(β-methoxy-isopropyl)-dimethyl-amine | 44643-00-7

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: (β-methoxy-isopropyl)-dimethyl-amine
• 英文别名: (β-Methoxy-isopropyl)-dimethyl-amin；2-Dimethylamino-1-methoxy-propan；Dimethyl-(β-methoxy-isopropyl)-amin；1-methoxy-N,N-dimethylpropan-2-amine
• CAS: 44643-00-7
• 化学式: C₆H₁₅NO
• 分子量: 117.191
• InChiKey: DRVYWHXAHNLFRV-UHFFFAOYSA-N

物化性质

• 沸点：
  115.5±13.0 °C(Predicted)
• 密度：
  0.827±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  8
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  12.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  sodium methylate 、 N,N-二甲氨基-2-氯丙烷盐酸盐 在 甲醇 作用下， 生成 (β-methoxy-isopropyl)-dimethyl-amine 、 (S)-(-)-2-Methoxy-N,N'-dimethyl-propylamin
  参考文献：
  名称：

  The Formation of Carbon to Metal σ Complexes between Palladium(II) Chloride and Allylic Amines

  摘要：

  DOI：

  10.1021/ja00978a021

文献信息

• [EN] HETEROAROMATIC AHR INHIBITOR<br/>[FR] INHIBITEUR D'AHR HÉTÉROAROMATIQUE<br/>[ZH] 杂芳环类AhR抑制剂
  申请人：SHANDONG XUANZHU PHARMA CO LTD

  公开号：WO2022078356A1

  公开（公告）日：2022-04-21

  本发明属于医药技术领域，具体涉及一类杂芳环类AhR抑制剂化合物、其药学上可接受的盐或其立体异构体，含有所述化合物、其药学上可接受的盐或其立体异构体的药物组合物及制剂，制备所述化合物、其药学上可接受的盐或其立体异构体的方法，以及所述化合物、其药学上可接受的盐或其立体异构体的用途。
• Novel 2-Cyano-3(Halo)Alkoxy-Benzenesulfonamide Compounds for Combating Animal Pests
  申请人：von Deyn Wolfgang

  公开号：US20080063678A1

  公开（公告）日：2008-03-13

  The invention relates to 2-cyano-3-(halo)alkoxy-benzenesulfonamide compounds I where the variables Alk and R 1 to R 5 are as defined in claim 1, and/or to their agriculturally useful salts. Moreover, the present invention relates to the use of compounds I and/or their salts for combating animal pests; agricultural compositions comprising such an amount of at least one compound of the general formula I and/or at least one agriculturally useful salt of I and at least one inert liquid and/or solid agronomically acceptable carrier that it has a pesticidal action and, if desired, at least one surfactant; and a method of combating animal pests which comprises contacting the animal pests, their habit, breeding ground, food supply, plant, seed, soil, area, material or environment in which the animal pests are growing or may grow, or the materials, plants, seeds, soils, surfaces or spaces to be protected from animal attack or infestation with a pesticidally effective amount of at least one2-cyano-3-(halo)alkoxy-benzenesulfonamide compound of the formula I and/or at least one agriculturally acceptable salt thereof. a method for the for the protection of seeds from soil insects and of the resulting plant's roots and shoots from soil and foliar insects comprising contacting the seeds before sowing and/or after pregermination with a 2-cyano-3-(halo)alkoxy-benzenesulfonamide compound of the general formula I

  本发明涉及2-氰基-3-(卤)烷氧基苯磺酰胺化合物I，其中变量Alk和R1至R5如权利要求1所定义，以及/或其在农业上有用的盐。此外，本发明还涉及使用化合物I和/或其盐来对抗动物害虫；包含至少一种通式I化合物和/或至少一种I的农业有用盐及至少一种惰性液体和/或固体农业上可接受的载体的农业组合物，其具有杀虫作用，如有需要，还包括至少一种表面活性剂；以及一种对抗动物害虫的方法，其中将至少一种2-氰基-3-(卤)烷氧基苯磺酰胺化合物I的杀虫有效量与动物害虫、它们的栖息地、繁殖地、食物供应、植物、种子、土壤、区域、材料或环境接触，或者接触需要保护免受动物攻击或侵害的材料、植物、种子、土壤、表面或空间。本发明还涉及一种保护种子免受土壤昆虫和由此产生的植物根和茎免受土壤和叶面昆虫的方法，其中在播种前和/或发芽前将种子与通式I的2-氰基-3-(卤)烷氧基苯磺酰胺化合物接触。
• NOVEL PYRIMIDINE DERIVATIVES 698
  申请人：Ashton Susan Elizabeth

  公开号：US20080242663A1

  公开（公告）日：2008-10-02

  The invention concerns compounds of Formula I, or a pharmaceutically acceptable salt thereof, where R 1 , n, R 2 , R 3 , and R 4 are as defined in the description. The present invention also relates to processes for the preparation of such compounds, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use as an antiproliferative agent in the prevention or treatment of tumours or other proliferative conditions which are sensitive to the inhibition of EphB4 kinases.

  本发明涉及公式I的化合物或其药学上可接受的盐，其中R1、n、R2、R3和R4如描述中所定义。本发明还涉及制备这种化合物的方法、包含它们的药物组合物以及它们在制造用于作为抗增殖剂用于预防或治疗对EphB4激酶抑制敏感的肿瘤或其他增殖性疾病的药物的用途。
• NOVEL 2-CYANO-3(HALO)ALKOXY-BENZENESULFONAMIDE COMPOUNDS FOR COMBATING ANIMAL PESTS
  申请人：Deyn Wolfgang von

  公开号：US20080306297A1

  公开（公告）日：2008-12-11

  Novel 2-cyano-3-(halo)alkoxy-benzenesulfonamide compounds for combating animal pests The invention relates to 2-cyano-3-(halo)alkoxy-benzenesulfonamide compounds I where the variables Alk and R 1 to R 5 are as defined in claim 1 , and/or to their agriculturally useful salts. Moreover, the present invention relates to the use of compounds I and/or their salts for combating animal pests; agricultural compositions comprising such an amount of at least one compound of the general formula I and/or at least one agriculturally useful salt of I and at least one inert liquid and/or solid agronomically acceptable carrier that it has a pesticidal action and, if desired, at least one surfactant; and a method of combating animal pests which comprises contacting the animal pests, their habit, breeding ground, food supply, plant, seed, soil, area, material or environment in which the animal pests are growing or may grow, or the materials, plants, seeds, soils, surfaces or spaces to be protected from animal attack or infestation with a pesticidally effective amount of at least one 2-cyano-3-(halo)alkoxy-benzenesulfonamide compound of the formula I and/or at least one agriculturally acceptable salt thereof. a method for the for the protection of seeds from soil insects and of the resulting plant's roots and shoots from soil and foliar insects comprising contacting the seeds before sowing and/or after pregermination with a 2-cyano-3-(halo)alkoxybenzenesulfonamide compound of the general formula I

  本发明涉及2-氰基-3-(卤代)烷氧基苯磺酰胺化合物I，其中变量Alk和R1至R5如权利要求1所定义，和/或其在农业上有用的盐。此外，本发明还涉及使用化合物I和/或其盐来对抗动物害虫的方法；包括至少一种通式I化合物和/或至少一种I的农业上有用的盐以及至少一种惰性液体和/或固体农业上可接受的载体的农业组合物，以产生杀虫作用，如果需要，还包括至少一种表面活性剂；以及一种对抗动物害虫的方法，其中将至少一种2-氰基-3-(卤代)烷氧基苯磺酰胺化合物I或其农业上可接受的盐以杀虫有效量接触动物害虫、它们的栖息地、繁殖地、食物供应、植物、种子、土壤、区域、材料或动物害虫生长或可能生长的环境以及需要保护免受动物攻击或侵染的材料、植物、种子、土壤、表面或空间。还涉及一种使用2-氰基-3-(卤代)烷氧基苯磺酰胺通式I化合物的方法，用于保护种子免受土壤昆虫和由此产生的植物根和茎免受土壤和叶面昆虫的侵害，在播种前和/或发芽前将种子与通式I的2-氰基-3-(卤代)烷氧基苯磺酰胺化合物接触。
• AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT EMPLOYING THE SAME
  申请人：IDEMITSU KOSAN CO., LTD.

  公开号：EP1864965A1

  公开（公告）日：2007-12-12

  An aromatic amine derivative having a specific structure having m-terphenyl group and an organic electroluminescence device comprising a cathode, an anode and an organic thin film layer which is disposed between the cathode and the anode and comprises at least one layer comprising at least a light emitting layer, wherein at least one layer in the organic thin film layer comprises the aromatic amine derivative singly or as a component of a mixture. The organic electroluminescence device has a long life.

  一种具有特定结构、带有间三联苯基团的芳香族胺衍生物，以及一种有机电致发光器件，该器件包括一个阴极、一个阳极和一个有机薄膜层，该有机薄膜层位于阴极和阳极之间，并包括至少一层发光层，其中有机薄膜层中的至少一层包括单个或作为混合物成分的芳香族胺衍生物。该有机电致发光装置具有较长的使用寿命。