2-tert-butoxybenzoxazole | 89114-28-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并恶唑类
• 英文名称: 2-tert-butoxybenzoxazole
• 英文别名: Benzoxazole, 2-(1,1-dimethylethoxy)-；2-[(2-methylpropan-2-yl)oxy]-1,3-benzoxazole
• CAS: 89114-28-3
• 化学式: C₁₁H₁₃NO₂
• 分子量: 191.23
• InChiKey: NOQCRQAVECHJIO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  35.3
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  叔丁醇 、 2-巯基苯并恶唑 在 sodium hydride 、 碘甲烷 作用下， 生成 2-tert-butoxybenzoxazole
  参考文献：
  名称：

  A new method for the preparation of 2-alkoxybenzoxazoles.

  摘要：

  一种从苯并噁唑-2-硫酮（II）合成2-烷氧基苯并噁唑（I）的单锅合成法得以实现。将在室温下用碘甲烷处理苯并噁唑-2-硫酮，然后在氢化钠存在下加入醇，可以得到I。该反应涉及中间体2-(甲硫基)苯并噁唑（IIIa），随后通过烷氧负离子取代甲硫基。讨论了该方法的普遍适用性。

  DOI：

  10.1248/cpb.31.3946

文献信息

• Inhibiting germination of clostridium perfringens spores to reduce necrotic enteritis
  申请人：The Board of Regents of the Nevada System of Higher Education on Behalf of the University of Nevada

  公开号：US10945996B2

  公开（公告）日：2021-03-16

  Provided herein are materials and methods useful for reducing, preventing, and/or inhibiting germination of C. perfringens spores, including methods for inhibiting C. perfringens germination to reduce necrotizing enteritis (NE, also referred to as necrotic enteritis) in animals. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

  本文提供了用于减少、预防和/或抑制C. perfringens孢子萌发的材料和方法，包括抑制C. perfringens萌发以减少动物坏死性肠炎（NE，也称为坏死性肠炎）的方法。本摘要旨在作为特定技术领域的扫描工具，供检索之用，并非对本发明的限制。
• YAMATO, MASATOSHI;TAKEUCHI, YASUO;HATTORI, KYOKO;HASHIGAKI, KUNIKO, CHEM. AND PHARM. BULL., 1983, 31, N 11, 3946-3950
  作者：YAMATO, MASATOSHI、TAKEUCHI, YASUO、HATTORI, KYOKO、HASHIGAKI, KUNIKO

  DOI：——

  日期：——
• Inhibiting Germination of Clostridium Perfringens Spores to Reduce Necrotic Enteritis
  申请人：Abel-Santos Ernesto

  公开号：US20180000793A1

  公开（公告）日：2018-01-04

  Provided herein are materials and methods useful for reducing, preventing, and/or inhibiting germination of C. perfringens spores, including methods for inhibiting C. perfringens germination to reduce necrotizing enteritis (NE, also referred to as necrotic enteritis) in animals. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
• US7297699B2
  申请人：——

  公开号：US7297699B2

  公开（公告）日：2007-11-20
• [EN] INHIBITING GERMINATION OF CLOSTRIDIUM PERFRINGENS SPORES TO REDUCE NECROTIC ENTERITIS<br/>[FR] INHIBITION DE LA GERMINATION DES SPORES DE CLOSTRIDIUM PERFRINGENS POUR RÉDUIRE L'ENTÉRITE NÉCROTIQUE
  申请人：ABEL-SANTOS ERNESTO

  公开号：WO2016127102A2

  公开（公告）日：2016-08-11

  Provided herein are materials and methods useful for reducing, preventing, and/or inhibiting germination of C. perfringens spores, including methods for inhibiting C.perfringens germination to reduce necrotizing enteritis (NE, also referred to as necrotic enteritis) in animals. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.