3-(丁基氨基)丙烷-1,2-二醇 | 60278-95-7

• 分子结构分类: 有机化合物 - 有机氮化合物
• 中文名称: 3-(丁基氨基)丙烷-1,2-二醇
• 英文名称: 1-(N-n-butylamino)propane-2,3-diol
• 英文别名: 3-butylaminopropane-1,2-diol；3-(butylamino)propane-1,2-diol
• CAS: 60278-95-7
• 化学式: C₇H₁₇NO₂
• mdl: MFCD00128133
• 分子量: 147.217
• InChiKey: LWIPMLPWRZUQQH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.3
• 重原子数：
  10
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  52.5
• 氢给体数：
  3
• 氢受体数：
  3

安全信息

• 海关编码：
  2922199090

反应信息

• 作为反应物：
  描述：

  2-[3-氰基-4-(4-氟苯基)-5,5-二甲基-5H-呋喃-2-基]丙二腈 、 3-(丁基氨基)丙烷-1,2-二醇 在 吡啶 作用下， 生成
  参考文献：
  名称：

  Modifications of DCDHF single molecule fluorophores to impart water solubility

  摘要：

  A series of dicyanomethylenedihydrofuran (DCDHF) fluorophores with different hydrophilic groups were synthesized and their photophysical properties and water solubilities were measured. Significant water solubility was achieved without compromising desirable photophysical properties, permitting applications of these fluorophores in biological systems. (c) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2007.03.026
• 作为产物：
  描述：

  在 硫酸 、 水 作用下， 反应 8.0h， 生成 3-(丁基氨基)丙烷-1,2-二醇
  参考文献：
  名称：

  The reaction of sulfamic acid derivatives with epoxides. 4. Hydrolysis of 3-chloro-2-hydroxypropylsulfamates

  摘要：

  DOI：

  10.1007/bf01431142

文献信息

• 1,2-디올 구조의 폴리올 유도체 화합물과 그 제조방법 및 이를 함유하는 항균 조성물
  申请人：ABNC Corporation 주식회사 에이비앤씨(120130621588) Corp. No ▼ 220111-0080613BRN ▼616-81-83412

  公开号：KR20190088171A

  公开（公告）日：2019-07-26

  본 발명은 하기 화학식 1로 표시되는 1,2-디올 구조를 갖는 폴리올 유도체 화합물, 그 제조방법, 및 상기 화합물을 유효성분으로 함유하는 항균 조성물에 관한 것이다. [화학식 1] 상기 식에서, R1은 나이트로전(N) 또는 설퍼(S) 이고, R2는 OH 또는 C2 알킬이다. 본 발명에 따르면, 상기 화학식 1로 표시되는 1,2-디올 구조를 갖는 폴리올 유도체 화합물은 기존의 폴리올 중에서 가장 좋은 항균력을 나타낸다고 알려진 1,2-헥산디올보다 우수한 항균력을 나타내므로, 식품, 의약품, 화장품 등의 많은 제품들은 미생물에 의한 부패를 막아주는 방부제로서 효과적으로 사용될 수 있다.

  本发明涉及具有以下化学式1所示的1,2-二醇结构的聚醇衍生物化合物，其制备方法以及含有该化合物作为有效成分的抗菌组合物。[化学式1] 在上述式中，R1是氮基(N)或硫基(S)，R2是OH或C2烷基。根据本发明，具有化学式1所示的1,2-二醇结构的聚醇衍生物化合物显示出比已知的对1,2-己二醇具有更优越的抗菌性能，因此，许多产品，如食品、药品、化妆品等，可以有效地用作防腐剂，以防止微生物引起的腐败。
• Pyrimidine compounds
  申请人：——

  公开号：US20030114473A1

  公开（公告）日：2003-06-19

  Pyrimidine derivatives of the formula (I) wherein: one of Q 1 and Q 2 or both of Q 1 and Q 2 is substituted on a ring carbon by one substituent of the formula (Ia) [provided that when present in Q 1 the substituent of formula (Ia) is not adjacent to the —NH— link]; wherein Q 1 , Q 2 , G, R 1 , X, Y 1 , Y 2 , Z, n and m are as described within; and pharmaceutically acceptable salts and in vivo hydrolysable esters thereof are described. Processes for their manufacture, pharmaceutical compositions and their use as cyclin-dependent serine/threonine kinase (CDK) and focal adhesion kinase (FAK) inhibitors are also described. 1

  式(I)的嘧啶衍生物，其中：Q1和Q2中的一个或两个被式(Ia)的一个取代基取代在环碳上[前提是当式(Ia)的取代基存在于Q1中时，不与—NH—连接相邻]; 其中Q1、Q2、G、R1、X、Y1、Y2、Z、n和m如所述；以及其药学上可接受的盐和体内可水解酯。还描述了它们的制造工艺、药物组合物以及它们作为细胞周期依赖性丝氨酸/苏氨酸激酶(CDK)和焦点粘附激酶(FAK)抑制剂的用途。
• COMPOSITION AND METHOD FOR PRODUCING SAME
  申请人：Daicel Corporation

  公开号：EP4095125A1

  公开（公告）日：2022-11-30

  Provided is a composition having moderate viscosity for coating properties and ejection properties, being applicable for firing at low temperatures, and leaving an extremely small amount of ash after firing. The composition of the present disclosure contains a miscible material of a compound represented by Formula (1) below and a compound (A) represented by Formula (A) below. In Formula (1) below, R1 represents a linear aliphatic hydrocarbon group having from 10 to 25 carbons; R2 and R3 are identical or different and represent an aliphatic hydrocarbon group having 2, 4, 6, or 8 carbons; R4 represents an aliphatic hydrocarbon group having from 1 to 8 carbons; R5 and R6 are identical or different and represent an aliphatic hydrocarbon group having from 1 to 3 carbons or a hydroxyalkyl ether group; and L1 to L3 represent an amide bond. In Formula (A) below, in the formula, Ra and Rc are identical or different and represent a hydrogen atom or an aliphatic hydrocarbon group that has from 1 to 12 carbons and may have a substituent; Rb represents an aliphatic hydrocarbon group that has from 1 to 12 carbons and may have a substituent; and the substituents are each an amino group and/or a hydroxyl group.

  本发明提供了一种组合物，该组合物具有适中的粘度，具有涂覆性能和弹射性能，适用于低温烧制，烧制后留下的灰烬量极少。本公开的组合物含有下式（1）代表的化合物和下式（A）代表的化合物（A）的混溶材料。在下式（1）中，R1 代表具有 10 至 25 个碳原子的线性脂族烃基；R2 和 R3 相同或不同，代表具有 2、4、6 或 8 个碳原子的脂族烃基；R4 代表具有 1 至 8 个碳原子的脂族烃基；R5 和 R6 相同或不同，代表具有 1 至 3 个碳原子的脂族烃基或羟基烷基醚基；L1 至 L3 代表酰胺键。在下式（A）中，式中 Ra 和 Rc 相同或不同，代表氢原子或碳原子数为 1 至 12 个且可带有取代基的脂族烃基；Rb 代表碳原子数为 1 至 12 个且可带有取代基的脂族烃基；取代基分别为氨基和/或羟基。
• DISPERSION MEDIUM FOR METAL PARTICLE SINTERING, AND ELECTROCONDUCTIVE PASTE
  申请人：Daicel Corporation

  公开号：EP4108360A1

  公开（公告）日：2022-12-28

  Provided are a dispersion medium for metal particle sintering that gives an electroconductive paste whereby metal particles are satisfactorily sintered at a low temperature even when not in a reducing atmosphere, and an electroconductive paste in which the dispersion medium is used. The dispersion medium for metal particle sintering according to an embodiment of the present disclosure contains formic acid and a basic compound, the basic compound being a nitrogen-containing compound represented by Formula (1), and a molar ratio (basic group/formic acid) of basic groups included in the basic compound to formic acid being from 0.50 to 1.20. [Formula 1] In Formula (1): Ra to Rc are the same or different and each represent a hydrogen atom or a hydrocarbon group that may have a substituent; the double line including a dashed line represents a single bond or a double bond, with Rc being absent in the case of a double bond; and any two of Ra to Rc may bond with each other and form a ring together with the adjacent nitrogen atom.

  本发明提供了一种用于金属颗粒烧结的分散介质，该分散介质可提供一种导电浆料，即使不在还原气氛中，金属颗粒也能在低温下得到令人满意的烧结，本发明还提供了一种使用该分散介质的导电浆料。根据本公开的一个实施方案，用于金属颗粒烧结的分散介质含有甲酸和碱性化合物，碱性化合物是由式（1）表示的含氮化合物，碱性化合物中包含的碱性基团与甲酸的摩尔比（碱性基团/甲酸）为 0.50 至 1.20。[式 1] 式（1）中：Ra至Rc相同或不同，各自代表氢原子或可能具有取代基的烃基；包括虚线的双线代表单键或双键，在双键的情况下Rc不存在；Ra至Rc中的任意两个可以相互键合，并与相邻的氮原子一起形成环。
• Carbonylation of .beta.-aminoethanols, diols, and diolamines
  作者：Wilson Tam

  DOI：10.1021/jo00365a024

  日期：1986.7