9-fluorenylmethyl fluoroformate | 229957-52-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 芴
• 英文名称: 9-fluorenylmethyl fluoroformate
• 英文别名: 9H-fluoren-9-ylmethyl carbonofluoridate
• CAS: 229957-52-2
• 化学式: C₁₅H₁₁FO₂
• 分子量: 242.25
• InChiKey: MMFDZMQPYZNPNV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  18
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.13
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• INSULIN ANALOGUES
  申请人：Robinson Andrea

  公开号：US20120225811A1

  公开（公告）日：2012-09-06

  A dicarba analogue of insulin comprising an A-chain and a B-chain or fragments, salts, solvates, derivatives, isomers or tautomers of the A-chain, the B-chain or both, provided that the dicarba analogue is not [A7,B7-(2,7-diaminosuberoyl]-des-(B26-B30)-insulin B25-amide.

  一种二卡巴胰岛素类似物，包括A链和B链或其片段，盐，溶剂化合物，衍生物，同分异构体或互变异构体，但前提是该二卡巴类似物不是[A7，B7-（2,7-二氨基戊二酰基）-去除（B26-B30）-胰岛素B25酰胺。
• Inhibitors of serine proteases
  申请人：VERTEX PHARMACEUTICALS INCORPORATED

  公开号：EP2366704A1

  公开（公告）日：2011-09-21

  The present invention relates to compounds of formula (I): or pharmaceutically acceptable salts or mixture thereof that inhibit serine protease activity, particularly the activity of hepatitis C virus NS3-NS4A protease.

  本发明涉及式（I）化合物：或其药学上可接受的盐或混合物，可抑制丝氨酸蛋白酶活性，特别是丙型肝炎病毒 NS3-NS4A 蛋白酶的活性。
• Compound Having Amino Acid Residue or Peptide Residue and Process for Producing the Same
  申请人：Ikeda Hisafumi

  公开号：US20080234464A1

  公开（公告）日：2008-09-25

  An object of the present invention is to provide a compound with a structure wherein amino acid or oligopeptide side chains are bonded to a main chain. The present invention provides a compound represented by the following formula (1). wherein n1 to n3, and m1 to m6 are certain integers; Y is a hydroxyl or an amino group; E is N or CH; R is an amino acid residue, or a peptide residue consisting of 2 to 100 amino acid residues; and L is a hydrogen atom, a group containing a lipid group, a group containing a fatty acid residue, or a group containing a fluorescent group.
• US7339023B2
  申请人：——

  公开号：US7339023B2

  公开（公告）日：2008-03-04
• US8748570B2
  申请人：——

  公开号：US8748570B2

  公开（公告）日：2014-06-10