[(3R,3aR,6S,6aR)-3-hydroxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-6-yl] 3-methylbutanoate | 84207-87-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 呋喃类
• 英文名称: [(3R,3aR,6S,6aR)-3-hydroxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-6-yl] 3-methylbutanoate
• CAS: 84207-87-4
• 化学式: C₁₁H₁₈O₅
• 分子量: 230.261
• InChiKey: DZPSAJYREGQQBP-JZSSXWJLSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  16
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.91
• 拓扑面积：
  65
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  异戊酸酐 、 异山梨醇 反应 1.0h， 以72%的产率得到[(3R,3aR,6S,6aR)-3-hydroxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-6-yl] 3-methylbutanoate
  参考文献：
  名称：

  Regioselektive Acylierung von 1,4:3,6-Dianhydro-D-glucit

  摘要：

  1,4:3,6-二脱氢-D-葡萄糖醇的区域选择性酰化 1,4:3,6-二脱氢-D-葡萄糖醇在重金属盐存在下与酸酐发生酰化反应，可生成具有高区域选择性的 5-内向酰化物，且检测不到大量异构的 2-酰化物。在有酯化催化剂存在的情况下，加热含有不同量的 1,4:3,6-二脱氢-D-葡萄糖醇、2-和 5-单乙酸酯以及 2,5-二乙酸酯的酰化混合物，同时蒸馏掉沸点较低的 2-乙酸酯，就会发生酰基迁移，优先选择 2-外位。

  DOI：

  10.1055/s-1987-27878

文献信息

• DIANHYDROHEXITOL DIESTER COALESCING AGENT
  申请人：Elementis Specialties, Inc.

  公开号：EP2531565A1

  公开（公告）日：2012-12-12
• [EN] DIANHYDROHEXITOL DIESTER COALESCING AGENT<br/>[FR] AGENT COALESCENT DIESTER DE DIANHYDROHEXITOL
  申请人：ELEMENTIS SPECIALTIES INC

  公开号：WO2011097443A1

  公开（公告）日：2011-08-11

  A film-forming composition including a water-based film-forming polymer having a minimum film forming temperature and a diester(s) of one or more dianhydrohexitols, wherein said dianhydrohexitol diester has a volatile organic content of less than 20 wt.%. Use of such film-forming compositions reduces minimum film forming temperature of the water based film- forming polymer by 10° C to 30° C; and produces a film on a surface wherein said film has properties selected from the group consisting of: 20° gloss value, 60° gloss value, hardness value and combinations thereof, comparable to a film formed from a water based composition containing a standard coalescent aid. The dianhydrohexitol diester includes an isosorbide diester where the ester group has three to 8 carbon atoms. The water based film-forming polymer includes an acrylic resin, a vinyl acrylic resin, a styrene acrylic resin, a vinyl acetate ethylene resin, alkyd resin, ethylene vinyl acrylate resin and combinations thereof.
• Regioselektive Acylierung von 1,4:3,6-Dianhydro-D-glucit
  作者：Peter Stoss、Peter Merrath、Günther Schlüter

  DOI：10.1055/s-1987-27878

  日期：——

  Regioselective Acylation of 1,4:3,6-Dianhydro-D-glucitol Acylation of 1,4:3,6-dianhydro-D-glucitol with anhydrides in the presence of heavy metal salts affords 5-endo-acylates with high regioselectivity, without detectable amounts of the isomeric 2-acylates. Acyl group migration occurs with preference for the 2-exo-position, on heating an acylation mixture, which contains varying amounts of 1,4:3,6-dianhydro-D-glucitol, 2- and 5-monoacylate and 2,5-diacylate, in the presence of reesterification catalysts and whilst distilling off the lower boiling 2-acylate.

  1,4:3,6-二脱氢-D-葡萄糖醇的区域选择性酰化 1,4:3,6-二脱氢-D-葡萄糖醇在重金属盐存在下与酸酐发生酰化反应，可生成具有高区域选择性的 5-内向酰化物，且检测不到大量异构的 2-酰化物。在有酯化催化剂存在的情况下，加热含有不同量的 1,4:3,6-二脱氢-D-葡萄糖醇、2-和 5-单乙酸酯以及 2,5-二乙酸酯的酰化混合物，同时蒸馏掉沸点较低的 2-乙酸酯，就会发生酰基迁移，优先选择 2-外位。