2,3-bis(4-hydroxyphenyl)-2-butene | 133633-63-3

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: 2,3-bis(4-hydroxyphenyl)-2-butene
• 英文别名: 4-[(Z)-3-(4-hydroxyphenyl)but-2-en-2-yl]phenol
• CAS: 133633-63-3
• 化学式: C₁₆H₁₆O₂
• 分子量: 240.302
• InChiKey: XPINIPXARSNZDM-QXMHVHEDSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  18
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  对羟基苯乙酮 在 titanium(III) chloride 、 锌 作用下， 以 四氢呋喃 为溶剂， 反应 6.0h， 生成 trans-2,3-bis(4-hydroxyphenyl)-2-butene 、 2,3-bis(4-hydroxyphenyl)-2-butene
  参考文献：
  名称：

  Shadakshari; Rele; Nayak, Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2004, vol. 43, # 9, p. 1934 - 1938

  摘要：

  DOI：

文献信息

• KINASE INHIBITOR COMPOUNDS
  申请人：Sayeski Peter P.

  公开号：US20110301159A1

  公开（公告）日：2011-12-08

  The disclosure relates to novel compounds that are capable of modulating Jak2 kinase activities, compounds that have therapeutic use in treating or preventing a subject suffering from or susceptible to a Jak2 mediated disease or disorder, and methods of use and compositions thereof.
• VIMENTIN AS A BIOMARKER FOR THE PROGRESSION OF MYELOPROLIFERATIVE NEOPLASMS
  申请人：University of Florida Research Foundation

  公开号：US20140248634A1

  公开（公告）日：2014-09-04

  The disclosure relates to novel compounds that are capable of modulating Jak2 kinase activities, compounds that have therapeutic use in treating or preventing a subject suffering from or susceptible to a Jak2 mediated disease or disorder, and methods of use and compositions thereof.
• [EN] KINASE INHIBITOR COMPOUNDS<br/>[FR] COMPOSÉS INHIBITEURS DE KINASE
  申请人：UNIV FLORIDA

  公开号：WO2010068710A2

  公开（公告）日：2010-06-17

  The disclosure relates to novel compounds that are capable of modulating Jak2 kinase activities, compounds that have therapeutic use in treating or preventing a subject suffering from or susceptible to a Jak2 mediated disease or disorder, and methods of use and compositions thereof.
• [EN] VIMENTIN AS A BIOMARKER FOR THE PROGRESSION OF MYELOPROLIFERATIVE NEOPLASMS<br/>[FR] UTILISATION DE LA VIMENTINE COMME BIOMARQUEUR DE L'ÉVOLUTION DES NÉOPLASMES MYÉLOPROLIFÉRATIFS
  申请人：UNIV FLORIDA

  公开号：WO2013019655A2

  公开（公告）日：2013-02-07

  The disclosure relates to novel compounds that are capable of modulating Jak2 kinase activities, compounds that have therapeutic use in treating or preventing a subject suffering from or susceptible to a Jak2 mediated disease or disorder, and methods of use and compositions thereof.
• Shadakshari; Rele; Nayak, Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2004, vol. 43, # 9, p. 1934 - 1938
  作者：Shadakshari、Rele、Nayak、Chattopadhyay

  DOI：——

  日期：——