(vinylsulfonyl)cyclohexane | 21961-10-4

• 分子结构分类: 有机化合物 - 有机硫化合物 - 磺酰类
• 英文名称: (vinylsulfonyl)cyclohexane
• 英文别名: (Ethenesulfonyl)cyclohexane；ethenylsulfonylcyclohexane
• CAS: 21961-10-4
• 化学式: C₈H₁₄O₂S
• 分子量: 174.264
• InChiKey: JHGHTBSOZYDUJC-UHFFFAOYSA-N

物化性质

• 沸点：
  320.1±9.0 °C(Predicted)
• 密度：
  1.10±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  42.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  (vinylsulfonyl)cyclohexane 、 苯次磺酰氯 以 溶剂黄146 为溶剂， 生成 2-CHLORO-1-(CYCLOHEXYLSULFONYL)ETHYL PHENYL SULFIDE
  参考文献：
  名称：

  Aryl (1-arylsulfonyl) vinyl sulfones

  摘要：

  一种具有一般式##STR1##的微生物灭活剂，其中R是卤甲基基团或亚甲基基团；W是环己基、苯基或对位或间位取代的苯基，其中取代基为C.sub.1-C.sub.4烷基、卤素或硝基；X和Y是氢、C.sub.1-C.sub.4烷基、卤素或硝基；但当R为卤甲基时，n为1，当R为亚甲基时，n为0。

  公开号：

  US04335142A1
• 作为产物：
  描述：

  cyclohexyl vinyl sulfide 在 过氧乙酸 作用下， 以 乙醚 为溶剂， 生成 (vinylsulfonyl)cyclohexane
  参考文献：
  名称：

  A new method of synthesizing ?,?-unsaturated sulfides

  摘要：

  DOI：

  10.1007/bf00904043

文献信息

• Diastereoselective Monofluorocyclopropanation Using Fluoromethylsulfonium Salts
  作者：Renate Melngaile、Arturs Sperga、Kim K. Baldridge、Janis Veliks

  DOI：10.1021/acs.orglett.9b02867

  日期：2019.9.6

  Diarylfluoromethylsulfonium salts, alternatives to freons or advanced fluorinated building blocks, are bench stable and easy-to-use sources of direct fluoromethylene (:CHF) transfer to alkenes. These salts enabled development of a trans-selective monofluorinated Johnson-Corey-Chaykovsky reaction with vinyl sulfones or vinyl sulfonamides to access synthetically challenging monofluorocyclopropane scaffolds

  二芳基氟甲基s盐是氟利昂或高级氟化构件的替代品，是直接将氟亚甲基（：CHF）转移至烯烃的稳定且易于使用的来源。这些盐使得能够开发与乙烯基砜或乙烯基磺酰胺的反式单氟化Johnson-Corey-Chaykovsky反应，从而获得具有挑战性的单氟环丙烷支架。所描述的方法提供了快速进入单氟化环丙烷结构单元的途径，并具有进一步的功能化机会，可以非对映选择性地递送更复杂的合成靶标。
• MICRO/NANO MATERIALS, PRODUCTS OBTAINED BY COVALENTLY MODIFYING SURFACE OF MICRO/NANO MATERIALS WITH HYDROPHILIC MATERIALS, AND METHOD FOR MAKING SAME
  申请人：CHONGQING BOLANYING (BLY) BIOTECHNOLOGY CO., LTD.

  公开号：US20190077746A1

  公开（公告）日：2019-03-14

  Micro-nano materials, products obtained by covalently modifying the surfaces of micro/nano materials with hydrophilic materials, and methods for making the same. The micro/nano materials on the surfaces have carboxyl groups or/and pro-carboxyl groups which are converted into their active esters. The products are covalently modified by forming amide bonds between the active esters on the surfaces and the modification agents; where the modification agents are hydrophilic compounds and/or hydrophilic polymers bearing primary and/or secondary aliphatic amines. Monomers bearing carboxyl groups and/or pro-carboxyl groups are used to produce an adequate number of carboxyl groups and/or pro-carboxyl groups on the surface of a polymer material to be modified. The carboxyl groups and/or pro-carboxyl groups are converted into active esters. A reasonably-sized modification agent bearing primary and/or secondary amines, zwitterions and hydrophilic linear spacer arms is used to form amide bonds and obtain a covalently modified surface layer.

  微纳米材料，通过用亲水材料共价修饰微/纳米材料表面获得的产品，以及制备这些产品的方法。表面上的微/纳米材料具有羧基或/和前羧基，这些羧基或前羧基被转化为它们的活性酯。通过在表面上的活性酯和修饰剂之间形成酰胺键，共价修饰的产品；其中修饰剂是带有一次和/或二次脂肪胺基的亲水化合物和/或亲水性聚合物。使用带有羧基和/或前羧基的单体来产生足够数量的羧基和/或前羧基，以便在待修饰的聚合物材料表面上形成。将羧基和/或前羧基转化为活性酯。使用合理大小的带有一次和/或二次胺基、带有带电离子和亲水性线性间隔臂的修饰剂来形成酰胺键，并获得共价修饰的表面层。
• Quinoxalin-2-one derivatives, compositions which protect useful plants and comprise these derivatives, and processes for their preparation and their use
  申请人：Schaper Wolfgang

  公开号：US20050256000A1

  公开（公告）日：2005-11-17

  Compounds of the formula (I) and salts thereof in which X is O or S; (Y) n =n substituents Y, n is 0, 1, 2, 3 or 4, R 1 is H, OH, NH 2 , (C 1 -C 4 )-alkylamino, di-[(C 1 -C 4 )-alkyl]amino or optionally substituted (C 1 -C 10 )-alkyl, (C 3 -C 10 )-alkenyl, (C 3 -C 10 )-alkynyl or (C 1 -C 10 )-alkoxy, (C 3 -C 10 )-cycloalkyl, (C 4 -C 10 )-cycloalkenyl, aryl or heterocyclyl, R 2 is H or optionally substituted (C 1 -C 10 )-alkyl, (C 3 -C 10 )-alkenyl, (C 3 -C 10 )-alkynyl, (C 3 -C 10 )-cycloalkyl, (C 4 -C 10 )-cycloalkenyl, aryl or heterocyclyl, where the radicals Y are as defined in claim 1 are suitable for use as safeners for crop plants or useful plants against the phytotoxic actions of agrochemicals such as pesticides in these plants.

  该式(I)的化合物及其盐，其中X为O或S；(Y)n=n取代基Y，n为0、1、2、3或4，R1为H、OH、NH2、(C1-C4)-烷基氨基、二-[(C1-C4)-烷基]氨基或可选择取代的(C1-C10)-烷基、(C3-C10)-烯基、(C3-C10)-炔基或(C1-C10)-烷氧基、(C3-C10)-环烷基、(C4-C10)-环烯基、芳基或杂环烷基，R2为H或可选择取代的(C1-C10)-烷基、(C3-C10)-烯基、(C3-C10)-炔基、(C3-C10)-环烷基、(C4-C10)-环烯基、芳基或杂环烷基，其中所述的基Y如权利要求1所定义的适用于作为作物植物或有用植物的安全剂，用于抵抗这些植物中农药等农药的植物毒性作用。
• Fused benzo compounds containing a nitrogen heterocycle for the
  申请人：H. Lundbeck A/S

  公开号：US05753661A1

  公开（公告）日：1998-05-19

  Fused benzo compounds of formula I are provided, wherein A is a 2 to 6 membered hydrocarbon spacer group, B is a polar divalent group selected from a group (a); U is C, N or CH; X is a divalent 3-4 membered chain optionally comprising one or more heteroatoms; R.sup.1 is an aliphatic hydrocarbon group, arylalkyl or diphenylalkyl; R.sup.2 and R.sup.3 are hydrogen or alkyl or together form an ethylene or propylene bridge; R.sup.4, R.sup.5 and R.sup.6 are hydrogen or substituents; R.sup.7 and R.sup.8 are hydrogen or substituents including --COOR.sup.9 and --CONR.sup.10 R.sup.11 ; are 5-HT.sub.1A receptor ligands useful in the treatment of CNS disorders. Pharmaceutical compositions comprising the compounds and their use for the manufacture of a pharmaceutical preparation are also provided.

  提供了式I的融合苯并化合物，其中A是一个2到6个成员的碳氢化合物间隔基团，B是从组（a）中选择的极性二价基团；U是C、N或CH；X是一个二价的3-4个成员的链，可选地包括一个或多个杂原子；R.sup.1是一个脂肪烃基、芳基烷基或二苯基烷基；R.sup.2和R.sup.3是氢或烷基，或者一起形成一个乙烯或丙烯桥；R.sup.4、R.sup.5和R.sup.6是氢或取代基；R.sup.7和R.sup.8是氢或取代基，包括--COOR.sup.9和--CONR.sup.10 R.sup.11；是用于治疗中枢神经系统疾病的5-HT.sub.1A受体配体。还提供了包含这些化合物的药物组合物以及它们用于制备药物制剂的用途。
• Heterocyclic amides, a process for their preparation, compositions comprising them and their use
  申请人：——

  公开号：US20040006047A1

  公开（公告）日：2004-01-08

  What is described are amides of the formula (I) and salts thereof, 1 where the symbols and indices are as defined below: X is CH or N; Y is O or S; n is 0 or 1; R 1 is (C 1 -C 4 )-haloalkyl; R 2 , R 3 independently of one another are hydrogen, (C 1 -C 4 )-alkyl, (C 1 -C 4 )-haloalkyl or halogen, R 4 is hydrogen, (C 1 -C 10 )-alkyl, (C 3 -C 10 )-cycloalkyl, (C 3 -C 10 )-alkenyl or (C 3 -C 10 )-alkynyl, where in the alkyl, cycloalkyl, alkenyl or alkynyl groups mentioned up to three hydrogen atoms may be replaced by halogen, in the case of fluorine also up to the maximum number; R 5 is an aliphatic heterocycle which contains at least one oxygen, sulfur, nitrogen and/or silicon ring atom, which is unsubstituted or substituted by one to six monovalent groups and which may be part of a spirocyclic, fused or bicyclic ring system. These compounds can be used for controlling pests.

  描述的是化合物(I)及其盐的酰胺，其中符号和指数定义如下：X为CH或N；Y为O或S；n为0或1；R1为(C1-C4)-卤代烷基；R2，R3分别为氢，(C1-C4)-烷基，(C1-C4)-卤代烷基或卤素；R4为氢，(C1-C10)-烷基，(C3-C10)-环烷基，(C3-C10)-烯基或(C3-C10)-炔基，其中在所述烷基，环烷基，烯基或炔基中最多三个氢原子可被卤素取代，对于氟也可达到最大数量；R5是含有至少一个氧，硫，氮和/或硅环原子的脂肪杂环，该环原子未取代或被一到六个一价基团取代，并且可能是螺环，融合环或双环系统的一部分。这些化合物可用于控制害虫。