2-(2,2,7-trifluoro-3-oxo-4-propargyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-4,5,6,7-tetrahydro-1H-isoindole-1,3(2H)-dione | 1300118-96-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并恶嗪类
• 英文名称: 2-(2,2,7-trifluoro-3-oxo-4-propargyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-4,5,6,7-tetrahydro-1H-isoindole-1,3(2H)-dione
• 英文别名: 2-(2,2,7-trifluoro-3-oxo-4-prop-2-ynyl-3,4-dihydro-2H-benzo[1,4]oxazin-6-yl)-4,5,6,7-tetrahydro-isoindole-1,3-dione；2-(2,2,7-trifluoro-3-oxo-4-prop-2-ynyl-1,4-benzoxazin-6-yl)-4,5,6,7-tetrahydroisoindole-1,3-dione
• CAS: 1300118-96-0
• 化学式: C₁₉H₁₃F₃N₂O₄
• 分子量: 390.318
• InChiKey: IYMFSFAEKKEILH-UHFFFAOYSA-N

物化性质

• 沸点：
  605.8±55.0 °C(Predicted)
• 密度：
  1.57±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  28
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.32
• 拓扑面积：
  66.9
• 氢给体数：
  0
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  2-(7-fluoro-2,2-dichloro-3-oxo-4-propargyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-4,5,6,7-tetrahydro-1H-isoindole-1,3(2H)-dione 在 氟化氢吡啶 作用下， 反应 2.0h， 以80%的产率得到2-(2,2,7-trifluoro-3-oxo-4-propargyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-4,5,6,7-tetrahydro-1H-isoindole-1,3(2H)-dione
  参考文献：
  名称：

  2,2,7-三氟-2H-1,4-苯并噁嗪-3(4H)-酮类化合 物的制备方法

  摘要：

  本发明公开了一种2,2,7-三氟-2H-1,4-苯并噁嗪-3(4H)-酮类化合物的制备方法，该方法包括：（1）将7-氟-2H-1,4-苯并噁嗪-3(4H)-酮类化合物与氯化试剂在第一反应介质中进行氯化反应，生成2,2-二氯-7-氟-2H-1,4-苯并噁嗪-3(4H)-酮类化合物；（2）将2,2-二氯-7-氟-2H-1,4-苯并噁嗪-3(4H)-酮类化合物与氟化试剂进行氯-氟交换反应。本发明提供的方法可以获得较高的产品收率，由于使用的原料安全、易得，反应过程中也不会产生有安全隐患的中间产物，克服了现有工艺中存在的原料价格昂贵、安全性差以及反应过程中产生有安全隐患的中间产物的不足。

  公开号：

  CN103951632B

文献信息

• [EN] PYRIDOTHIAZINES HAVING HERBICIDAL ACTION<br/>[FR] PYRIDOTHIAZINES À ACTION HERBICIDE
  申请人：BASF SE

  公开号：WO2011117152A1

  公开（公告）日：2011-09-29

  Substituted pyridines of the formula I in which the variables are defined according to the description, processes and intermediates for preparing the compounds of the formula I and their N-oxides, their agriculturally suitable salts, compositions comprising them and their use as herbicides, and also methods for controlling unwanted vegetation.

  将公式I中定义的变量的吡啶替代物，用于制备公式I化合物及其N-氧化物的过程和中间体，它们的农业适用盐，包含它们的组合物以及它们作为除草剂的用途，以及控制不受欢迎植被的方法。
• [EN] USE OF SUBSTITUTED OXADIAZOLES FOR COMBATING PHYTOPATHOGENIC FUNGI<br/>[FR] UTILISATION D'OXADIAZOLES SUBSTITUÉS POUR COMBATTRE DES CHAMPIGNONS PHYTOPATHOGÈNES
  申请人：BASF SE

  公开号：WO2017076739A1

  公开（公告）日：2017-05-11

  The present invention relates to novel oxadiazoles of the formula I, or the N-oxides and/or their agriculturally useful salts and to their use for controlling phytopathogenic fungi, or to a method for combating phytopathogenic harmful fungi, which process comprises treating the fungi or the materials, plants, the soil or seeds to be protected against fungal attack, with an effective amount of at least one compound of the formula I, or an N-oxide, or an agriculturally acceptable salt thereof; the present invention also relates to mixtures comprising at least one such compound of the formula I and at least one further pesticidally active substance selected from the group consisting of herbicides, safeners, fungicides, insecticides, and plant growth regulators; and to agrochemical compositions comprising at least one such compound of the formula I and to agrochemical compositions further comprising seeds. Formula (I).

  本发明涉及式I的新型噁二唑化合物，或其N-氧化物和/或其在农业上有用的盐，以及它们用于控制植物病原真菌，或用于对抗植物病原有害真菌的方法，该方法包括用式I的至少一种化合物、N-氧化物或其农业上可接受的盐的有效量处理真菌或需要受到保护免受真菌侵害的材料、植物、土壤或种子；本发明还涉及包含至少一种式I的化合物和从除草剂、安全剂、杀菌剂、杀虫剂和植物生长调节剂组成的至少一种进一步具有杀虫活性的物质的混合物；以及包含至少一种式I的化合物的农药组合物，以及进一步包含种子的农药组合物。Formula (I).
• [EN] BENZAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES II<br/>[FR] COMPOSÉS DE BENZAMIDE ET LEUR UTILISATION EN TANT QU'HERBICIDES II
  申请人：BASF SE

  公开号：WO2018219936A1

  公开（公告）日：2018-12-06

  The invention relates to benzamides of formula (I), wherein Q is Q1 or Q2 or Q3 or Q4, and their use as herbicides. In said formula (I), R2 is R2cR2dNC(O)NR2n-Z2, R5 is hydrogen, R1, R3, R4 and R6 represent groups such as hydrogen, halogen or organic groups such as alkyl or phenyl.The invention further refers to a composition comprising such compound and to the use thereof for controlling unwanted vegetation.

  该发明涉及式(I)的苯甲酰胺，其中Q是Q1或Q2或Q3或Q4，并且它们作为除草剂的用途。在所述的式(I)中，R2是R2cR2dNC(O)NR2n-Z2，R5是氢，R1、R3、R4和R6代表氢、卤素或有机基团，如烷基或苯基。该发明还涉及包含这种化合物的组合物以及将其用于控制不受欢迎的植被的用途。
• [EN] HERBICIDAL PYRIMIDINE COMPOUNDS<br/>[FR] COMPOSÉS HERBICIDES DE PYRIMIDINE
  申请人：BASF SE

  公开号：WO2018019574A1

  公开（公告）日：2018-02-01

  The present invention relates to the pyrimidine compounds of formula (I), or their agriculturally acceptable salts or derivatives as herbicides, wherein the variables are defined according to the description, use of pyrimidine compounds of formula (I) as herbicide, compositions comprising them and their use as herbicides, i.e. for controlling harmful plants, and also a method for controlling unwanted vegetation which comprises allowing a herbicidal effective amount of at least one pyrimidine compounds of the formula (I) to act on plants, their seed and/or their habitat.

  本发明涉及式(I)的嘧啶化合物，或其农业上可接受的盐或衍生物作为除草剂，其中变量根据描述定义，使用式(I)的嘧啶化合物作为除草剂，包含它们的组合物及其用作除草剂，即用于控制有害植物，以及一种控制不需要的植被的方法，该方法包括使至少一种式(I)的嘧啶化合物以除草有效量作用于植物、其种子和/或其栖息地。
• [EN] SUBSTITUTED PYRIDAZINES HAVING HERBICIDAL ACTION<br/>[FR] PYRIDAZINES SUBSTITUÉES À ACTION HERBICIDE
  申请人：BASF SE

  公开号：WO2011117211A1

  公开（公告）日：2011-09-29

  Substituted pyridazines of the formula (I) in which the variables are defined according to the description, processes and intermediates for preparing the compounds of the formula (I) and their N-oxides, their agriculturally suitable salts, compositions comprising them and their use as herbicides, and also methods for controlling unwanted vegetation.

  根据描述定义的变量，将公式（I）的吡啶并嗪进行替代，制备公式（I）化合物及其N-氧化物的过程和中间体，它们的农业适用盐，包含它们的组合物以及它们作为除草剂的用途，以及控制不受欢迎植被的方法。