2-ethyl-4-methyl-resorcinol | 412018-53-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 2-ethyl-4-methyl-resorcinol
• 英文别名: 2.4-Dihydroxy-1-methyl-3-aethyl-benzol；2-Aethyl-4-methyl-resorcin；Methylethylresorcin；2-ethyl-4-methylbenzene-1,3-diol
• CAS: 412018-53-2
• 化学式: C₉H₁₂O₂
• 分子量: 152.193
• InChiKey: DSYHFOPTZRKGJP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-ethyl-4-methyl-resorcinol 在 三氯化铝 、 硝基苯 作用下， 生成 7-ethyl-6-hydroxy-5-methyl-benzofuran-2,3-dione
  参考文献：
  名称：

  Citrinin Studies. Hydroxy- and Methoxy-phenylglyoxylic Acids¹

  摘要：

  DOI：

  10.1021/ja01163a017
• 作为产物：
  描述：

  3-acetyl-2,4-dihydroxybenzalodehyde 在 盐酸 、 amalgamated zinc 作用下， 生成 2-ethyl-4-methyl-resorcinol
  参考文献：
  名称：

  202. γ取代的间苯二酚核。第四部分 与多羟基苯乙酮的Gattermann反应

  摘要：

  DOI：

  10.1039/jr9390000949

文献信息

• MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME
  申请人：TABATA Masayoshi

  公开号：US20110224343A1

  公开（公告）日：2011-09-15

  The present invention provides a modifier for aromatic polyesters which enhances the melt fluidity of aromatic polyesters without a significant decrease in the heat resistance of the aromatic polyesters, and an aromatic polyester resin composition including the modifier for aromatic polyesters. The present invention relates to a modifier for aromatic polyesters comprising polyhydric phenol residues and residues of aromatic polycarboxylic acid, acid halide or acid anhydride thereof, and the modifier comprises a material having a structure composed of a first residue selected from the group consisting of divalent residues represented by Formula (I): —Ar—W 1 x —Ar— and by Formula (II): —Ar—, the first residues being bonded to two identical or different second residues selected from the group consisting of monovalent residues represented by Formula (III): and monovalent residues represented by Formula (IV): —O—C(O)—R 7 —.

  本发明提供了一种用于芳香族聚酯的改性剂，可以增强芳香族聚酯的熔融流动性，而不明显降低芳香族聚酯的耐热性，以及包括该改性剂的芳香族聚酯树脂组合物。本发明涉及一种用于芳香族聚酯的改性剂，包括多羟基酚残基和芳香族多羧酸、酸卤或其酸酐残基，该改性剂包括具有以下结构的材料：第一残基，选择自由式(I)所代表的二价残基：—Ar—W1x—Ar—和自由式(II)所代表的：—Ar—，第一残基与选择自由式(III)所代表的单价残基：和自由式(IV)所代表的单价残基：—O—C(O)—R7—的两个相同或不同的第二残基结合。
• Differential effects of UTP and ATP on ion transport in porcine tracheal epithelium
  作者：S K Inglis、R E Olver、S M Wilson

  DOI：10.1038/sj.bjp.0703324

  日期：2000.5

  Isolated segments of porcine tracheal epithelium were mounted in Ussing chambers, current required to maintain transepithelial potential difference at 0 mV (short circuit current, ISC) was monitored and effects of nucleotides upon ISC were studied. Mucosal UTP (100 μM) evoked a transient rise in ISC that was followed by a sustained fall below basal ISC maintained for 30 min. Mucosal ATP (100 μM) also stimulated a transient rise in ISC but in contrast to UTP did not inhibit basal ISC. Submucosal UTP and ATP both transiently increased ISC. UTP‐prestimulated epithelia were refractory to ATP but prestimulation with ATP did not abolish the response to UTP. The epithelia thus appear to express two populations of apical receptors allowing nucleotides to modulate ISC. The UTP‐induced rise was reduced by pretreatment with either bumetanide (100 μM), diphenylamin‐2‐carboxylic acid (DPC, 1 mM), or Cl− and HCO3−‐free solution whilst the fall was abolished by amiloride pretreatment. Thapsigargin (0.3 μM) abolished the UTP‐induced increase in ISC but not the subsequent decrease. Staurosporine (0.1 μM) inhibited basal ISC and blocked UTP‐induced inhibition of ISC. Inhibitors of either protein kinase C (PKC) (D‐erythro sphingosine) or PKA (H89) had no effect. This study suggests that UTP stimulates Cl− secretion and inhibits basal Na+ absorption. ATP has a similar stimulatory effect, which may be mediated by activation of P2Y2 receptors and an increase in [Ca2+]in, but no inhibitory effect, which is likely mediated by activation of a pyrimidine receptor and possible inhibition of a protein kinase other than PKC or PKA. British Journal of Pharmacology (2000) 130, 367–374; doi:10.1038/sj.bjp.0703324

  以下是文本的中文翻译： 将猪气管上皮的分离段放置于尤金箱（Ussing chamber）中，监测维持跨上皮电位差为0 mV所需的电流（短路电流，ISC），并研究核苷酸对ISC的影响。 黏膜侧的UTP（100 μM）引发短暂的ISC上升，随后出现持续30分钟的基线ISC下降。黏膜侧的ATP（100 μM）同样刺激短暂的ISC上升，但与UTP不同，它并未抑制基线ISC。而基底侧的UTP和ATP均短暂增加ISC。 预刺激UTP的上皮对ATP无反应，但以ATP预刺激并不会消除对UTP的反应。这些结果表明，上皮细胞表面存在两组受体，使核苷酸能够调节ISC。 UTP诱导的上升被预先用布美他尼（100 μM）、二苯基氨基-2-羧酸（DPC，1 mM）或无Cl−和HCO3−的溶液处理所抑制，而下降则被预先用阿米洛利处理所消除。 Thapsigargin（0.3 μM）消除了UTP诱导的ISC增加，但未影响随后的下降。Staurosporine（0.1 μM）抑制基线ISC并阻断UTP诱导的ISC抑制。蛋白激酶C（PKC）抑制剂（D-赤藓醇基鞘氨醇）或蛋白激酶A（PKA）抑制剂（H89）均无作用。 本研究表明，UTP刺激Cl−分泌并抑制基线Na+吸收。ATP具有类似的刺激作用，可能是通过激活P2Y2受体和增加[Ca2+]in介导，但无抑制作用，这可能是通过激活嘧啶受体并可能抑制其他蛋白激酶（而非PKC或PKA）。 《英国药理学杂志》 (2000), 130, 367–374; doi:10.1038/sj.bjp.0703324
• AROMATIC POLYESTER
  申请人：Muroran Institute of Technology

  公开号：EP2479203A1

  公开（公告）日：2012-07-25

  The present invention provides an aromatic polyester which is substantially free from the occurrence of coloration and retains significantly high transparency even after being thermally processed at high temperature and which has high flowability. The aromatic polyester contains a polyhydric phenol residue and a residue of any one of aromatic polycarboxylic acid, halide thereof, and anhydride thereof, and terminals of the aromatic polyester have a structure represented by the formula -C(O)-R. The aromatic polyester has an end-capping rate of 90% or higher and a weight average molecular weight (Mw) ranging from 3,000 to 1,000,000.

  本发明提供了一种芳香族聚酯，该聚酯基本上不会发生着色，即使在高温热加工后仍能保持明显的高透明度，并且具有高流动性。芳香族聚酯含有多羟基苯酚残留物和芳香族多羧酸、其卤化物和其酸酐中任意一种的残留物，芳香族聚酯的端基具有式 -C(O)-R 所代表的结构。芳香族聚酯的端盖率为 90% 或更高，重量平均分子量（Mw）为 3,000 至 1,000,000 之间。
• A Novel Synthesis of Substituted Phenylglyoxylic Acids¹
  作者：I. Moyer Hunsberger、E. D. Amstutz

  DOI：10.1021/ja01182a070

  日期：1948.2
• Yanagita, Chemische Berichte, 1938, vol. 71, p. 2269,2271
  作者：Yanagita

  DOI：——

  日期：——