Pyrimido[1,6-a]benzimidazole | 4745-92-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 咪唑并嘧啶类
• 英文名称: Pyrimido[1,6-a]benzimidazole
• CAS: 4745-92-0
• 化学式: C₁₀H₇N₃
• 分子量: 169.18
• InChiKey: WSTSOUOPIHOQCP-UHFFFAOYSA-N

物化性质

• 密度：
  1.31±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  13
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  30.2
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• SUBSTITUTED HETEROCYCLES AS JANUS KINASE INHIBITORS
  申请人：Incyte Corporation

  公开号：EP2121692B1

  公开（公告）日：2013-04-10
• [EN] ANTIBACTERIAL TARGETS IN ALLOIOCOCCUS OTITIDIS<br/>[FR] CIBLES ANTIBACTERIENNE DE L'ALLOIOCOCCUS OTITIDIS
  申请人：WYETH CORP

  公开号：WO2003104391A2

  公开（公告）日：2003-12-18

  The present invention relates to the identification of polynucleotide sequences encoding polypeptides of Alloiococcus otitidis that are essential for the growth and survival of the bacteria. In particular, the invention relates to polypeptides encoded by the Alloiococcus otitidis open reading frames (ORFs), and to their use in pharmaceutical compositions, therapeutics, diagnostics and the like. The present invention also relates to methods for identifying pharmaceutical compounds that inhibit the activity of the polypeptides that are essential for the growth ofAlloiococcus otitidis, to pharmaceutical compositions containing these compounds and to their use in treatment and amelioration of diseases caused by Alloiococcus otitidis