5-chloro-2,5-dimethyl-hex-2-ene | 90202-20-3

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 有机氯化物
• 英文名称: 5-chloro-2,5-dimethyl-hex-2-ene
• 英文别名: 2-chloro-2,5-dimethyl-4-hexene；5-Chlor-2,5-dimethyl-hex-2-en；5-Chlor-2,5-dimethyl-2-hexen；5-Chloro-2,5-dimethylhex-2-ene
• CAS: 90202-20-3
• 化学式: C₈H₁₅Cl
• 分子量: 146.66
• InChiKey: NOAUMWXRBCAHMX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  9
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  2,5-dimethyl-4-hexen-2-ol 、 乙酰氯 生成 5-chloro-2,5-dimethyl-hex-2-ene
  参考文献：
  名称：

  Henry, Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1906, vol. 143, p. 496

  摘要：

  DOI：

文献信息

• Chiral copper complex catalyst composition and asymmetric production process using the same
  申请人：——

  公开号：US20010037036A1

  公开（公告）日：2001-11-01

  There is disclosed chiral copper complex catalyst composition, which is obtained by contacting an optically active N-salicylideneaminoalcohol compound of formula (1): 1 with a mono-valent or di-valent copper compound in an inert solvent, wherein R 1 and R 2 represent an alkyl group and the like, X 1 and X 2 represent a hydrogen atom, a halogen atom, a nitro group, an alkyl group, an alkoxy group, a cyano group or the like, and the amount of the mono-valent or di-valent copper compound is less than 1 mole per 1 mole of the optically active N-salicylideneaminoalcohol compound of formula (1), and a process for producing an optically active cylopropane-carboxylic acid ester using the same.

  披露了手性铜配合物催化剂组合物，该组合物是通过将式（1）中的光学活性N-水杨醛亚氨基醇化合物与一价或二价铜化合物在惰性溶剂中接触而获得的，其中R1和R2代表烷基基团等，X1和X2代表氢原子、卤素原子、硝基团、烷基基团、烷氧基团、氰基团等，一价或二价铜化合物的量小于1摩尔与式（1）中的光学活性N-水杨醛亚氨基醇化合物的摩尔比，以及使用该组合物生产光学活性环丙烷羧酸酯的方法。
• Asymmetric copper complex and cyclopropanation reaction using the same
  申请人：——

  公开号：US20020177718A1

  公开（公告）日：2002-11-28

  There are disclosed asymmetric copper complex comprising, as components, (a) an optically active bisoxazoline compound of formula (1): 1 wherein R 1 and R 2 are different and each represent a hydrogen atom, an alkyl group, a cycloalkyl group, or a phenyl or aralkyl group which may be substituted, R 3 and R 4 each represent a hydrogen atom, an alkyl group, a cycloalkyl group, or a phenyl or aralkyl group which may be substituted, or R 3 and R 4 may be bonded to each other to form a C 3-5 cyclic alkylene group, R 5 represents a hydrogen atom or a C 1-6 alkyl group, or the two R 5 groups may be bonded to each other to represent a C 3-5 cyclic alkylene group, (b) a monovalent or divalent copper compound, and (c) a strong acid or a Lewis acid or a mixture thereof, and a process for producing an optically active cyclopropanecarboxylate using the same.

  揭示了包括以下组分的不对称铜络合物：（a）公式（1）的手性双噁唑啉化合物：其中R1和R2不同，每个代表氢原子、烷基、环烷基、苯基或芳基烷基，可能被取代，R3和R4每个代表氢原子、烷基、环烷基、苯基或芳基烷基，可能被取代，或者R3和R4可以相互连接形成C3-5环烷基，R5代表氢原子或C1-6烷基，或者两个R5基团可以相互连接形成C3-5环烷基；（b）一价或二价铜化合物；和（c）强酸或Lewis酸或二者混合物，以及使用它们制备手性环丙烷羧酸酯的方法。
• Chiral copper complex and production processes thereof and using the same
  申请人：Kamitamari Masashi

  公开号：US20050090684A1

  公开（公告）日：2005-04-28

  There is disclosed an optically active salicylideneaminoalcohol compound of formula (1): wherein R 1 represents an alkyl group or the like, R 2 represents an aryl group and the like, and when X 1 represents a nitro, X 2 is a hydrogen atom, when X 1 represents a chlorine atom, X 2 is a chlorine atom, and when X 1 is a hydrogen atom, X 2 is a fluorine atom; and the carbon atom denoted by “*” is an asymmetric carbon atom having either an S or R configuration, and a chiral copper complex produced from the optically active salicylidenaminoalcohol compound and a copper compound.

  公开了一种光学活性的萨利基利丙氨醇化合物，其化学式为(1)：其中，R1代表烷基或类似物，R2代表芳基或类似物，当X1代表硝基时，X2是氢原子，当X1代表氯原子时，X2是氯原子，当X1是氢原子时，X2是氟原子；而由光学活性萨利基利丙氨醇化合物和铜化合物制备的手性铜络合物中，用“*”表示的碳原子是具有S或R构型的不对称碳原子。
• Process for producing optically active cyclopropanecarboxylic acid esters
  申请人：SUMITOMO CHEMICAL COMPANY LIMITED

  公开号：EP0891965A1

  公开（公告）日：1999-01-20

  A process for producing an optically active cyclopropanecarboxylic acid ester which is characterized by reacting a prochiral olefin with a diazoacetic acid ester in the presence of a copper complex obtained by reacting an optically active bisoxazoline ligand with a copper compound.

  一种生产光学活性环丙烷羧酸酯的工艺，其特征是在光学活性双噁唑啉配体与铜化合物反应得到的铜络合物存在下，使亲手性烯烃与重氮乙酸酯反应。
• Copper complexes of optically active bisoxazolines as enantioselective catalysts in cyclopropanation reactions
  申请人：Sumitomo Chemical Company, Limited

  公开号：EP0895992A2

  公开（公告）日：1999-02-10

  An optically active bisoxazoline compound of the formula [I]: wherein R1 represents an alkyl group, cycloalkyl group, aralkyl group, phenyl group which may be substituted or an alkoxy group and two geminal alkyl groups may be joined together to form a cyclic structure;    R2 represents an alkyl group , cycloalkyl group, aralkyl group or phenyl group which may be substituted;    R3 represents a hydrogen atom, (C2-C4)alkyl group or cycloalkyl group; and    the asterisk * represents an asymmetric carbon atom.

  式[I]的光学活性双噁唑啉化合物： 其中 R1 代表烷基、环烷基、芳基、可被取代的苯基或烷氧基，两个烷基可连接在一起形成环状结构； R2 代表烷基、环烷基、芳基或可被取代的苯基； R3 代表氢原子、(C2-C4)烷基或环烷基；以及 星号 * 代表不对称碳原子。