4-(4-Methylpiperazin-1-yl)naphthalene-1,8-dicarbonitrile | 528877-37-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪烷类
• 英文名称: 4-(4-Methylpiperazin-1-yl)naphthalene-1,8-dicarbonitrile
• 英文别名: 4-(4-methylpiperazin-1-yl)naphthalene-1,8-dicarbonitrile
• CAS: 528877-37-4
• 化学式: C₁₇H₁₆N₄
• 分子量: 276.341
• InChiKey: WLMWNOPSQGQSTF-UHFFFAOYSA-N

物化性质

• 沸点：
  515.7±50.0 °C(Predicted)
• 密度：
  1.25±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  21
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  54.1
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  5-nitro-acenaphthylene-1,2-dione 在 盐酸 、 磺酰胺 作用下， 以 乙醇 、 二甲基亚砜 为溶剂， 反应 19.5h， 生成 4-(4-Methylpiperazin-1-yl)naphthalene-1,8-dicarbonitrile
  参考文献：
  名称：

  Novel highly efficient fluoroionophores with a peri-effect and strong electron-donating receptors: TICT-promoted PET and signaling response to transition metal cations with low background emission

  摘要：

  Novel fluoroionophores with piperazine frameworks as receptors for transition metal cations have been designed with the aid of calculation and synthesized. They exhibited low background emission and highly efficient fluorescence enhancements upon complexation with different transition metal cations, which could be ascribed to the special contribution of the TICT-promoted PET processes caused by the peri-effect and strong electron-donating receptors. (C) 2003 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(03)00186-2

文献信息

• Novel highly efficient fluoroionophores with a peri-effect and strong electron-donating receptors: TICT-promoted PET and signaling response to transition metal cations with low background emission
  作者：Yi Xiao、Xuhong Qian

  DOI：10.1016/s0040-4039(03)00186-2

  日期：2003.3

  Novel fluoroionophores with piperazine frameworks as receptors for transition metal cations have been designed with the aid of calculation and synthesized. They exhibited low background emission and highly efficient fluorescence enhancements upon complexation with different transition metal cations, which could be ascribed to the special contribution of the TICT-promoted PET processes caused by the peri-effect and strong electron-donating receptors. (C) 2003 Elsevier Science Ltd. All rights reserved.