甲基氨基苯甲醛，不同的取代芳香胺和苯基乙酰氯合成了一个单锅快速高效的一系列苯氮杂环丁烷-2-酮。我们还通过经典和常规微波技术报道了席夫碱（1a–j）。评价标题化合物的抗微生物特性。的活动是由于CO，C  N，2-氮杂环丁酮的联系。所有化合物均显示出可比的抗菌活性。J.杂环化​​学。（2011）。
• Hadjoudis, E., Molecular Crystals and Liquid Crystals (1969-1991), 1986, vol. 137, p. 17 - 28
  作者：Hadjoudis, E.

  DOI：——

  日期：——
• Synthesis, crystal growth and spectroscopic investigation of second order organic nonlinear optical single crystal: 2-Chloro-N-[4-(dimethylamino)benzylidene]aniline
  作者：R.K. Balachandar、S. Kalainathan

  DOI：10.1016/j.saa.2013.07.021

  日期：2013.12

  Organic nonlinear optical (NLO) crystal 2-chloro-N-14-(dimethylamino)benzylidene]aniline (2CI4DBA) was synthesized and grown by restricted slow evaporation technique at room temperature using acetone as solvent with good degree of transparency. The lattice parameters were determined and found to be noncentrosymmetric orthorhombic system by single crystal X-ray diffraction. The crystalline nature of the synthesized material was recorded by the powder X-ray diffraction pattern. Molecular structure of the grown crystal was investigated by 1H and 13C NMR and functional groups were identified by FTIR spectrum analysis. The optical absorbance of the grown crystal was ascertained by recording UV Visible spectrum. Thermal and physiochemical stability of the grown material was investigated by TG/DTA analysis. SHG efficiency was determined by Kurtz Perry Powder SHG technique and found to be 4.2 and 1.54 times greater that of standard KDP and urea crystals respectively. (C) 2013 Elsevier B.V. All rights reserved.