2-Fluoro-4-[(1E)-3-oxo-1-propen-1-yl]benzonitrile | 219873-07-1

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂醛
• 英文名称: 2-Fluoro-4-[(1E)-3-oxo-1-propen-1-yl]benzonitrile
• 英文别名: 2-fluoro-4-[(E)-3-oxoprop-1-enyl]benzonitrile
• CAS: 219873-07-1
• 化学式: C₁₀H₆FNO
• 分子量: 175.162
• InChiKey: CAAVFINYAZQKOP-OWOJBTEDSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  40.9
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• Carboline antiparasitics
  申请人：Zoetis Services LLC

  公开号：US10570129B2

  公开（公告）日：2020-02-25

  The present invention provides Formula (1) compounds that are gamma-carbolines, Formula (1) wherein R1a, R1b, R1c, R1d, R2, R3, and “-” are as defined herein; veterinary acceptable salts thereof, and stereoisomers thereof, which act as parasiticides, in particular, endoparasiticides.

  本发明提供了属于γ-羰基化合物的式(1)化合物，式(1)中的R1a、R1b、R1c、R1d、R2、R3和"-"如本文所定义；其兽药可接受盐及其立体异构体，可作为杀寄生虫剂，特别是内吸性杀寄生虫剂。
• CARBOLINE ANTIPARASITICS
  申请人：ZOETIS SERVICES LLC

  公开号：US20200031822A1

  公开（公告）日：2020-01-30

  The present invention provides Formula (1) compounds that are gamma-carbolines, Formula (1) wherein R1 a, R1 b, R1 c, R1d, R2, R3, and “-” are as defined herein; veterinary acceptable salts thereof, and stereoisomers thereof, which act as parasiticides, in particular, endoperasiticides.