(ThiqDtc)H | 46184-97-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 四氢异喹啉
• 英文名称: (ThiqDtc)H
• 英文别名: 3,4-dihydro-1H-isoquinoline-2-carbodithioic acid；TIQDTC；3,4-Dihydro-1H-isochinolin-2-dithiocarbonsaeure；3,4-dihydro-1H-isoquinoline-2-carbodithioic acid
• CAS: 46184-97-8
• 化学式: C₁₀H₁₁NS₂
• 分子量: 209.336
• InChiKey: OERKWBIGUBOPTB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  13
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  36.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  (ThiqDtc)H 以 水 、 乙腈 为溶剂， 生成 1-methyl-2-oxoindolin-3-yl 3,4-dihydroisoquinoline-2(1H)-carbodithioate
  参考文献：
  名称：

  Dithiocarbamation of spiro-aziridine oxindoles: a facile access to C3-functionalised 3-thiooxindoles as apoptosis inducing agents

  摘要：

  已经通过直接对螺环-氮杂环氧吲哚进行二硫代氨基化，实现了对C3-官能化3-硫代氧吲哚的高效访问。已经研究了它们的诱导凋亡性能。

  DOI：

  10.1039/d1ob02102h
• 作为产物：
  描述：

  二硫化碳 、 四氢异喹啉 以 乙腈 为溶剂， 生成 (ThiqDtc)H
  参考文献：
  名称：

  Dithiocarbamation of spiro-aziridine oxindoles: a facile access to C3-functionalised 3-thiooxindoles as apoptosis inducing agents

  摘要：

  已经通过直接对螺环-氮杂环氧吲哚进行二硫代氨基化，实现了对C3-官能化3-硫代氧吲哚的高效访问。已经研究了它们的诱导凋亡性能。

  DOI：

  10.1039/d1ob02102h

文献信息

• Varma, R. Hari Kumar; Prabhakaran, C. P., Indian Journal of Chemistry, Section A: Inorganic, Physical, Theoretical and Analytical, 1989, vol. 28, # 12, p. 1119 - 1121
  作者：Varma, R. Hari Kumar、Prabhakaran, C. P.

  DOI：——

  日期：——
• Liwschiz; Preobrashenskii, Zhurnal Obshchei Khimii, 1945, vol. 15, p. 925,929
  作者：Liwschiz、Preobrashenskii

  DOI：——

  日期：——
• In vitro assessment of cytotoxicity, anti-inflammatory, antifungal properties and crystal structures of metallacyclic palladium(II) complexes
  作者：Farkhanda Shaheen、Amin Badshah、Marcel Gielen、Gianluca Croce、Ulrich Florke、Dick de Vos、Saqib Ali

  DOI：10.1016/j.jorganchem.2009.10.048

  日期：2010.2

  Metallacyclic palladium(II) complexes [Pd(L)(R3P)Cl], L = TIQDTC (1,2,3,4-tetrahydroisoquinolinedithiocarbamate), 4MpipDTC (4-methylpipradinedithiocarbamate), MPizDTC (N-methylpiperazinedithiocarbamate), R3P = Ph3P, (o-tolyl)(3)P, Ph2ClP, were synthesized in a 1:1 molar metal-ligand ratio. These complexes were characterized by elemental analyses, FT-IR, multinuclear (H-1, C-13 and P-31) NMR. The X-ray crystal structures of [Pd(TIQDTC)(Ph3P)Cl] and [Pd(TIQDTC)((o-tolyl)(3)P)Cl] show a slightly distorted square planar environment around the Pd(II) ion with S-Pd-S and P-Pd-Cl average bond angles of 74.51 and 92.41, respectively. These complexes were screened for cytotoxic, antifungal, anti-inflammatory and antibacterial activity. Some complexes exhibit a significant activity against fungi. (C) 2009 Elsevier B.V. All rights reserved.
• USES OF DITHIOCARBAMATE COMPOUNDS
  申请人：VON WROCHEM Florian

  公开号：US20130264545A2

  公开（公告）日：2013-10-10

  The present invention relates to the use of dithiocarbamate compounds and to an assembly for use in an electronic device, said assembly comprising a self-assembled monolayer of at least one dithiocarbamate compound. The present invention also relates to an electronic device including such assembly.
• Method and Kit for Detecting Lead in a Solid Sample
  申请人：THE REGENTS OF THE UNIVERSITY OF MICHIGAN

  公开号：US20170052166A1

  公开（公告）日：2017-02-23

  A method and kit for detecting the presence of lead in a solid sample is disclosed. The solid sample is brought into contact with a nonaqueous solution of a dithiocarbamate capable of forming a gel upon contact with lead, with the formation of a gel showing that lead is present in the solid sample.