2-chloroethyl-gem-dichlorocyclopropane | 1051388-27-2

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 有机氯化物
• 英文名称: 2-chloroethyl-gem-dichlorocyclopropane
• 英文别名: 1,1-Dichloro-2-(1-chloroethyl)cyclopropane
• CAS: 1051388-27-2
• 化学式: C₅H₇Cl₃
• 分子量: 173.47
• InChiKey: UOGVGGZMCDUWRC-UHFFFAOYSA-N

物化性质

• 沸点：
  56 °C(Press: 3 mmHg)
• 密度：
  1.34±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  8
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  2-chloroethyl-gem-dichlorocyclopropane 、 正丁胺 以 二甲基亚砜 为溶剂， 反应 4.0h， 以95%的产率得到butyl[1-(2,2-dichlorocyclopropyl)ethyl]amine
  参考文献：
  名称：

  Reactions of chloroalkyl-gem-dichlorocyclopropanes with amines

  摘要：

  N-Alkylation of primary and secondary amines with monochloroalkyl-gem-dichlorocyclopropanes under conditions of thermal and microwave heating results in the corresponding amino-gem-dichlorocyclopropanes. With microwave irradiation heating, the reaction time has been decreased to 1 h, the yields of the amines containing gem-dichlorocyclopropane moiety being the same. Formation of the bicyclic amine in reaction of cis-2,3-dichloromethyl-gem-dichlorocyclopropane with primary amines under conditions of phasetransfer catalysis has been studied.

  DOI：

  10.1134/s1070363214010058
• 作为产物：
  描述：

  3-氯-1-丁烯 、 氯仿 在 苄基三乙基氯化铵 、 sodium hydroxide 作用下， 以 水 为溶剂， 以90%的产率得到2-chloroethyl-gem-dichlorocyclopropane
  参考文献：
  名称：

  Reactions of chloroalkyl-gem-dichlorocyclopropanes with amines

  摘要：

  N-Alkylation of primary and secondary amines with monochloroalkyl-gem-dichlorocyclopropanes under conditions of thermal and microwave heating results in the corresponding amino-gem-dichlorocyclopropanes. With microwave irradiation heating, the reaction time has been decreased to 1 h, the yields of the amines containing gem-dichlorocyclopropane moiety being the same. Formation of the bicyclic amine in reaction of cis-2,3-dichloromethyl-gem-dichlorocyclopropane with primary amines under conditions of phasetransfer catalysis has been studied.

  DOI：

  10.1134/s1070363214010058

文献信息

• 3-(SUBSTITUTED PHENYL)-5-(SUBSTITUTED CYCLOPROPYL)-1,2,4-TRIAZOLE COMPOUNDS
  申请人：Dow AgroSciences LLC

  公开号：EP1123281A1

  公开（公告）日：2001-08-16
• [EN] 3-(SUBSTITUTED PHENYL)-5-(SUBSTITUTED CYCLOPROPYL)-1,2,4-TRIAZOLE COMPOUNDS<br/>[FR] COMPOSES 3-(PHENYL SUBSTITUE)-5-(CYCLOPROPYL SUBSTITUE)-1,2,4-TRIAZOLE
  申请人：DOW AGROSCIENCES LLC

  公开号：WO2000024720A1

  公开（公告）日：2000-05-04

  3-(Substituted phenyl)-5-(substituted cyclopropyl)-1,2,4-triazole compounds are useful as insecticides and acaricides. New synthetic procedures and intermediates for preparing the compounds, pesticide compositions containing the compounds, and methods of controlling insects and mites using the compounds are also provided.
• Reactions of chloroalkyl-gem-dichlorocyclopropanes with amines
  作者：E. K. Aminova、A. N. Kazakova、N. N. Mikhailova、S. S. Zlotskii

  DOI：10.1134/s1070363214010058

  日期：2014.1

  N-Alkylation of primary and secondary amines with monochloroalkyl-gem-dichlorocyclopropanes under conditions of thermal and microwave heating results in the corresponding amino-gem-dichlorocyclopropanes. With microwave irradiation heating, the reaction time has been decreased to 1 h, the yields of the amines containing gem-dichlorocyclopropane moiety being the same. Formation of the bicyclic amine in reaction of cis-2,3-dichloromethyl-gem-dichlorocyclopropane with primary amines under conditions of phasetransfer catalysis has been studied.