(25S)-26-[(β-D-glucopyranosyl)oxy]-22α-methoxyfurost-5-en-3β-yl O-α-L-rhamnopyranosyl-(1->2)-O-[O-β-D-glucopyranosyl-(1->4)-α-L-rhamnopyranosyl-(1->3)]-β-D-glucopyranoside | 290809-76-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: (25S)-26-[(β-D-glucopyranosyl)oxy]-22α-methoxyfurost-5-en-3β-yl O-α-L-rhamnopyranosyl-(1->2)-O-[O-β-D-glucopyranosyl-(1->4)-α-L-rhamnopyranosyl-(1->3)]-β-D-glucopyranoside
• 英文别名: (2S,3R,4R,5R,6S)-2-[(2R,3R,4S,5R,6R)-4-[(2S,3R,4S,5R,6S)-3,4-dihydroxy-6-methyl-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-6-(hydroxymethyl)-2-[[(1S,2S,4S,6R,7S,8R,9S,12S,13R,16S)-6-methoxy-7,9,13-trimethyl-6-[(3S)-3-methyl-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxybutyl]-5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-en-16-yl]oxy]oxan-3-yl]oxy-6-methyloxane-3,4,5-triol
• CAS: 290809-76-6
• 化学式: C₅₈H₉₆O₂₇
• 分子量: 1225.38
• InChiKey: SYSUVSWAEOKAPR-MZVWYRGJSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.8
• 重原子数：
  85
• 可旋转键数：
  18
• 环数：
  10.0
• sp3杂化的碳原子比例：
  0.97
• 拓扑面积：
  414
• 氢给体数：
  15
• 氢受体数：
  27

反应信息

• 作为反应物：
  描述：

  (25S)-26-[(β-D-glucopyranosyl)oxy]-22α-methoxyfurost-5-en-3β-yl O-α-L-rhamnopyranosyl-(1->2)-O-[O-β-D-glucopyranosyl-(1->4)-α-L-rhamnopyranosyl-(1->3)]-β-D-glucopyranoside 在 盐酸 作用下， 以 1,4-二氧六环 为溶剂， 反应 2.0h， 以3.0 mg的产率得到薯蓣皂素
  参考文献：
  名称：

  Steroidal and Pregnane Glycosides from the Rhizomes of Tacca chantrieri

  摘要：

  The rhizomes of Tacca chantrieri have been analyzed as part of a systematic study on saponin constituents of medicinal plants. This has resulted in the isolation of three new bisdesmosidic furostanol saponins (1-3), two new bisdesmosidic pseudofurostanol saponins (4, 5), and two new pregnane glycosides (6, 7). Their structures were determined on the basis of extensive spectroscopic studies and a few chemical transformations.

  DOI：

  10.1021/np020094l
• 作为产物：
  描述：

  (25S)-26-[(β-D-glucopyranosyl)oxy]-22α-methoxyfurost-5-en-3β-yl O-α-L-rhamnopyranosyl-(1->2)-O-[O-β-D-glucopyranosyl-(1->4)-α-L-rhamnopyranosyl-(1->3)]-6-O-acetyl-β-D-glucopyranoside 在 sodium methylate 作用下， 以 甲醇 为溶剂， 反应 1.0h， 以9.0 mg的产率得到(25S)-26-[(β-D-glucopyranosyl)oxy]-22α-methoxyfurost-5-en-3β-yl O-α-L-rhamnopyranosyl-(1->2)-O-[O-β-D-glucopyranosyl-(1->4)-α-L-rhamnopyranosyl-(1->3)]-β-D-glucopyranoside
  参考文献：
  名称：

  Steroidal and Pregnane Glycosides from the Rhizomes of Tacca chantrieri

  摘要：

  The rhizomes of Tacca chantrieri have been analyzed as part of a systematic study on saponin constituents of medicinal plants. This has resulted in the isolation of three new bisdesmosidic furostanol saponins (1-3), two new bisdesmosidic pseudofurostanol saponins (4, 5), and two new pregnane glycosides (6, 7). Their structures were determined on the basis of extensive spectroscopic studies and a few chemical transformations.

  DOI：

  10.1021/np020094l

文献信息

• Steroidal and Pregnane Glycosides from the Rhizomes of <i>Tacca </i><i>c</i><i>hantrieri</i>
  作者：Akihito Yokosuka、Yoshihiro Mimaki、Yutaka Sashida

  DOI：10.1021/np020094l

  日期：2002.9.1

  The rhizomes of Tacca chantrieri have been analyzed as part of a systematic study on saponin constituents of medicinal plants. This has resulted in the isolation of three new bisdesmosidic furostanol saponins (1-3), two new bisdesmosidic pseudofurostanol saponins (4, 5), and two new pregnane glycosides (6, 7). Their structures were determined on the basis of extensive spectroscopic studies and a few chemical transformations.