Phosphorsaeure-(2-phthalimido-ethylester) | 26923-13-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异吲哚及其衍生物
• 英文名称: Phosphorsaeure-(2-phthalimido-ethylester)
• 英文别名: 2-Phthalimidoethylphosphorsaeure；2-(N-phthalimido)ethyl phosphate；phosphoric acid mono-[2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-ethyl] ester；1H-Isoindole-1,3(2H)-dione, 2-[2-(phosphonooxy)ethyl]-；2-(1,3-dioxoisoindol-2-yl)ethyl dihydrogen phosphate
• CAS: 26923-13-7
• 化学式: C₁₀H₁₀NO₆P
• 分子量: 271.166
• InChiKey: FSXKJPCXJQCRRP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.3
• 重原子数：
  18
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  104
• 氢给体数：
  2
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  、 Phosphorsaeure-(2-phthalimido-ethylester) 生成
  参考文献：
  名称：

  WO2005/82144

  摘要：

  公开号：

文献信息

• METHYLATION INHIBITOR COMPOUNDS
  申请人：The Government of the United States of America, represented by the Secretary, Department of Health and Human Services

  公开号：EP1718150A1

  公开（公告）日：2006-11-08
• US3985875A
  申请人：——

  公开号：US3985875A

  公开（公告）日：1976-10-12
• [EN] CHEMICAL COMPOUNDS FOR THE INHIBITION OF UNDESIRED CELL PROLIFERATION AND USE THEREOF<br/>[FR] COMPOSES CHIMIQUES POUR L'INHIBITION DE PROLIFERATION CELLULAIRE INDESIRABLE ET LEURS UTILISATION
  申请人：JERINI AG

  公开号：WO2005080406A2

  公开（公告）日：2005-09-01

  The present invention is related to compounds having the formula (I), wherein R1, R2, R3, R4, R5, X1, X2, T, U, V, W, Y and n are as defined in the claims, pharmaceutical compositions comprising the compounds and the use of the compounds for manufacturing a medicament for the use in the treatment of diseases involving an abnormal cell proliferation, an undesired cell proliferation, an abnormal mitosis and/or an undesired mitosis, the disease being selected from neurodegenerative diseases, stroke, inflammatory diseases, immune based disorders, infectious diseases, heart diseases, cardiovascular diseases and cell proliferative diseases.
• [EN] METHYLATION INHIBITOR COMPOUNDS<br/>[FR] COMPOSES INHIBITEURS DE METHYLATION
  申请人：US GOV HEALTH & HUMAN SERV

  公开号：WO2005082144A1

  公开（公告）日：2005-09-09

  Phospho-derivative compounds and compositions having those compounds are provided herein, as well as methods of making and using them. The compounds and compositions herein are useful in treatment or modulation of disease, disease symptoms or conditions in a subject, including in treatment or modulation of cancer, cancer symptoms or cancer conditions in a subject.
• WO2005/82144
  申请人：——

  公开号：——

  公开（公告）日：——