33-Tetradecoxy-10,13,16,19,22-pentaoxa-3,29,35-triazatetracyclo[29.3.1.04,9.023,28]pentatriaconta-1(34),4,6,8,23,25,27,31(35),32-nonaene | 1393660-78-0

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 33-Tetradecoxy-10,13,16,19,22-pentaoxa-3,29,35-triazatetracyclo[29.3.1.04,9.023,28]pentatriaconta-1(34),4,6,8,23,25,27,31(35),32-nonaene
• 英文别名: 33-tetradecoxy-10,13,16,19,22-pentaoxa-3,29,35-triazatetracyclo[29.3.1.04,9.023,28]pentatriaconta-1(34),4,6,8,23,25,27,31(35),32-nonaene
• CAS: 1393660-78-0
• 化学式: C₄₁H₆₁N₃O₆
• 分子量: 691.952
• InChiKey: JNPOSZACEIUCKE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.8
• 重原子数：
  50
• 可旋转键数：
  14
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.59
• 拓扑面积：
  92.3
• 氢给体数：
  2
• 氢受体数：
  9

反应信息

• 作为产物：
  描述：

  dimethyl 4-hydroxypyridine-2,6-dicarboxylate 在 selenium(IV) oxide 、 sodium tetrahydroborate 、 硼烷四氢呋喃络合物 、 dibenzylammonium hexafluorophosphate 作用下， 以 四氢呋喃 、 1,4-二氧六环 、 甲醇 、 乙腈 为溶剂， 反应 44.0h， 生成 33-Tetradecoxy-10,13,16,19,22-pentaoxa-3,29,35-triazatetracyclo[29.3.1.04,9.023,28]pentatriaconta-1(34),4,6,8,23,25,27,31(35),32-nonaene
  参考文献：
  名称：

  Synthesis of [2]Catenanes by Template-Directed Clipping Approach

  摘要：

  A series of [2]catenanes were efficiently synthesized in high yields by a template-directed clipping approach with the formation of one macrocycle around another macrocycle containing a dialkylammonium recognition site. Their structures were identified by the NMR spectra and ESI mass spectrometry, and their geometries were investigated by the theoretical calculation.

  DOI：

  10.1021/jo3012804

文献信息

• Tetraphenylethene modified [n]rotaxanes: synthesis, characterization and aggregation-induced emission behavior
  作者：Guoxing Liu、Di Wu、Jinhua Liang、Xie Han、Sheng Hua Liu、Jun Yin

  DOI：10.1039/c5ob00068h

  日期：——

  A series of novel [n]rotaxanes based on a tetraphenylethene (TPE) backbone were constructed by a template-directed clipping approach and their structures were well-characterized.

  一系列基于四苯乙烯（TPE）骨架的新型[ n ]轮烷通过模板引导的剪接方法构建，并且它们的结构得到了良好的表征。
• Construction of Hetero[<i>n</i>]rotaxanes by Use of Polyfunctional Rotaxane Frameworks
  作者：Ziyong Li、Guoxing Liu、Wen Xue、Di Wu、Ying-Wei Yang、Jishan Wu、Sheng Hua Liu、Juyoung Yoon、Jun Yin

  DOI：10.1021/jo402166y

  日期：2013.11.15

  Heterorotaxanes, one class of topological organic structures, have attracted increasing interesting during the past two decades. In general, two types of heterorotaxane structures exist, one in which two or more different macrocycles are threaded onto one dumbbell-shaped molecule and the other where one macrocycle is threaded onto two or more different dumbbell-shaped molecules. In comparison to these

  在过去的二十年中，异戊烷类是一类拓扑有机结构，引起了越来越多的兴趣。通常，存在两种类型的杂轮烷结构，其中一种或多种大环化合物被旋接到一个哑铃形分子上，而另一种杂环被一种或多种大环化合物旋入两个或更多不同的哑铃形分子上。与这些传统类型相比，可以设想另一个拓扑有趣的异轮烷家族，它们来自同时具有宿主（冠醚）和客体（铵模板）的多官能分子。在本研究中，我们探索了这个新的杂环烷家族的选定成员的结构，该家族具有冠状醚部分，这些冠状醚部分包裹在哑铃形分子周围。这些结构是通过以下途径制备的：在这些途径中，涉及模板导向的剪切反应或烯烃复分解反应的“缝合”过程用于安装环绕铵阳离子中心的冠醚环系统。然后，接着执行穿线跟随塞紧的顺序，以安装第二个环绕的冠状醚环。结果表明，多功能积木的组装效率很高。最后，这项研究为将来的研究奠定了基础，这些研究旨在构建更复杂的杂环烷结构，例如可切换系统，自组装聚合物和功能分子机器。用
• Dendritic [2]Rotaxanes: Synthesis, Characterization, and Properties
  作者：Guoxing Liu、Ziyong Li、Di Wu、Wen Xue、Tingting Li、Sheng Hua Liu、Jun Yin

  DOI：10.1021/jo402428y

  日期：2014.1.17

  Subsequently, they were used to construct the corresponding [2]rotaxanes by a template-directed clipping approach. Unusually, two unsymmetrical dendritic [2]rotaxanes containing fluorophore (pyrene units) were also obtained; their optical properties, such as UV/vis absorption and fluorescence, were measured. The results indicate that these two rotaxanes possess stronger intermolecular interaction in the solid

  已经设计并合成了一系列树枝状铵盐。随后，它们被用于通过模板导向的剪切方法来构建相应的[2]轮烷。异常地，还获得了两种不对称的含有荧光团（py单元）的树枝状[2]轮烷。测量了它们的光学性质，例如紫外线/可见光吸收和荧光。结果表明，这两种轮烷在固态中比在溶液中具有更强的分子间相互作用。结果，高浓度的溶液容易形成准分子。这些特殊的轮烷可能会应用于动态荧光响应材料中，并且轮烷结构也将被用作调整荧光分子聚集行为的策略。
• Synthesis of [2]Catenanes by Template-Directed Clipping Approach
  作者：Ziyong Li、Wenju Liu、Jishan Wu、Sheng Hua Liu、Jun Yin

  DOI：10.1021/jo3012804

  日期：2012.8.17

  A series of [2]catenanes were efficiently synthesized in high yields by a template-directed clipping approach with the formation of one macrocycle around another macrocycle containing a dialkylammonium recognition site. Their structures were identified by the NMR spectra and ESI mass spectrometry, and their geometries were investigated by the theoretical calculation.