5-(hydroxyphenoxymethyl)-2-oxazolidinone | 61874-84-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 5-(hydroxyphenoxymethyl)-2-oxazolidinone
• 英文别名: 5-(4-hydroxyphenoxymethyl)-2-oxazolidinone；5-[(4-Hydroxyphenoxy)methyl]-1,3-oxazolidin-2-one
• CAS: 61874-84-8
• 化学式: C₁₀H₁₁NO₄
• 分子量: 209.202
• InChiKey: PXNAKYCQKFYZID-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  67.8
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  丙烯酰氯 、 5-(hydroxyphenoxymethyl)-2-oxazolidinone 在 三乙胺 作用下， 以 四氢呋喃 为溶剂， 反应 3.0h， 以31.8%的产率得到4-(2-oxo-5-oxazolidinylmethoxy)phenyl acrylate
  参考文献：
  名称：

  Preparation and Complex Formation of Polymers Anchoring 2-Oxazolidinone

  摘要：

  Polymers anchoring 3-unsubstituted 2-oxazolidinone were prepared and their complex formation with phenol and mercury(II) acetate were investigated. Preformed poly(4-hydroxystyrene) was treated with tris(2,3-epoxypropyl) isocyanurate to give a polymer containing 2-oxazolidinone residues within the limits of 57.7 mol%. Polymers carrying 2-oxazolidinone were also prepared through the homopolymerization and copolymerization of 4-(2-oxo-5-oxazolidinylmethoxy)phenyl acrylate. The effective concentration of 2-oxazolidinone residue in the polymers, which is accessible to phenol, was determined on the assumption that the polymer-bound 2-oxazolidinone and phenol formed a 1 : 1 complex. 2-Oxazolidinone and a mercury atom formed a 2 : 1 complex; this relation on the molar ratio applies to all forms of complexes between the mercury atom and the 2-oxazolidinone residue in the polymers.

  DOI：

  10.1246/bcsj.61.3559