(+/-)-(1,2-bis(diphenylphosphino)ethane)(3-phthalimido-2-oxo-1-oxabutane-1,4-diyl)nickel | 156368-20-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异吲哚及其衍生物
• 英文名称: (+/-)-(1,2-bis(diphenylphosphino)ethane)(3-phthalimido-2-oxo-1-oxabutane-1,4-diyl)nickel
• CAS: 156368-20-6
• 化学式: C₃₇H₃₁NNiO₄P₂
• 分子量: 674.295
• InChiKey: KYSFAZQPQJUVJM-KDKNQRMFSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  (+/-)-(2,9-dimethyl-1,10-phenanthroline)(3-phthalimido-2-oxo-1-oxabutane-1,4-diyl)nickel 、 1,2-双(二苯基膦)乙烷 以 二氯甲烷 为溶剂， 以30%的产率得到(+/-)-(1,2-bis(diphenylphosphino)ethane)(3-phthalimido-2-oxo-1-oxabutane-1,4-diyl)nickel
  参考文献：
  名称：

  Reactivity of a Nickelacycle Derived from Aspartic Acid: Alkylations, Insertions, and Oxidations

  摘要：

  The five-membered nickelacycle derived from aspartic acid by oxidative addition followed by decarbonylation reacts with alkyl iodides and bromides to give a-amino acids, after hydrolysis of the reaction products. Carbonylation products were, however, observed with benzyl or allyl bromide. The involvement of radicals in the alkylation reaction pathway has also been explored. Oxidation of the nickelacycle with N-methylmorpholine N-oxide or dioxygen gave N-protected serine. On the other hand, benzoyl peroxide promoted the insertion of carbon monoxide or isocyanides into the Ni-C bond. Phenylacetylene and 1-octyne also insert into the Ni-C bond of the nickelacycle to give alkenyl or alkynyl products.

  DOI：

  10.1021/om00018a020