Einecs 285-971-0 | 85169-28-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油磷脂
• 英文名称: Einecs 285-971-0
• 英文别名: [3-[2-(dimethylamino)ethoxy-hydroxyphosphoryl]oxy-2-hydroxypropyl] hexadecanoate
• CAS: 85169-28-4
• 化学式: C₂₃H₄₈NO₇P
• 分子量: 481.6
• InChiKey: PXQWHFCKRBFTHV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  32
• 可旋转键数：
  24
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.96
• 拓扑面积：
  106
• 氢给体数：
  2
• 氢受体数：
  8

文献信息

• [EN] TEXAPHYRIN-PHOSPHOLIPID CONJUGATES AND METHODS OF PREPARING SAME<br/>[FR] CONJUGUÉS DE TEXAPHYRINE-PHOSPHOLIPIDE ET LEURS PROCÉDÉS DE PRÉPARATION
  申请人：UNIV HEALTH NETWORK

  公开号：WO2016165006A1

  公开（公告）日：2016-10-20

  There is provided herein, a texaphyrin-phospholipid conjugate, wherein the texaphyrin- phospholipid conjugate comprises a texaphyrin, texaphyrin derivative or texaphyrin analog covalently attached to a lipid side chain of a phospholipid.

  本文提供了一种脂质-铁菁共轭物，其中该脂质-铁菁共轭物包括一种铁菁、铁菁衍生物或铁菁类似物，其以共价键连接到磷脂的脂肪侧链上。
• Texaphyrin-phospholipid conjugates and methods of preparing same
  申请人：UNIVERSITY HEALTH NETWORK

  公开号：US10729792B2

  公开（公告）日：2020-08-04

  There is provided herein, a texaphyrin-phospholipid conjugate, wherein the texaphyrin-phospholipid conjugate comprises a texaphyrin, texaphyrin derivative or texaphyrin analog covalently attached to a lipid side chain of a phospholipid.

  本文提供了一种texaphyrin-磷脂共轭物，其中texaphyrin-磷脂共轭物包括共价连接到磷脂脂质侧链上的texaphyrin、texaphyrin衍生物或texaphyrin类似物。
• BIOMARKERS USEFUL FOR DIAGNOSING PROSTATE CANCER, AND METHODS THEREOF
  申请人：Ritchie Shawn

  公开号：US20090127454A1

  公开（公告）日：2009-05-21

  The present invention describes a method for predicting a health-state indicative of the presence of prostate cancer. The method measures the intensities of specific small biochemicals, called metabolites, in a blood sample from a patient with an undetermined health-state, and compares these intensities to the intensities observed in a population of healthy individuals and/or to the intensities previously observed in a population of confirmed prostate cancer-positive individuals. The method enables a practitioner to determine the probability that a screened patient is positive for prostate cancer.
• BIOMARKERS FOR DIAGNOSING MULTIPLE SCLEROSIS, AND METHODS THEREOF
  申请人：Cook Lisa

  公开号：US20100062472A1

  公开（公告）日：2010-03-11

  The present invention describes methods for the diagnosis and differential diagnosis of the different forms of multiple sclerosis The methods measure the intensities of specific small molecules called metabolites in samples from patients with clinically diagnosed relapsmg-remittmg or primary-progressive forms of multiple sclerosis and compare these intensities to the intensities observed in a population of healthy individuals, thus identifying markers of multiple sclerosis A method is also provided for the differential diagnosis of subjects afflicted with relapsing-renitting multiple sclerosis from secondary-progressive multiple sclerosis.
• LIPID ACYLTRANSFERASE PROTEINS AND METHODS OF MAKING THEM
  申请人：Brunstedt Janne

  公开号：US20130034627A1

  公开（公告）日：2013-02-07

  The present invention provides a method for preparing a variant lipid acyltransferase enzyme by expressing a nucleotide sequence encoding a lipid acyltransferase which may comprise at least one modification at a position(s) which corresponds in the encoded amino acid sequence to an amino acid(s) located in a) the canyon region of the enzyme (i.e. preferably amino acid residues 31, 27, 85, 86, 119, and 120); and/or b) insertion site 1 (i.e. amino acid residues 22-36) and/or c) insertion site 2 (i.e. amino acid residues 74-88), wherein the canyon region, insertion site 1 and/or insertion site 2 are defined as that region which when aligned based on primary or tertiary structure corresponds to the canyon region, insertion site 1 or insertion site 2 (or the corresponding amino acid residues taught above) of the enzyme shown herein as SEQ ID No. 16 or 6 in a host organism.