3-(3,4-二羟基苯基)-N-乙基丙酰胺 | 125789-86-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 中文名称: 3-(3,4-二羟基苯基)-N-乙基丙酰胺
• 英文名称: 3-(3,4-dihydroxyphenyl)-N-ethylpropanamide
• CAS: 125789-86-8
• 化学式: C₁₁H₁₅NO₃
• 分子量: 209.24
• InChiKey: OQUBQEQXVVOGLG-UHFFFAOYSA-N

物化性质

• 沸点：
  483.4±35.0 °C(Predicted)
• 密度：
  1.198±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -0.4
• 重原子数：
  15
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  69.6
• 氢给体数：
  3
• 氢受体数：
  3

文献信息

• COMPOSITION AND METHODS FOR TETHERING BIOACTIVE PEPTIDES TO METAL OXIDE SURFACES
  申请人：BECKER MATTHEW

  公开号：US20170189531A1

  公开（公告）日：2017-07-06

  In various aspects, embodiments of the present invention are directed to a series of multivalent dendrons containing a bioactive peptide domain and surface-binding catechol domains. In some embodiments, these multivalent dendrons were obtained through solid phase synthesis and have a strong binding affinity to metal oxide surfaces such as, TiO 2 , ZrO 2 , CeO 2 , and Fe 3 O 4 , SiO2, as well as other inorganic surfaces such as hydroxyapatite, silver, fluorapatite, calcium carbonate and gold. These catechol-bearing dendrons provide a fast and efficient method to functionalize a wide range of inorganic materials with bioactive peptides and have the potential to be used in coating orthopaedic implants and fixation devices.