3'-hydroxy-4'-methyl-deoxybenzoin | 101093-45-2

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: 3'-hydroxy-4'-methyl-deoxybenzoin
• 英文别名: 3'-Hydroxy-4'-methyl-desoxybenzoin；2-(3-Hydroxy-4-methylphenyl)-1-phenylethanone；2-(3-hydroxy-4-methylphenyl)-1-phenylethanone
• CAS: 101093-45-2
• 化学式: C₁₅H₁₄O₂
• 分子量: 226.275
• InChiKey: VDFVOKUOWMJPIT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  17
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.13
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  6-acetoxy-6-methylcyclohexa-2,4-dienone 在 哌啶 、 磷酸 作用下， 生成 3'-hydroxy-4'-methyl-deoxybenzoin
  参考文献：
  名称：

  Ultrasonographic, Axial, and Peripheral Measurements in Female Patients with Benign Hypermobility Syndrome

  摘要：

  Twenty-five female Caucasians, aged 19-57 years, with the hypermobility syndrome had bone density measurements using established noninvasive techniques such as dual X-ray absorptiometry (DXA), single photon absorptiometry (SPA), heel ultrasound (US), and peripheral computed tomography (pQCT) acquisitions of the radius. As a group, comparisons of the different bone indices with the corresponding age-matched reference population resulted in normal z-scores for the arial densities, however, values for the volumetric total and cortical bone at the radius measured by pQCT were significantly lower than expected (P < 0.0001). Spinal and femoral bone density results were significant after correction for body mass index (BMI). This cross-sectional study shows that the benign hypermobility syndrome patients have lowered t-scores for data reflecting bone structure and bone strength as measured with US and the tomographic technique.

  DOI：

  10.1007/s00223001093

文献信息

• Ultrasonographic, Axial, and Peripheral Measurements in Female Patients with Benign Hypermobility Syndrome
  作者：J. Nijs、E. Van Essche、M. De Munck、J. Dequeker

  DOI：10.1007/s00223001093

  日期：2000.7

  Twenty-five female Caucasians, aged 19-57 years, with the hypermobility syndrome had bone density measurements using established noninvasive techniques such as dual X-ray absorptiometry (DXA), single photon absorptiometry (SPA), heel ultrasound (US), and peripheral computed tomography (pQCT) acquisitions of the radius. As a group, comparisons of the different bone indices with the corresponding age-matched reference population resulted in normal z-scores for the arial densities, however, values for the volumetric total and cortical bone at the radius measured by pQCT were significantly lower than expected (P < 0.0001). Spinal and femoral bone density results were significant after correction for body mass index (BMI). This cross-sectional study shows that the benign hypermobility syndrome patients have lowered t-scores for data reflecting bone structure and bone strength as measured with US and the tomographic technique.