2,8,24,29-Tetraoxa-20,33-diazapentacyclo[33.8.0.09,18.012,17.036,41]tritetraconta-1(35),9(18),10,12,14,16,36,38,40,42-decaene | 1314774-05-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 2,8,24,29-Tetraoxa-20,33-diazapentacyclo[33.8.0.09,18.012,17.036,41]tritetraconta-1(35),9(18),10,12,14,16,36,38,40,42-decaene
• 英文别名: 2,8,24,29-tetraoxa-20,33-diazapentacyclo[33.8.0.09,18.012,17.036,41]tritetraconta-1(35),9(18),10,12,14,16,36,38,40,42-decaene
• CAS: 1314774-05-4
• 化学式: C₃₇H₄₈N₂O₄
• 分子量: 584.799
• InChiKey: QAWICJWTAFMDPR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.8
• 重原子数：
  43
• 可旋转键数：
  0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  61
• 氢给体数：
  2
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  O,O'-(1,5-pentanediyl)bis(1-formylnaphthol) 在 sodium tetrahydroborate 、 乙醇 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 5.0h， 生成 2,8,24,29-Tetraoxa-20,33-diazapentacyclo[33.8.0.09,18.012,17.036,41]tritetraconta-1(35),9(18),10,12,14,16,36,38,40,42-decaene
  参考文献：
  名称：

  Efficient synthesis of naphthodiazacrown ethers

  摘要：

  A benign and efficient synthesis of naphthodiazacrown ethers has been described. Reaction of simple dialdehyde precursor with alpha,omega-diamines followed by sodium borohydride reduction leads to 16-27 membered naphthodiazacrown ethers in 80-90% yields. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2011.05.057

文献信息

• Efficient synthesis of naphthodiazacrown ethers
  作者：Pallavi Singh、Rajiv K. Verma、Maya Shankar Singh

  DOI：10.1016/j.tetlet.2011.05.057

  日期：2011.7

  A benign and efficient synthesis of naphthodiazacrown ethers has been described. Reaction of simple dialdehyde precursor with alpha,omega-diamines followed by sodium borohydride reduction leads to 16-27 membered naphthodiazacrown ethers in 80-90% yields. (C) 2011 Elsevier Ltd. All rights reserved.