{[2-(9H-Purin-9-yl)ethoxy]methyl}phosphonic acid | 116455-17-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 咪唑并嘧啶类
• 英文名称: {[2-(9H-Purin-9-yl)ethoxy]methyl}phosphonic acid
• 英文别名: 2-purin-9-ylethoxymethylphosphonic acid
• CAS: 116455-17-5
• 化学式: C₈H₁₁N₄O₄P
• 分子量: 258.17
• InChiKey: JBHAAMMGTTXFQQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.9
• 重原子数：
  17
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  110
• 氢给体数：
  2
• 氢受体数：
  7

文献信息

• Antiretroviral bases
  申请人：INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC

  公开号：EP0454427B1

  公开（公告）日：1995-12-06
• Nucleotide analogues for the treatment of viral infections
  申请人：Ustav Organicke Chemie A Biochemie Akademie Ved Ceske Republiky

  公开号：EP0821690B1

  公开（公告）日：2012-06-13
• PHOSPHOANTIGEN SALTS OF ORGANIC BASES AND METHODS FOR THEIR CRYSTALLIZATION
  申请人：Innate Pharma

  公开号：EP1933848A2

  公开（公告）日：2008-06-25
• Phosphoantigen Salts Of Organic Bases And Methods For Their Crystallization
  申请人：Coquerel Gerard

  公开号：US20080300222A1

  公开（公告）日：2008-12-04

  The invention provides novel phosphoantigen salts and novel crystalline phases of phosphoantigens salts, that the latter including non-solvated polymorphs, and solvates useful as pharmaceuticals. The invention also provides pharmaceutical compositions comprising, and processes for making, novel phosphoantigen crystalline phases. Methods of using such compositions for the treatment of disease, immunostimulatory or immune response modifying use are also provided. The invention also provides method for obtaining phosphoantigen crystals as well as highly pure phosphoantigen compositions.
• US5733896A
  申请人：——

  公开号：US5733896A

  公开（公告）日：1998-03-31