N-(2-bromo-3-nitro-[1]naphthyl)-acetamide | 92025-23-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: N-(2-bromo-3-nitro-[1]naphthyl)-acetamide
• 英文别名: 1-Acetamido-2-brom-3-nitronaphthalin；N-(2-bromo-3-nitro-[1]naphthyl)-acetamide；N-(2-Brom-3-nitro-[1]naphthyl)-acetamid；2-Brom-3-nitro-1-acetamino-naphthalin
• CAS: 92025-23-5
• 化学式: C₁₂H₉BrN₂O₃
• 分子量: 309.119
• InChiKey: VRFSSQPLGKYPEF-UHFFFAOYSA-N

物化性质

• 熔点：
  240 °C
• 沸点：
  473.1±35.0 °C(Predicted)
• 密度：
  1.674±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.47
• 重原子数：
  18.0
• 可旋转键数：
  2.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  72.24
• 氢给体数：
  1.0
• 氢受体数：
  3.0

反应信息

• 作为反应物：
  描述：

  N-(2-bromo-3-nitro-[1]naphthyl)-acetamide 在 硫酸 、 溶剂黄146 作用下， 生成 2-溴-3-硝基萘
  参考文献：
  名称：

  Bilateral coexistent calcaneonavicular and talocalcaneal tarsal coalition: A case report

  摘要：

  Tarsal coalition refers to a union of two or more tarsal bones. The union may be fibrous, cartilaginous, or bony. The most common sites of tarsal coalition reported in the literature are the calcaneonavicular, the talocalcaneal, and, less commonly, the talonavicular areas. Bilateral coexistent multiple tarsal coalitions are a rare occurrence. The authors present a case report of a 17-year-old boy with bilateral coexistent calcaneonavicular and talonavicular bars. The diagnosis was established by radiographs and CT scanning. The patient was treated conservatively with immobilization of the foot in a below-knee walking plaster cast followed by the use of an orthosis with a lateral iron and a medial T strap. The patient was pain-free at 2-year follow-up.

  DOI：

  10.1016/s1067-2516(02)80038-2
• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 乙醇 、 水 、 溴 、 potassium bromide 作用下， 生成 N-(2-bromo-3-nitro-[1]naphthyl)-acetamide
  参考文献：
  名称：

  Bilateral coexistent calcaneonavicular and talocalcaneal tarsal coalition: A case report

  摘要：

  Tarsal coalition refers to a union of two or more tarsal bones. The union may be fibrous, cartilaginous, or bony. The most common sites of tarsal coalition reported in the literature are the calcaneonavicular, the talocalcaneal, and, less commonly, the talonavicular areas. Bilateral coexistent multiple tarsal coalitions are a rare occurrence. The authors present a case report of a 17-year-old boy with bilateral coexistent calcaneonavicular and talonavicular bars. The diagnosis was established by radiographs and CT scanning. The patient was treated conservatively with immobilization of the foot in a below-knee walking plaster cast followed by the use of an orthosis with a lateral iron and a medial T strap. The patient was pain-free at 2-year follow-up.

  DOI：

  10.1016/s1067-2516(02)80038-2