Tetrabutylammonium dichloroaurate(i)

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: Tetrabutylammonium dichloroaurate(i)
• 英文别名: chlorogold;tetrabutylazanium;chloride
• 化学式: C16H36AuCl2N
• 分子量: 510.3
• InChiKey: XZONJCOZEGOEDY-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  6.38
• 重原子数：
  20
• 可旋转键数：
  12
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• Gypsum board with a fluorine-containing antifungal agent
  申请人：Toreki William

  公开号：US20090104144A1

  公开（公告）日：2009-04-23

  A novel gypsum board having improved antifungal properties is disclosed. The board comprises a gypsum core, front and back paper facings, and a polymeric antifungal agent effective at inhibiting fungal growth. A preferred polymeric antifungal agent is polyDADMAC or polyTMMC. The novel gypsum board further comprises a non-polymeric antifungal agent comprising a fluorine-containing quaternary ammonium compound. Preferred non-polymeric ammonium compounds include Tetra-n-butylammonium fluoride and Tetraethylammonium fluoride. The polymeric antifungal agent can be present in the gypsum core and/or on one or both of the paper facings. The non-polymeric antifungal agent may be encapsulated in a material or ionically associated with the polymeric antifungal agent to allow releases of the non-polymeric antifungal agent over time and/or upon exposure to moisture. Methods for preparing the aforementioned novel gypsum board are also disclosed.

  揭示了一种具有改进抗真菌性能的新型石膏板。该板包括石膏芯、正面和背面纸面以及一种聚合物抗真菌剂，有效地抑制真菌生长。首选的聚合物抗真菌剂是聚DADMAC或聚TMMC。该新型石膏板还包括一种非聚合物抗真菌剂，包括含氟季铵化合物。首选的非聚合物铵化合物包括四正丁基氟化铵和四乙基氟化铵。聚合物抗真菌剂可以存在于石膏芯中和/或在正面和/或背面纸面的一侧或两侧。非聚合物抗真菌剂可以封装在材料中或离子地与聚合物抗真菌剂结合，以允许随时间释放非聚合物抗真菌剂和/或在暴露于湿气时释放。还公开了制备上述新型石膏板的方法。
• METHOD FOR PRODUCING OPTICALLY ACTIVE 2, 3-BISPHOSPHINOPYRAZINE DERIVATIVE AND METHOD FOR PRODUCING OPTICALLY ACTIVE PHOSPHINE TRANSITION METAL COMPLEX
  申请人：NIPPON CHEMICAL INDUSTRIAL CO., LTD.

  公开号：US20200087330A1

  公开（公告）日：2020-03-19

  In the method for producing an optically active 2,3-bisphosphinopyrazine derivative of the present invention, an optically active 2,3-bisphosphinopyrazine derivative represented by the following formula (3) is produced by the step of: preparing solution A containing 2,3-dihalogenopyrazine represented by the following formula (1) and a carboxylic acid amide coordinating solvent, lithiating an optically active R- or S-isomer of a hydrogen-phosphine borane compound represented by the following formula (2) to give a lithiated phosphine borane compound; adding solution B containing the lithiated phosphine borane compound to the solution A to perform an aromatic nucleophilic substitution reaction; and then performing a deboranation reaction. (For symbols in the formulas, see the description.)

  在本发明的制备光学活性2,3-双磷酸吡嗪衍生物的方法中，通过以下步骤制备了由以下式（3）表示的光学活性2,3-双磷酸吡嗪衍生物：制备含以下式（1）表示的2,3-二卤代吡嗪和一个羧酸酰胺配位溶剂的溶液A，对一个羟基磷腈硼烷化合物的光学活性R-或S-异构体（以下式（2）表示）进行锂化以得到锂化的磷腈硼烷化合物；将含有锂化的磷腈硼烷化合物的溶液B加入溶液A中进行芳香核亲核取代反应；然后进行去硼反应。（有关公式中的符号，请参见描述。）
• METHOD FOR PRODUCING 2,3-BISPHOSPHINOPYRAZINE DERIVATIVE, AND METHOD FOR PRODUCING PHOSPHINE TRANSITION METAL COMPLEX
  申请人：Nippon Chemical Industrial Co., Ltd.

  公开号：US20200247833A1

  公开（公告）日：2020-08-06

  There is provided a method for producing a 2,3-bisphosphinopyrazine derivative, the method comprising a first step of adding a base to a liquid comprising: 2,3-dihalogenopyrazine represented by the following general formula (1); a hydrogen-phosphine borane compound represented by the following general formula (2); and a deboranating agent, and allowing the resultant to react to thereby obtain the 2,3-bisphosphinopyrazine derivative represented by the following general formula (3). According to the present invention, a method for producing the industrially advantageous 2,3-bisphosphinopyrazine derivative can be provided.

  提供了一种制备2,3-双膦基吡嗪衍生物的方法，该方法包括以下步骤：第一步向液体中添加碱，所述液体包括以下通式（1）所表示的2,3-二卤代吡嗪；以下通式（2）所表示的氢膦硼烷化合物；以及脱硼试剂，然后使所得产物反应，从而得到以下通式（3）所表示的2,3-双膦基吡嗪衍生物。根据本发明，可以提供一种制备工业上有利的2,3-双膦基吡嗪衍生物的方法。
• ANTI-CANCER AGENT
  申请人：Oohara Nobuhiko

  公开号：US20120252762A1

  公开（公告）日：2012-10-04

  The anti-cancer agent of the present invention contains at least one kind of phosphine transition metal complex selected from a group of compounds represented by the following Formulae (1a) to (1d). According to this anti-cancer agent, an anti-cancer agent is provided which has a higher anti-cancer activity and lower toxicity compared to anti-cancer agents in the related art. In Formulae (1a), (1b), (1c), and (1d), R 1 and R 2 represent a linear or branched alkyl group, and R 4 has a higher priority than R 2 as ranked according to RS notation. R 3 and R 4 represent a hydrogen atom or a linear or branched alkyl group. M represents an atom of a transition metal selected from a group consisting of gold, copper, and silver. X − represents an anion.

  本发明的抗癌剂包含至少一种从以下式（1a）到（1d）所表示的化合物组中选择的膦过渡金属配合物。根据这种抗癌剂，提供了一种具有比相关技术中的抗癌剂更高的抗癌活性和较低毒性的抗癌剂。在式（1a），（1b），（1c）和（1d）中，R1和R2表示线性或支链烷基，R4按照RS符号的排序具有比R2更高的优先级。R3和R4表示氢原子或线性或支链烷基。M表示从金、铜和银组成的过渡金属的原子。X-表示阴离子。
• PHOSPHINE TRANSITION METAL COMPLEX, METHOD FOR PRODUCING SAME AND ANTITUMOR AGENT CONTAINING SAME
  申请人：Nippon Chemical Industrial Co., Ltd.

  公开号：EP1958951A1

  公开（公告）日：2008-08-20

  A phosphine transition metal complex is expressed by general formula (1): wherein A represents a groups selected from among alkylene, phenylene, and cis-vinylene; M represents an atom selected from the group consisting of gold, silver, copper, and platinum; B1 and B2 each represent a substituted or unsubstituted heterocyclic group containing a trivalent phosphorus atom forming a covalent bond with A and coordinating with M; and C represents an anionic atom.

  过渡金属膦络合物用通式（1）表示： 其中，A 代表选自亚烷基、亚苯基和顺式乙烯基的基团；M 代表选自金、银、铜和铂的原子；B1 和 B2 分别代表含有与 A 形成共价键并与 M 配位的三价磷原子的取代或未取代杂环基团；C 代表阴离子原子。