5-(Cyanomethyl)-2'-deoxycytidine | 919360-77-3

• 分子结构分类: 有机化合物 - 核苷、核苷酸和类似物 - 嘧啶核苷
• 英文名称: 5-(Cyanomethyl)-2'-deoxycytidine
• 英文别名: 2-[4-amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxopyrimidin-5-yl]acetonitrile
• CAS: 919360-77-3
• 化学式: C₁₁H₁₄N₄O₄
• 分子量: 266.25
• InChiKey: ADTUYFILUJEVOR-DJLDLDEBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.1
• 重原子数：
  19
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.55
• 拓扑面积：
  132
• 氢给体数：
  3
• 氢受体数：
  5

文献信息

• Use of nucleotide analogs in the analysis of oligonucleotide mixtures and in highly multiplexed nucleic acid sequencing
  申请人：The Trustees of Boston University

  公开号：US20020045178A1

  公开（公告）日：2002-04-18

  Methods and kits that use nucleotide analogs to confer increased accuracy and improved resolution in the analysis and sequencing of oligonucleotide mixtures are provided.

  提供了使用核苷酸类似物提高寡核苷酸混合物分析和测序准确性和分辨率的方法和试剂盒。
• Use of nucleotide analogs in the analysis of oligonucleotide mixtures and highly multiplexed nucleic acid sequencing
  申请人：——

  公开号：US20040077004A1

  公开（公告）日：2004-04-22

  Methods kits and systems that use nucleotide analogs to confer increased accuracy and improved resolution in the analysis and sequencing of oligonucleotide mixtures are provided.

  提供了使用核苷酸类似物提高寡核苷酸混合物分析和测序准确性和分辨率的方法、试剂盒和系统。
• USE OF NUCLEOTIDE ANALOGS IN THE ANALYSIS OF OLIGONUCLEOTIDE MIXTURES AND IN HIGHLY MULTIPLEXED NUCLEIC ACID SEQUENCING
  申请人：The Trustees of Boston University

  公开号：EP1373561A2

  公开（公告）日：2004-01-02
• USE OF MASS-MATCHED NUCLEOTIDES IN THE ANALYSIS OF OLIGONUCLEOTIDE MIXTURES AND IN HIGHLY MULTIPLEXED NUCLEIC ACID SEQUENCING
  申请人：THE TRUSTEES OF BOSTON UNIVERSITY

  公开号：EP1373561B1

  公开（公告）日：2009-02-18
• US6660229B2
  申请人：——

  公开号：US6660229B2

  公开（公告）日：2003-12-09