3-bromo-5-methylsalicylaldehyde rhodamine B hydrazone | 1619925-29-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: 3-bromo-5-methylsalicylaldehyde rhodamine B hydrazone
• CAS: 1619925-29-9
• 化学式: C₃₆H₃₇BrN₄O₃
• 分子量: 653.619
• InChiKey: BWLGZVOUAIKNNM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.04
• 重原子数：
  44.0
• 可旋转键数：
  8.0
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.28
• 拓扑面积：
  68.61
• 氢给体数：
  1.0
• 氢受体数：
  6.0

反应信息

• 作为产物：
  描述：

  3-溴-2-羟基-5-甲基苯甲醛 、 若丹明B酰肼 在 溶剂黄146 作用下， 以 乙醇 为溶剂， 反应 8.0h， 生成 3-bromo-5-methylsalicylaldehyde rhodamine B hydrazone
  参考文献：
  名称：

  A selectively rhodamine-based colorimetric probe for detecting copper(II) ion

  摘要：

  A novel rhodamine derivative 3-bromo-5-methylsalicylaldehyde rhodamine B hydrazone (BMSRH) has been synthesized by reacting rhodamine B hydrazide with 3-bromo-5-methylsalicylaldehyde and developed as a new colorimetric probe for the selective and sensitive detection of Cu2+. Addition of Cu2+ to the solution of BMSRH results in a rapid color change from colorless to red together with an obvious new band appeared at 552 nm in the UV-vis absorption spectra. This change is attributed to the spirocycle form of BMSRH opened via coordination with Cu2+ in a 1:1 stoichiometry and their association constant is determined as 3.2 x 10(4) L mol(-1). Experimental results indicate that the BMSRH can provide a rapid, selective and sensitive response to Cu2+ with a linear dynamic range 0.667-240 mu mol/L. Common interferent ions do not show any interference on the Cu2+ determination. It is anticipated that BMSRH can be a good candidate probe and has potential application for Cu2+ determination. The proposed probe exhibits the following advantages: a quick, simple and facile synthesis. (C) 2014 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.saa.2014.04.006