6-Methyl-1-trityloxy-heptan-4-ol | 138613-33-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 三苯基化合物
• 英文名称: 6-Methyl-1-trityloxy-heptan-4-ol
• 英文别名: 6-methyl-1-trityloxyheptan-4-ol
• CAS: 138613-33-9
• 化学式: C₂₇H₃₂O₂
• 分子量: 388.55
• InChiKey: QRSSFTBLMXWYNB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.5
• 重原子数：
  29
• 可旋转键数：
  10
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  6-Methyl-1-trityloxy-heptan-4-ol 在 palladium on activated charcoal 、 氢气 、 三氧化硫吡啶 作用下， 生成 Sulfuric acid mono-[1-(3-hydroxy-propyl)-3-methyl-butyl] ester
  参考文献：
  名称：

  Musclide-A1, -A2, and -B, cardiotonic potentiating principles from musk

  摘要：

  Three new aliphatic sulfates, musclide-A1 (a mixture of 1a and 2a), -A2 (4a), and -B (6a), were isolated from musk, one of the most famous traditional Chinese medicines and their structures were determined. These compounds have a cardiotonic potentiating activity.

  DOI：

  10.1016/s0040-4039(00)74316-4
• 作为产物：
  描述：

  2,3-二氢呋喃 、 ISOBUTYLMAGNESIUM BROMIDE 、 三苯基氯甲烷 在 4-二甲氨基吡啶 、 氢气 、 三乙胺 作用下， 生成 6-Methyl-1-trityloxy-heptan-4-ol
  参考文献：
  名称：

  Musclide-A1, -A2, and -B, cardiotonic potentiating principles from musk

  摘要：

  Three new aliphatic sulfates, musclide-A1 (a mixture of 1a and 2a), -A2 (4a), and -B (6a), were isolated from musk, one of the most famous traditional Chinese medicines and their structures were determined. These compounds have a cardiotonic potentiating activity.

  DOI：

  10.1016/s0040-4039(00)74316-4