3,6,8-三溴-2-甲基咪唑并[1,2-a]吡啶 | 306280-28-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 咪唑并吡啶类
• 中文名称: 3,6,8-三溴-2-甲基咪唑并[1,2-a]吡啶
• 英文名称: 3,6,8-tribromo-2-methylimidazo[1,2-a]pyridine
• CAS: 306280-28-4
• 化学式: C₈H₅Br₃N₂
• 分子量: 368.853
• InChiKey: CRSIRQVFBIWHQR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  13
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  17.3
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  在 双氧水 作用下， 反应 72.0h， 生成 3,6,8-三溴-2-甲基咪唑并[1,2-a]吡啶
  参考文献：
  名称：

  Oxidative bromination of imidazoheterocycle bromohydrates*

  摘要：

  The behavior of imidazo[1,2-a]pyridinium, imidazo[1,2-a]pyrimidinium, and imidazo[2,1-b]thiazolium bromides derivatives in oxidative bromination reactions has been studied. It has been established that reaction products structures and their yields depend on the properties of the substituents in the bicycle and the oxidant concentration.

  DOI：

  10.1007/s10593-012-0903-8

文献信息

• Oxidative bromination of imidazoheterocycle bromohydrates*
  作者：N. V. Kovalenko、A. Yu. Cherepakha、G. P. Kutrov、O. V. Shishkin、S. V. Shishkina

  DOI：10.1007/s10593-012-0903-8

  日期：2012.1

  The behavior of imidazo[1,2-a]pyridinium, imidazo[1,2-a]pyrimidinium, and imidazo[2,1-b]thiazolium bromides derivatives in oxidative bromination reactions has been studied. It has been established that reaction products structures and their yields depend on the properties of the substituents in the bicycle and the oxidant concentration.