Studies on the chemistry of thienoannelated<i>o,n</i>- and<i>s,n-</i>containing heterocycles.<b>16</b>. Synthesis of some thieno[1,4]thiazine derivatives with potential calcium antagonistic activity
作者:Thomas Erker
DOI:10.1002/jhet.5570350651
日期:1998.11
Substituted thieno[1,4]thiazine derivatives have been synthesized. They are thienoanalogues of compound 3 [2], a potent cerebral protectant and calcium antagonist. Research activities concentrate on the preparation of structurally modified compounds of 3 to minimize its undesirable symptoms.
已经合成了取代的噻吩并[1,4]噻嗪衍生物。它们是有效的脑保护剂和钙拮抗剂的化合物3 [2]的硫脲类化合物。研究活动集中在结构3的化合物的制备上,以最大程度地减少其不良症状。