(Z)-1-phenyl-2-(4'-tolyl)prop-1-ene | 113312-79-1

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: (Z)-1-phenyl-2-(4'-tolyl)prop-1-ene
• 英文别名: (Z)-2-(4-methylphenyl)-1-phenylprop-1-ene；1-methyl-4-[(Z)-1-phenylprop-1-en-2-yl]benzene
• CAS: 113312-79-1
• 化学式: C₁₆H₁₆
• 分子量: 208.303
• InChiKey: MRCWYHVGXKPPLZ-OWBHPGMISA-N

物化性质

• 沸点：
  302.5±17.0 °C(Predicted)
• 密度：
  0.997±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.2
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  对甲基苯乙酮 在 硫酸 、 magnesium 、 溶剂黄146 作用下， 以 四氢呋喃 为溶剂， 反应 3.0h， 生成 (Z)-1-phenyl-2-(4'-tolyl)prop-1-ene
  参考文献：
  名称：

  Iron-catalysed tandem cross-dehydrogenative coupling (CDC) of terminal allylic C(sp3) to C(sp2) of styrene and benzoannulation in the synthesis of polysubstituted naphthalenes

  摘要：

  本研究开发了一种新型铁催化串联交叉脱氢偶联和苯并氮化工艺，用于从简单的 1,2-芳基丙烯和苯乙烯合成具有重要生物和合成意义的多取代萘衍生物，产率为中等到良好。

  DOI：

  10.1039/c2cc17330a

文献信息

• Markovnikov-Selective Hydrothiolation of Styrenes: Application to the Synthesis of Stereodefined Trisubstituted Olefins
  作者：Markku A. Savolainen、Jimmy Wu

  DOI：10.1021/ol4015909

  日期：2013.7.19

  BT-sulfones react with aromatic aldehydes to furnish trisubstituted alkenes with excellent Z stereoselectivity. These sulfones are synthesized by hydrothiolation of styrene and styrenyl derivatives (followed by oxidation). This method provides a conceptually novel way to prepare these important sulfur compounds.

  BT砜与芳族醛反应可制得具有出色Z立体选择性的三取代烯烃。这些砜是通过苯乙烯和苯乙烯基衍生物的加氢硫醇化反应（随后是氧化反应）合成的。该方法在概念上提供了制备这些重要硫化合物的新颖方法。
• Dipalladium(I) complexes of ortho- and para-functionalized 1,3-bis(aryl)triazenide ligands: Synthesis, structure and catalytic activity
  作者：Erick Correa-Ayala、Carlos Campos-Alvarado、Daniel Chávez、Simón Hernández-Ortega、David Morales-Morales、Valentín Miranda-Soto、Miguel Parra-Hake

  DOI：10.1016/j.ica.2019.03.004

  日期：2019.5

  Abstract The synthesis and characterization of a series dipalladium(I) complexes of formulae [Pd1-[2′-(methoxycarbonyl)phenyl]-3-[4′-X-phenyl]triazenide}]2 [X = F (4), Cl (5), Br (6)] are reported. The crystal structure of complex 4 was determined by X-ray diffraction studies. The previously reported dipalladium(I) 1–3 as well as the new complexes 4–6 were used as catalysts in the Heck and Suzuki

  摘要一系列[Pd 1- [2'-（甲氧羰基）苯基] -3- [4'-X-苯基]三叠氮化物]] 2 [X = F（4 ），Cl（5），Br（6）]。配合物4的晶体结构通过X射线衍射研究确定。先前报道的二钯（I）1-3和新的配合物4-6被用作不同对位取代溴苯的Heck和Suzuki偶联反应的催化剂。
• A regio- and stereoselective entry to (Z)-β-halo alkenyl sulfides and their applications to access stereodefined trisubstituted alkenes
  作者：Ge Liu、Lichun Kong、Ji Shen、Gangguo Zhu

  DOI：10.1039/c4ob00103f

  日期：——

  sulfides in high yields with excellent regio- and stereoselectivity. This approach covers a variety of substrates, including both aryl and alkyl haloalkynes. Meaningfully, it allows a facile access to stereodefined (Z)- or (E)-trisubstituted olefins featuring the iterative cross-coupling of carbon–halide and carbon–sulfur bonds of β-halo alkenyl sulfides.

  已经实现了通过K 2 CO 3促进卤代炔烃的氢硫醇化来温和有效地制备（Z）-β-卤代烯基硫化物，在高浓度下生产（Z）-β-溴和（Z）-β-氯代乙烯基硫化物。产生具有优异的区域和立体选择性的产物。该方法涵盖了多种底物，包括芳基和烷基卤代炔烃。有意义的是，它允许轻松访问立体定义的（Z）或（E）三取代的烯烃，其特征在于β-卤代烯基硫醚的卤化碳和碳硫键具有迭代交叉偶联。
• Lewis Acid Promoted Carbon−Carbon Double-Bond Formation via Organozinc Reagents and Carbonyl Compounds
  作者：Zhi-Yong Peng、Fang-Fang Ma、Lv-Feng Zhu、Xiao-Min Xie、Zhaoguo Zhang

  DOI：10.1021/jo901252z

  日期：2009.9.4

  Using cheap and readily available AlCl3 as Lewis acid, functionalized aldehydes react with organozinc reagents to give (E)-alkenes stereoselectively in high yields.
• Arylation of Styrenes with Aryliron Complexes [CpFe(CO)₂Ar]
  作者：Shigeo Yasuda、Hideki Yorimitsu、Koichiro Oshima

  DOI：10.1021/om1001952

  日期：2010.6.14

  Treatment of aryliron complexes [CpFe(CO)(2)Ar] with styrenes in boiling xylene affords the corresponding stilbenes. The aryliron complexes, which become active upon heating, serve as arylating agents in the reaction.